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Murcko scaffold

Ring system with 4 rings and 20 atoms

6 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
20
Chemicals
6
With full pages
3
Scaffold SMILES

O=C1Nc2ccccc2C1=Cc1cc2c([nH]1)CCCC2

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C1Nc2ccccc2C1=Cc1cc2c([nH]1)CCCC2

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 6 of 6 chemicals

2,3-Dihydro-N,N-dimethyl-2-oxo-3-((4,5,6,7-tetrahydro-1H-indol-2-yl)methylene)-1H-indole-5-sulfonamide chemical structure, C19H21N3O3S, CAS 330161-87-0
2,3-Dihydro-N,N-dimethyl-2-oxo-3-((4,5,6,7-tetrahydro-1H-indol-2-yl)methylene)-1H-indole-5-sulfonamide
CAS 330161-87-0C19H21N3O3S
5-Bromo-1,3-dihydro-3-[(4,5,6,7-tetrahydro-1H-indol-2-yl)methylene]-2H-indol-2-one chemical structure, C17H15BrN2O, CAS 204003-89-4
5-Bromo-1,3-dihydro-3-[(4,5,6,7-tetrahydro-1H-indol-2-yl)methylene]-2H-indol-2-one
CAS 204003-89-4C17H15BrN2O
Su6656 chemical structure, C19H21N3O3S, CAS 1240328-42-0
Su6656
CAS 1240328-42-0C19H21N3O3S
3-((4,5,6,7-Tetrahydro-1H-indol-2-yl)methylene)indolin-2-one chemical structure, C17H16N2O, CAS 204003-85-0
3-((4,5,6,7-Tetrahydro-1H-indol-2-yl)methylene)indolin-2-one
CAS 204003-85-0C17H16N2O
Vegfr 2 kinase inhibitor II chemical structure, C17H15BrN2O, CAS 288144-20-7
Vegfr 2 kinase inhibitor II
CAS 288144-20-7C17H15BrN2O
Indolin-2-one deriv. 4c chemical structure, C17H17N3O3S, CAS 288144-21-8
Indolin-2-one deriv. 4c
CAS 288144-21-8C17H17N3O3S