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Murcko scaffold

1,3,4,6,7,11b-Hexahydro-2H-benzo(a)quinolizin-2-one scaffold

43 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
15
Chemicals
43
With full pages
5
Scaffold SMILES

O=C1CCN2CCc3ccccc3C2C1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 1,3,4,6,7,11b-Hexahydro-2H-benzo(a)quinolizin-2-one page
Murcko scaffold O=C1CCN2CCc3ccccc3C2C1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 43 of 43 chemicals

Tetrabenazine chemical structure, C19H27NO3, CAS 58-46-8
Tetrabenazine
CAS 58-46-8C19H27NO3
Sct 1 chemical structure, C18H22N2O3, CAS 23158-25-0
Sct 1
CAS 23158-25-0C18H22N2O3
3-Ethyl-1,3,4,6,7,11b-hexahydro-9,10-dimethoxy-2H-benzo[a]quinolizin-2-one chemical structure, C17H23NO3, CAS 846-66-2
3-Ethyl-1,3,4,6,7,11b-hexahydro-9,10-dimethoxy-2H-benzo[a]quinolizin-2-one
CAS 846-66-2C17H23NO3
9,10-Dimethoxy-1,3,4,6,7,11b-hexahydro-2H-pyrido[2,1-a]isoquinolin-2-one chemical structure, C15H19NO3, CAS 841-95-2
9,10-Dimethoxy-1,3,4,6,7,11b-hexahydro-2H-pyrido[2,1-a]isoquinolin-2-one
CAS 841-95-2C15H19NO3
3-Butyl-9,10-dimethoxy-1,3,4,6,7,11b-hexahydrobenzo[a]quinolizin-2-one chemical structure, C19H27NO3, CAS 19328-35-9
3-Butyl-9,10-dimethoxy-1,3,4,6,7,11b-hexahydrobenzo[a]quinolizin-2-one
CAS 19328-35-9C19H27NO3
9,10-Dimethoxy-3-(2-methylprop-2-enyl)-1,3,4,6,7,11b-hexahydrobenzo[a]quinolizin-2-one chemical structure, C19H25NO3, CAS 67455-70-3
9,10-Dimethoxy-3-(2-methylprop-2-enyl)-1,3,4,6,7,11b-hexahydrobenzo[a]quinolizin-2-one
CAS 67455-70-3C19H25NO3
3-But-3-enyl-9,10-dimethoxy-1,3,4,6,7,11b-hexahydrobenzo[a]quinolizin-2-one chemical structure, C19H25NO3, CAS 67455-69-0
3-But-3-enyl-9,10-dimethoxy-1,3,4,6,7,11b-hexahydrobenzo[a]quinolizin-2-one
CAS 67455-69-0C19H25NO3
(3R,11bR)-1,3,4,6,7,11b-Hexahydro-9,10-dimethoxy-3-(2-methylpropyl)-2H-benzo(a)quinolizin-2-one chemical structure, C19H27NO3, CAS 1026016-83-0
(3R,11bR)-1,3,4,6,7,11b-Hexahydro-9,10-dimethoxy-3-(2-methylpropyl)-2H-benzo(a)quinolizin-2-one
CAS 1026016-83-0C19H27NO3
2H-Benzo(a)quinolizine-3-propanenitrile, 1,3,4,6,7,11b-hexahydro-9,10-diethoxy-2-oxo- chemical structure, C20H26N2O3, CAS 59894-95-0
2H-Benzo(a)quinolizine-3-propanenitrile, 1,3,4,6,7,11b-hexahydro-9,10-diethoxy-2-oxo-
CAS 59894-95-0C20H26N2O3
Tetrabenazine impurity 31 chemical structure, C19H27NO3
Tetrabenazine impurity 31
C19H27NO3
(3S,11bR)-3-Isobutyl-9,10-dimethoxy-3,4,6,7-tetrahydro-1H-pyrido[2,1-a]isoquinolin-2(11bH)-one chemical structure, C19H27NO3, CAS 1381929-92-5
(3S,11bR)-3-Isobutyl-9,10-dimethoxy-3,4,6,7-tetrahydro-1H-pyrido[2,1-a]isoquinolin-2(11bH)-one
CAS 1381929-92-5C19H27NO3
1,3,4,6,7,11b-Hexahydro-2H-benzo(a)quinolizin-2-one chemical structure, C13H15NO, CAS 715-52-6
1,3,4,6,7,11b-Hexahydro-2H-benzo(a)quinolizin-2-one
CAS 715-52-6C13H15NO
(-)-Tetrabenazine chemical structure, C19H27NO3, CAS 1026016-84-1
(-)-Tetrabenazine
CAS 1026016-84-1C19H27NO3
cis-(1)-3-Ethyl-1,3,4,6,7,11b-hexahydro-9,10-dimethoxybenzo(a)quinolizin-2-one chemical structure, C17H23NO3, CAS 51300-04-0
cis-(1)-3-Ethyl-1,3,4,6,7,11b-hexahydro-9,10-dimethoxybenzo(a)quinolizin-2-one
CAS 51300-04-0C17H23NO3
Agn-PC-0nif0E chemical structure, C17H24ClNO3, CAS 20821-23-2
Agn-PC-0nif0E
CAS 20821-23-2C17H24ClNO3
3-Ethyl-9,10-dimethoxy-5-methyl-1,3,4,6,7,11b-hexahydrobenzo[a]quinolizin-5-ium-2-one, iodide chemical structure, C18H26INO3, CAS 67455-66-7
3-Ethyl-9,10-dimethoxy-5-methyl-1,3,4,6,7,11b-hexahydrobenzo[a]quinolizin-5-ium-2-one, iodide
CAS 67455-66-7C18H26INO3
2H-Benzo[a]quinolizin-2-one, 3-butyl-1,3,4,6,7,11b-hexahydro-9,10-dimethoxy-, hydrochloride chemical structure, C19H28ClNO3, CAS 67455-68-9
2H-Benzo[a]quinolizin-2-one, 3-butyl-1,3,4,6,7,11b-hexahydro-9,10-dimethoxy-, hydrochloride
CAS 67455-68-9C19H28ClNO3
2H-Benzo[a]quinolizin-2-one,1,3,4,6,7,11b-hexahydro-9,10-dimethoxy-3-propyl-, hydrochloride (1:1) chemical structure, C18H26ClNO3, CAS 67455-67-8
2H-Benzo[a]quinolizin-2-one,1,3,4,6,7,11b-hexahydro-9,10-dimethoxy-3-propyl-, hydrochloride (1:1)
CAS 67455-67-8C18H26ClNO3
10-Hydroxy-9-methoxy-3-(2-methylpropyl)-1,3,4,6,7,11b-hexahydrobenzo[a]quinolizin-2-one chemical structure, C18H25NO3, CAS 1214267-46-5
10-Hydroxy-9-methoxy-3-(2-methylpropyl)-1,3,4,6,7,11b-hexahydrobenzo[a]quinolizin-2-one
CAS 1214267-46-5C18H25NO3
Lpr52Q8myq chemical structure, C18H25NO3, CAS 1214267-47-6
Lpr52Q8myq
CAS 1214267-47-6C18H25NO3
MK2Prn3tls chemical structure, C18H25NO3, CAS 1146952-98-8
MK2Prn3tls
CAS 1146952-98-8C18H25NO3
9,10-Dihydroxy-3-isobutyl-3,4,6,7-tetrahydro-1H-pyrido[2,1-a]isoquinolin-2(11bH)-one chemical structure, C17H23NO3, CAS 89929-27-1
9,10-Dihydroxy-3-isobutyl-3,4,6,7-tetrahydro-1H-pyrido[2,1-a]isoquinolin-2(11bH)-one
CAS 89929-27-1C17H23NO3
DTR-I chemical structure, C17H23NO3, CAS 2220998-55-8
DTR-I
CAS 2220998-55-8C17H23NO3
9-Hydroxy-3-isobutyl-10-methoxy-1,3,4,6,7,11b-hexahydro-2H-pyrido[2,1-a]isoquinolin-2-one chemical structure, C18H25NO3, CAS 149183-89-1
9-Hydroxy-3-isobutyl-10-methoxy-1,3,4,6,7,11b-hexahydro-2H-pyrido[2,1-a]isoquinolin-2-one
CAS 149183-89-1C18H25NO3