Murcko scaffold
1,3-Dihydroimidazo(4,5-b)pyridin-2-one scaffold
132 chemicals on CompoundList share this ring system.
- Rings
- 2
- Scaffold atoms
- 10
- Chemicals
- 132
- With full pages
- 22
Scaffold SMILES
O=c1[nH]c2cccnc2[nH]1
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
![Murcko scaffold O=c1[nH]c2cccnc2[nH]1](/scaffold/PGDIPOWQYRAOSK-UHFFFAOYSA-N/structure.svg)
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 48 of 132 chemicals
1,3-Dihydroimidazo(4,5-b)pyridin-2-one
CAS 16328-62-4C6H5N3O
![6-Iodo-3-methyl-1H-imidazo[4,5-b]pyridin-2(3H)-one chemical structure, C7H6IN3O, CAS 309742-29-8](/s/FWRVUOOGWBABBW-UHFFFAOYSA-N.svg)
6-Iodo-3-methyl-1H-imidazo[4,5-b]pyridin-2(3H)-one
CAS 309742-29-8C7H6IN3O
![Imidazo[4,5-b]pyridin-2-one, 2,3-dihydro-5,6-dibromo-3-methyl- chemical structure, C7H5Br2N3O, CAS 361365-07-3](/s/NMFZVVCHHIEFGJ-UHFFFAOYSA-N.svg)
Imidazo[4,5-b]pyridin-2-one, 2,3-dihydro-5,6-dibromo-3-methyl-
CAS 361365-07-3C7H5Br2N3O
![6-Chloro-3-methyl-1H-imidazo[4,5-b]pyridin-2(3H)-one chemical structure, C7H6ClN3O, CAS 370074-74-1](/s/UBIAVKDDKVKPDS-UHFFFAOYSA-N.svg)
6-Chloro-3-methyl-1H-imidazo[4,5-b]pyridin-2(3H)-one
CAS 370074-74-1C7H6ClN3O
![6-Bromo-1,3-dimethyl-1H-imidazo[4,5-b]pyridin-2(3H)-one chemical structure, C8H8BrN3O, CAS 234771-64-3](/s/AZVVIPSHNZHTHP-UHFFFAOYSA-N.svg)
6-Bromo-1,3-dimethyl-1H-imidazo[4,5-b]pyridin-2(3H)-one
CAS 234771-64-3C8H8BrN3O
![6-Chloro-1,3-dimethyl-1,3-dihydro-2H-imidazo[4,5-b]pyridin-2-one chemical structure, C8H8ClN3O, CAS 300695-86-7](/s/TYEATTAFFFVPHE-UHFFFAOYSA-N.svg)
6-Chloro-1,3-dimethyl-1,3-dihydro-2H-imidazo[4,5-b]pyridin-2-one
CAS 300695-86-7C8H8ClN3O
![6-Chloro-1H-imidazo[4,5-b]pyridin-2(3H)-one chemical structure, C6H4ClN3O, CAS 304861-88-9](/s/IYVCQOHFGFWGEG-UHFFFAOYSA-N.svg)
6-Chloro-1H-imidazo[4,5-b]pyridin-2(3H)-one
CAS 304861-88-9C6H4ClN3O
![2H-Imidazo[4,5-b]pyridin-2-one, 1,3-dihydro-1,3-dimethyl- chemical structure, C8H9N3O, CAS 21991-37-7](/s/PRTMVBNVWJXLBN-UHFFFAOYSA-N.svg)
2H-Imidazo[4,5-b]pyridin-2-one, 1,3-dihydro-1,3-dimethyl-
CAS 21991-37-7C8H9N3O
![1-Methyl-1H-imidazo[4,5-b]pyridin-2(3H)-one chemical structure, C7H7N3O, CAS 50339-06-5](/s/JWBRNYGXJYMMSI-UHFFFAOYSA-N.svg)
1-Methyl-1H-imidazo[4,5-b]pyridin-2(3H)-one
CAS 50339-06-5C7H7N3O
![4-Methyl-1H-imidazo[4,5-b]pyridin-2-one chemical structure, C7H7N3O, CAS 50339-08-7](/s/FGDQAKJUQZYHPV-UHFFFAOYSA-N.svg)
4-Methyl-1H-imidazo[4,5-b]pyridin-2-one
CAS 50339-08-7C7H7N3O
![3-Methyl-1H-imidazo[4,5-b]pyridin-2(3H)-one chemical structure, C7H7N3O, CAS 21991-39-9](/s/UNTZTFGDFVDERP-UHFFFAOYSA-N.svg)
3-Methyl-1H-imidazo[4,5-b]pyridin-2(3H)-one
CAS 21991-39-9C7H7N3O
![6-Bromo-3H-imidazo[4,5-b]pyridin-2-ol chemical structure, C6H4BrN3O, CAS 148038-83-9](/s/VHCRLTJPUNUZRN-UHFFFAOYSA-N.svg)
6-Bromo-3H-imidazo[4,5-b]pyridin-2-ol
CAS 148038-83-9C6H4BrN3O
![(7-Chloro-2-oxo-2,3-dihydro-1H-imidazo[4,5-b]pyridin-5-yl)-carbamic acid ethyl ester chemical structure, C9H9ClN4O3, CAS 68375-41-7](/s/YCQUGGFNTSZSPT-UHFFFAOYSA-N.svg)
(7-Chloro-2-oxo-2,3-dihydro-1H-imidazo[4,5-b]pyridin-5-yl)-carbamic acid ethyl ester
CAS 68375-41-7C9H9ClN4O3
![5,6-Dichloro-1H,2H,3H-imidazo[4,5-b]pyridin-2-one chemical structure, C6H3Cl2N3O, CAS 361365-08-4](/s/ITKBBOLEUZVKAE-UHFFFAOYSA-N.svg)
5,6-Dichloro-1H,2H,3H-imidazo[4,5-b]pyridin-2-one
CAS 361365-08-4C6H3Cl2N3O
6-Bromo-5-methyl-1H-imidazo(4,5-B)pyridin-2-ol
CAS 116035-73-5C7H6BrN3O
![5-Amino-1,3-dihydro-2H-imidazo[4,5-b]pyridin-2-one chemical structure, C6H6N4O, CAS 40851-87-4](/s/GXAJPMIFZGNMQY-UHFFFAOYSA-N.svg)
5-Amino-1,3-dihydro-2H-imidazo[4,5-b]pyridin-2-one
CAS 40851-87-4C6H6N4O
![1,3-Dihydro-5-nitro-2H-imidazo[4,5-B]pyridin-2-one chemical structure, C6H4N4O3, CAS 22902-67-6](/s/TXAMXRHQYUGXOV-UHFFFAOYSA-N.svg)
1,3-Dihydro-5-nitro-2H-imidazo[4,5-B]pyridin-2-one
CAS 22902-67-6C6H4N4O3
![2-Hydroxy-1,5,6-trimethylimidazo [4,5-B] pyridine chemical structure, C9H11N3O, CAS 887406-59-9](/s/RNIWKAXDCMVXKQ-UHFFFAOYSA-N.svg)
2-Hydroxy-1,5,6-trimethylimidazo [4,5-B] pyridine
CAS 887406-59-9C9H11N3O
![3-Ethyl-1H-imidazo[4,5-b]pyridin-2-one chemical structure, C8H9N3O, CAS 32282-16-9](/s/HHHWGPUYRPSEGQ-UHFFFAOYSA-N.svg)
3-Ethyl-1H-imidazo[4,5-b]pyridin-2-one
CAS 32282-16-9C8H9N3O
![tert-Butyl 2-oxo-1H-imidazo[4,5-b]pyridine-3(2H)-carboxylate chemical structure, C11H13N3O3, CAS 1027159-01-8](/s/OYIYQMHHTPPHAT-UHFFFAOYSA-N.svg)
tert-Butyl 2-oxo-1H-imidazo[4,5-b]pyridine-3(2H)-carboxylate
CAS 1027159-01-8C11H13N3O3
![6-Bromo-3-methyl-1H-imidazo[4,5-b]pyridin-2(3H)-one chemical structure, C7H6BrN3O, CAS 166047-16-1](/s/BEIHAUJWQREPNF-UHFFFAOYSA-N.svg)
6-Bromo-3-methyl-1H-imidazo[4,5-b]pyridin-2(3H)-one
CAS 166047-16-1C7H6BrN3O
![5,7-Dimethyl-1H-imidazo[4,5-b]pyridin-2(3H)-one chemical structure, C8H9N3O, CAS 116636-30-7](/s/ZTCGJUGNDSJQFV-UHFFFAOYSA-N.svg)
5,7-Dimethyl-1H-imidazo[4,5-b]pyridin-2(3H)-one
CAS 116636-30-7C8H9N3O
![5-(Trifluoromethyl)-1,3-dihydro-2H-imidazo[4,5-B]pyridin-2-one chemical structure, C7H4F3N3O, CAS 683242-80-0](/s/KYVCWKKIEJZBAY-UHFFFAOYSA-N.svg)
5-(Trifluoromethyl)-1,3-dihydro-2H-imidazo[4,5-B]pyridin-2-one
CAS 683242-80-0C7H4F3N3O
![6-Trifluoromethyl-1,3-dihydro-imidazo[4,5-b]pyridin-2-one chemical structure, C7H4F3N3O, CAS 438190-87-5](/s/WJRWBBDJRQDIHQ-UHFFFAOYSA-N.svg)
6-Trifluoromethyl-1,3-dihydro-imidazo[4,5-b]pyridin-2-one
CAS 438190-87-5C7H4F3N3O
- 5-Methyl-1,3-dihydro-2H-imidazo[4,5-b]pyridin-2-one77712-95-9C7H7N3O
- 1H-Imidazo[4,5-b]pyridine-1-carboxylic acid, 2,3-dihydro-2-oxo-, ethyl ester103409-28-5C9H9N3O3
- tert-Butyl 2-oxo-1H,2H,3H-imidazo[4,5-B]pyridine-1-carboxylate103409-33-2C11H13N3O3
- 1,3-Di-tert-butyl 2-oxo-1H,2H,3H-imidazo[4,5-B]pyridine-1,3-dicarboxylate103409-34-3C16H21N3O5
- tert-Butyl 1-methyl-2-oxo-1,2-dihydro-3H-imidazo[4,5-b]pyridine-3-carboxylate103432-67-3C12H15N3O3
- 1,5-Dimethyl-1,3-dihydro-imidazo[4,5-b]pyridin-2-one155789-86-9C8H9N3O
- 1,3-Dihydro-1,6-dimethyl-2H-imidazo[4,5-b]pyridin-2-one155789-87-0C8H9N3O
- 3,5-Dimethyl-1,3-dihydro-imidazo[4,5-b]pyridin-2-one155789-89-2C8H9N3O
- 3,6-Dimethyl-1,3-dihydro-imidazo[4,5-b]pyridin-2-one155789-90-5C8H9N3O
- 3,7-Dimethyl-1,3-dihydro-imidazo[4,5-b]pyridin-2-one155789-91-6C8H9N3O
- 5,6,7-Trimethyl-1,3-dihydroimidazo[4,5-b]pyridin-2-one116599-53-2C9H11N3O
- 5-Chloro-1-methyl-1H-imidazo[4,5-b]pyridin-2(3H)-one40852-06-0C7H6ClN3O
- 1 suppliers5-Chloro-1H,2H,3H-imidazo(4,5-b)pyridin-2-one40851-98-7C6H4ClN3O
- 7-Methyl-1H,2H,3H-imidazo[4,5-b]pyridin-2-one518038-75-0C7H7N3O
- 3-Isopropyl-1,3-dihydro-2H-imidazo[4,5-b]pyridin-2-one20934-71-8C9H11N3O
- 1-(Propan-2-yl)-1H,2H,3H-imidazo[4,5-b]pyridin-2-one20934-70-7C9H11N3O
- 7-Amino-1H-imidazo[4,5-b]pyridin-2(3H)-one371933-31-2C6H6N4O
- 1 suppliers6-Chloro-1-ethyl-1,3-dihydro-2H-imidazo[4,5-b]pyridin-2-one1064782-28-0C8H8ClN3O
- 1-Ethyl-1H-imidazo[4,5-b]pyridin-2(3H)-one448211-19-6C8H9N3O
- 3-({2-Oxo-1H,2H,3H-imidazo[4,5-b]pyridin-5-yl}carbamoyl)propanoic acid1110717-63-9C10H10N4O4
- 3-({1,3-Dimethyl-2-oxo-1H,2H,3H-imidazo[4,5-b]pyridin-5-yl}carbamoyl)propanoic acid1110717-64-0C12H14N4O4
- 3-({1,3-Diethyl-2-oxo-1H,2H,3H-imidazo[4,5-b]pyridin-5-yl}carbamoyl)propanoic acid1110717-65-1C14H18N4O4
- Ethyl 2-{6-bromo-2-oxo-1H,2H,3H-imidazo[4,5-b]pyridin-3-yl}acetate1204599-81-4C10H10BrN3O3
- 1 suppliers7-Chloro-1H,2H,3H-imidazo(4,5-b)pyridin-2-one1202780-76-4C6H4ClN3O
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