CompoundList
Sign in
Murcko scaffold

Ring system with 4 rings and 27 atoms

42 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
27
Chemicals
42
With full pages
4
Scaffold SMILES

O=C(CSc1nnc(-c2ccco2)n1Cc1ccco1)Nc1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(CSc1nnc(-c2ccco2)n1Cc1ccco1)Nc1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 42 of 42 chemicals

2-[5-(2-Furyl)-4-(2-furylmethyl)(1,2,4-triazol-3-ylthio)]-N-(2-methoxy-5-methy lphenyl)acetamide chemical structure, C21H20N4O4S, CAS 573971-63-8
2-[5-(2-Furyl)-4-(2-furylmethyl)(1,2,4-triazol-3-ylthio)]-N-(2-methoxy-5-methy lphenyl)acetamide
CAS 573971-63-8C21H20N4O4S
2-[[5-(2-Furanyl)-4-(2-furanylmethyl)-1,2,4-triazol-3-yl]thio]-N-(2-methoxyphenyl)acetamide chemical structure, C20H18N4O4S, CAS 577981-68-1
2-[[5-(2-Furanyl)-4-(2-furanylmethyl)-1,2,4-triazol-3-yl]thio]-N-(2-methoxyphenyl)acetamide
CAS 577981-68-1C20H18N4O4S
N-(2-Ethoxyphenyl)-2-{[5-(furan-2-yl)-4-(furan-2-ylmethyl)-4H-1,2,4-triazol-3-yl]sulfanyl}acetamide chemical structure, C21H20N4O4S, CAS 585555-62-0
N-(2-Ethoxyphenyl)-2-{[5-(furan-2-yl)-4-(furan-2-ylmethyl)-4H-1,2,4-triazol-3-yl]sulfanyl}acetamide
CAS 585555-62-0C21H20N4O4S
2-{[5-(Furan-2-yl)-4-(furan-2-ylmethyl)-4H-1,2,4-triazol-3-yl]sulfanyl}-N-(3-methylphenyl)acetamide chemical structure, C20H18N4O3S, CAS 557069-42-8
2-{[5-(Furan-2-yl)-4-(furan-2-ylmethyl)-4H-1,2,4-triazol-3-yl]sulfanyl}-N-(3-methylphenyl)acetamide
CAS 557069-42-8C20H18N4O3S
N-(3-Fluorophenyl)-2-((5-(furan-2-yl)-4-(furan-2-ylmethyl)-4H-1,2,4-triazol-3-yl)thio)acetamide chemical structure, C19H15FN4O3S, CAS 557067-86-4
N-(3-Fluorophenyl)-2-((5-(furan-2-yl)-4-(furan-2-ylmethyl)-4H-1,2,4-triazol-3-yl)thio)acetamide
CAS 557067-86-4C19H15FN4O3S
N-(2-Fluorophenyl)-2-{[5-(furan-2-yl)-4-(furan-2-ylmethyl)-4H-1,2,4-triazol-3-yl]sulfanyl}acetamide chemical structure, C19H15FN4O3S, CAS 557067-90-0
N-(2-Fluorophenyl)-2-{[5-(furan-2-yl)-4-(furan-2-ylmethyl)-4H-1,2,4-triazol-3-yl]sulfanyl}acetamide
CAS 557067-90-0C19H15FN4O3S
2-{[5-(Furan-2-yl)-4-(furan-2-ylmethyl)-4H-1,2,4-triazol-3-yl]sulfanyl}-N-(4-methylphenyl)acetamide chemical structure, C20H18N4O3S, CAS 557069-30-4
2-{[5-(Furan-2-yl)-4-(furan-2-ylmethyl)-4H-1,2,4-triazol-3-yl]sulfanyl}-N-(4-methylphenyl)acetamide
CAS 557069-30-4C20H18N4O3S
N-(4-Fluorophenyl)-2-[[5-(furan-2-yl)-4-(furan-2-ylmethyl)-1,2,4-triazol-3-yl]sulfanyl]acetamide chemical structure, C19H15FN4O3S, CAS 573936-93-3
N-(4-Fluorophenyl)-2-[[5-(furan-2-yl)-4-(furan-2-ylmethyl)-1,2,4-triazol-3-yl]sulfanyl]acetamide
CAS 573936-93-3C19H15FN4O3S
N-(2,6-Dimethylphenyl)-2-{[5-(furan-2-yl)-4-(furan-2-ylmethyl)-4H-1,2,4-triazol-3-yl]sulfanyl}acetamide chemical structure, C21H20N4O3S, CAS 769133-28-0
N-(2,6-Dimethylphenyl)-2-{[5-(furan-2-yl)-4-(furan-2-ylmethyl)-4H-1,2,4-triazol-3-yl]sulfanyl}acetamide
CAS 769133-28-0C21H20N4O3S
N-[2-Chloro-5-(trifluoromethyl)phenyl]-2-{[5-(furan-2-yl)-4-(furan-2-ylmethyl)-4H-1,2,4-triazol-3-yl]sulfanyl}acetamide chemical structure, C20H14ClF3N4O3S, CAS 573934-12-0
N-[2-Chloro-5-(trifluoromethyl)phenyl]-2-{[5-(furan-2-yl)-4-(furan-2-ylmethyl)-4H-1,2,4-triazol-3-yl]sulfanyl}acetamide
CAS 573934-12-0C20H14ClF3N4O3S
2-{[5-(Furan-2-yl)-4-(furan-2-ylmethyl)-4H-1,2,4-triazol-3-yl]sulfanyl}-N-(2,4,6-trimethylphenyl)acetamide chemical structure, C22H22N4O3S, CAS 573946-76-6
2-{[5-(Furan-2-yl)-4-(furan-2-ylmethyl)-4H-1,2,4-triazol-3-yl]sulfanyl}-N-(2,4,6-trimethylphenyl)acetamide
CAS 573946-76-6C22H22N4O3S
N-(3-Chlorophenyl)-2-{[5-(furan-2-yl)-4-(furan-2-ylmethyl)-4H-1,2,4-triazol-3-yl]sulfanyl}acetamide chemical structure, C19H15ClN4O3S, CAS 840480-16-2
N-(3-Chlorophenyl)-2-{[5-(furan-2-yl)-4-(furan-2-ylmethyl)-4H-1,2,4-triazol-3-yl]sulfanyl}acetamide
CAS 840480-16-2C19H15ClN4O3S
N-(2,4-Difluorophenyl)-2-{[5-(furan-2-yl)-4-(furan-2-ylmethyl)-4H-1,2,4-triazol-3-yl]sulfanyl}acetamide chemical structure, C19H14F2N4O3S, CAS 677731-09-8
N-(2,4-Difluorophenyl)-2-{[5-(furan-2-yl)-4-(furan-2-ylmethyl)-4H-1,2,4-triazol-3-yl]sulfanyl}acetamide
CAS 677731-09-8C19H14F2N4O3S
N-(3-Bromophenyl)-2-{[5-(furan-2-yl)-4-(furan-2-ylmethyl)-4H-1,2,4-triazol-3-yl]sulfanyl}acetamide chemical structure, C19H15BrN4O3S, CAS 577980-77-9
N-(3-Bromophenyl)-2-{[5-(furan-2-yl)-4-(furan-2-ylmethyl)-4H-1,2,4-triazol-3-yl]sulfanyl}acetamide
CAS 577980-77-9C19H15BrN4O3S
2-{[5-(Furan-2-yl)-4-(furan-2-ylmethyl)-4H-1,2,4-triazol-3-yl]sulfanyl}-N-[4-(propan-2-yl)phenyl]acetamide chemical structure, C22H22N4O3S, CAS 760951-00-6
2-{[5-(Furan-2-yl)-4-(furan-2-ylmethyl)-4H-1,2,4-triazol-3-yl]sulfanyl}-N-[4-(propan-2-yl)phenyl]acetamide
CAS 760951-00-6C22H22N4O3S
N-(3,5-Dimethylphenyl)-2-{[5-(furan-2-yl)-4-(furan-2-ylmethyl)-4H-1,2,4-triazol-3-yl]sulfanyl}acetamide chemical structure, C21H20N4O3S, CAS 577990-72-8
N-(3,5-Dimethylphenyl)-2-{[5-(furan-2-yl)-4-(furan-2-ylmethyl)-4H-1,2,4-triazol-3-yl]sulfanyl}acetamide
CAS 577990-72-8C21H20N4O3S
N-(3,4-Dimethoxyphenyl)-2-{[5-(furan-2-yl)-4-(furan-2-ylmethyl)-4H-1,2,4-triazol-3-yl]sulfanyl}acetamide chemical structure, C21H20N4O5S, CAS 577996-36-2
N-(3,4-Dimethoxyphenyl)-2-{[5-(furan-2-yl)-4-(furan-2-ylmethyl)-4H-1,2,4-triazol-3-yl]sulfanyl}acetamide
CAS 577996-36-2C21H20N4O5S
N-(2-Bromophenyl)-2-{[5-(furan-2-yl)-4-(furan-2-ylmethyl)-4H-1,2,4-triazol-3-yl]sulfanyl}acetamide chemical structure, C19H15BrN4O3S, CAS 573696-62-5
N-(2-Bromophenyl)-2-{[5-(furan-2-yl)-4-(furan-2-ylmethyl)-4H-1,2,4-triazol-3-yl]sulfanyl}acetamide
CAS 573696-62-5C19H15BrN4O3S
N-(4-Chloro-2-methoxy-5-methylphenyl)-2-{[5-(furan-2-yl)-4-(furan-2-ylmethyl)-4H-1,2,4-triazol-3-yl]sulfanyl}acetamide chemical structure, C21H19ClN4O4S, CAS 769134-44-3
N-(4-Chloro-2-methoxy-5-methylphenyl)-2-{[5-(furan-2-yl)-4-(furan-2-ylmethyl)-4H-1,2,4-triazol-3-yl]sulfanyl}acetamide
CAS 769134-44-3C21H19ClN4O4S
N-(3-Fluoro-4-methylphenyl)-2-{[5-(furan-2-yl)-4-(furan-2-ylmethyl)-4H-1,2,4-triazol-3-yl]sulfanyl}acetamide chemical structure, C20H17FN4O3S, CAS 578762-58-0
N-(3-Fluoro-4-methylphenyl)-2-{[5-(furan-2-yl)-4-(furan-2-ylmethyl)-4H-1,2,4-triazol-3-yl]sulfanyl}acetamide
CAS 578762-58-0C20H17FN4O3S
N-(4-Acetylamino-phenyl)-2-(5-furan-2-yl-4-furan-2-ylmethyl-4H-[1,2,4]triazol-3-ylsulfanyl)-acetamide chemical structure, C21H19N5O4S, CAS 577695-93-3
N-(4-Acetylamino-phenyl)-2-(5-furan-2-yl-4-furan-2-ylmethyl-4H-[1,2,4]triazol-3-ylsulfanyl)-acetamide
CAS 577695-93-3C21H19N5O4S
N-(4-Bromophenyl)-2-{[5-(furan-2-yl)-4-(furan-2-ylmethyl)-4H-1,2,4-triazol-3-yl]sulfanyl}acetamide chemical structure, C19H15BrN4O3S, CAS 577960-66-8
N-(4-Bromophenyl)-2-{[5-(furan-2-yl)-4-(furan-2-ylmethyl)-4H-1,2,4-triazol-3-yl]sulfanyl}acetamide
CAS 577960-66-8C19H15BrN4O3S
N-[4-(Dimethylamino)phenyl]-2-{[5-(furan-2-yl)-4-(furan-2-ylmethyl)-4H-1,2,4-triazol-3-yl]sulfanyl}acetamide chemical structure, C21H21N5O3S, CAS 578698-24-5
N-[4-(Dimethylamino)phenyl]-2-{[5-(furan-2-yl)-4-(furan-2-ylmethyl)-4H-1,2,4-triazol-3-yl]sulfanyl}acetamide
CAS 578698-24-5C21H21N5O3S
N-[5-(Acetylamino)-2-methoxyphenyl]-2-[5-(2-furyl)-4-(2-furylmethyl)(1,2,4-tri azol-3-ylthio)]acetamide chemical structure, C22H21N5O5S, CAS 578700-38-6
N-[5-(Acetylamino)-2-methoxyphenyl]-2-[5-(2-furyl)-4-(2-furylmethyl)(1,2,4-tri azol-3-ylthio)]acetamide
CAS 578700-38-6C22H21N5O5S