CompoundList
Sign in
Murcko scaffold

Ring system with 4 rings and 25 atoms

16 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
25
Chemicals
16
With full pages
3
Scaffold SMILES

O=C(COc1ccc2ccc(=O)oc2c1)c1ccc2ccccc2c1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(COc1ccc2ccc(=O)oc2c1)c1ccc2ccccc2c1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 16 of 16 chemicals

4-Methyl-7-(2-naphthalen-2-yl-2-oxoethoxy)chromen-2-one chemical structure, C22H16O4, CAS 374908-82-4
4-Methyl-7-(2-naphthalen-2-yl-2-oxoethoxy)chromen-2-one
CAS 374908-82-4C22H16O4
4-Ethyl-8-methyl-7-(2-naphthalen-2-yl-2-oxoethoxy)chromen-2-one chemical structure, C24H20O4, CAS 375358-82-0
4-Ethyl-8-methyl-7-(2-naphthalen-2-yl-2-oxoethoxy)chromen-2-one
CAS 375358-82-0C24H20O4
4,8-Dimethyl-7-[2-(2-naphthyl)-2-oxoethoxy]-2H-chromen-2-one chemical structure, C23H18O4, CAS 670245-06-4
4,8-Dimethyl-7-[2-(2-naphthyl)-2-oxoethoxy]-2H-chromen-2-one
CAS 670245-06-4C23H18O4
Ethyl 3-{4,8-dimethyl-7-[2-(2-naphthyl)-2-oxoethoxy]-2-oxo-2H-chromen-3-yl}propanoate chemical structure, C28H26O6, CAS 670242-78-1
Ethyl 3-{4,8-dimethyl-7-[2-(2-naphthyl)-2-oxoethoxy]-2-oxo-2H-chromen-3-yl}propanoate
CAS 670242-78-1C28H26O6
4-Ethyl-7-[2-(2-naphthyl)-2-oxoethoxy]-2H-chromen-2-one chemical structure, C23H18O4, CAS 433306-18-4
4-Ethyl-7-[2-(2-naphthyl)-2-oxoethoxy]-2H-chromen-2-one
CAS 433306-18-4C23H18O4
8-Methyl-7-[2-(2-naphthyl)-2-oxoethoxy]-4-propyl-2H-chromen-2-one chemical structure, C25H22O4, CAS 670245-07-5
8-Methyl-7-[2-(2-naphthyl)-2-oxoethoxy]-4-propyl-2H-chromen-2-one
CAS 670245-07-5C25H22O4
3,4,8-Trimethyl-7-[2-(2-naphthyl)-2-oxoethoxy]-2H-chromen-2-one chemical structure, C24H20O4, CAS 433317-99-8
3,4,8-Trimethyl-7-[2-(2-naphthyl)-2-oxoethoxy]-2H-chromen-2-one
CAS 433317-99-8C24H20O4
3-Ethyl-4-methyl-7-[2-(2-naphthyl)-2-oxoethoxy]-2H-chromen-2-one chemical structure, C24H20O4, CAS 670244-60-7
3-Ethyl-4-methyl-7-[2-(2-naphthyl)-2-oxoethoxy]-2H-chromen-2-one
CAS 670244-60-7C24H20O4
Ethyl 3-{4-methyl-7-[2-(2-naphthyl)-2-oxoethoxy]-2-oxo-2H-chromen-3-yl}propanoate chemical structure, C27H24O6, CAS 670242-04-3
Ethyl 3-{4-methyl-7-[2-(2-naphthyl)-2-oxoethoxy]-2-oxo-2H-chromen-3-yl}propanoate
CAS 670242-04-3C27H24O6
Methyl {6-chloro-4-methyl-7-[2-(naphthalen-2-yl)-2-oxoethoxy]-2-oxo-2H-chromen-3-yl}acetate chemical structure, C25H19ClO6, CAS 670244-24-3
Methyl {6-chloro-4-methyl-7-[2-(naphthalen-2-yl)-2-oxoethoxy]-2-oxo-2H-chromen-3-yl}acetate
CAS 670244-24-3C25H19ClO6
4-Butyl-7-(2-naphthalen-2-yl-2-oxoethoxy)chromen-2-one chemical structure, C25H22O4, CAS 376371-29-8
4-Butyl-7-(2-naphthalen-2-yl-2-oxoethoxy)chromen-2-one
CAS 376371-29-8C25H22O4
3-Ethyl-4,8-dimethyl-7-[2-(2-naphthyl)-2-oxoethoxy]-2H-chromen-2-one chemical structure, C25H22O4, CAS 670244-59-4
3-Ethyl-4,8-dimethyl-7-[2-(2-naphthyl)-2-oxoethoxy]-2H-chromen-2-one
CAS 670244-59-4C25H22O4
7-(2-Naphthalen-2-yl-2-oxoethoxy)-4-propylchromen-2-one chemical structure, C24H20O4, CAS 375362-66-6
7-(2-Naphthalen-2-yl-2-oxoethoxy)-4-propylchromen-2-one
CAS 375362-66-6C24H20O4
Methyl {4-methyl-7-[2-(naphthalen-2-yl)-2-oxoethoxy]-2-oxo-2H-chromen-3-yl}acetate chemical structure, C25H20O6, CAS 670244-62-9
Methyl {4-methyl-7-[2-(naphthalen-2-yl)-2-oxoethoxy]-2-oxo-2H-chromen-3-yl}acetate
CAS 670244-62-9C25H20O6
Methyl {4,8-dimethyl-7-[2-(naphthalen-2-yl)-2-oxoethoxy]-2-oxo-2H-chromen-3-yl}acetate chemical structure, C26H22O6, CAS 670244-61-8
Methyl {4,8-dimethyl-7-[2-(naphthalen-2-yl)-2-oxoethoxy]-2-oxo-2H-chromen-3-yl}acetate
CAS 670244-61-8C26H22O6
3-Hexyl-4,8-dimethyl-7-[2-(2-naphthyl)-2-oxoethoxy]-2H-chromen-2-one chemical structure, C29H30O4, CAS 670244-56-1
3-Hexyl-4,8-dimethyl-7-[2-(2-naphthyl)-2-oxoethoxy]-2H-chromen-2-one
CAS 670244-56-1C29H30O4