CompoundList
Sign in
Murcko scaffold

Ring system with 5 rings and 32 atoms

6 chemicals on CompoundList share this ring system.

Rings
5
Scaffold atoms
32
Chemicals
6
With full pages
2
Scaffold SMILES

O=C(N=c1nc2cc(OCCCN3CCOCC3)ccc2c2n1CCN2)c1cncnc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(N=c1nc2cc(OCCCN3CCOCC3)ccc2c2n1CCN2)c1cncnc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 6 of 6 chemicals

Copanlisib chemical structure, C23H28N8O4, CAS 1032568-63-0
Copanlisib
CAS 1032568-63-0C23H28N8O4
Copanlisib dihydrochloride chemical structure, C23H30Cl2N8O4, CAS 1402152-13-9
Copanlisib dihydrochloride
CAS 1402152-13-9C23H30Cl2N8O4
Copanlisib hydrochloride hydrate chemical structure, C23H38Cl2N8O8, CAS 1402152-46-8
Copanlisib hydrochloride hydrate
CAS 1402152-46-8C23H38Cl2N8O8
2-Amino-N-{7-methoxy-8-[3-(morpholin-4-yl)propoxy]-2,3-dihydroimidazo[1,2-c]quinazolin-5-yl}-4-methylpyrimidine-5-carboxamide chemical structure, C24H30N8O4, CAS 1032569-02-0
2-Amino-N-{7-methoxy-8-[3-(morpholin-4-yl)propoxy]-2,3-dihydroimidazo[1,2-c]quinazolin-5-yl}-4-methylpyrimidine-5-carboxamide
CAS 1032569-02-0C24H30N8O4
N-[7-Methoxy-8-(3-morpholin-4-ylpropoxy)-2,3-dihydroimidazo[1,2-c]quinazolin-5-yl]pyrimidine-5-carboxamide chemical structure, C23H27N7O4, CAS 1032568-37-8
N-[7-Methoxy-8-(3-morpholin-4-ylpropoxy)-2,3-dihydroimidazo[1,2-c]quinazolin-5-yl]pyrimidine-5-carboxamide
CAS 1032568-37-8C23H27N7O4
Copanlisib-d8 chemical structure, C23H28N8O4, CAS 2168537-35-5
Copanlisib-d8
CAS 2168537-35-5C23H28N8O4