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Murcko scaffold

Ring system with 2 rings and 15 atoms

12 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
15
Chemicals
12
With full pages
3
Scaffold SMILES

O=C1NC(=S)SC1=CC=Cc1ccco1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C1NC(=S)SC1=CC=Cc1ccco1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 12 of 12 chemicals

2-Thioxo-5-[(1Z,2E)-3-(2-furanyl)-2-propenylidene]thiazolidine-4-one chemical structure, C10H7NO2S2, CAS 37530-63-5
2-Thioxo-5-[(1Z,2E)-3-(2-furanyl)-2-propenylidene]thiazolidine-4-one
CAS 37530-63-5C10H7NO2S2
(5Z)-5-[(2E)-3-(Furan-2-yl)prop-2-en-1-ylidene]-3-methyl-2-thioxo-1,3-thiazolidin-4-one chemical structure, C11H9NO2S2, CAS 37530-67-9
(5Z)-5-[(2E)-3-(Furan-2-yl)prop-2-en-1-ylidene]-3-methyl-2-thioxo-1,3-thiazolidin-4-one
CAS 37530-67-9C11H9NO2S2
2-[5-((2E)-3-(2-Furyl)prop-2-enylidene)-4-oxo-2-thioxo-1,3-thiazolidin-3-yl]ac etic acid chemical structure, C12H9NO4S2, CAS 848996-29-2
2-[5-((2E)-3-(2-Furyl)prop-2-enylidene)-4-oxo-2-thioxo-1,3-thiazolidin-3-yl]ac etic acid
CAS 848996-29-2C12H9NO4S2
4-[(5Z)-5-[(E)-3-(Furan-2-yl)prop-2-enylidene]-4-oxo-2-sulfanylidene-1,3-thiazolidin-3-yl]butanoic acid chemical structure, C14H13NO4S2, CAS 853904-11-7
4-[(5Z)-5-[(E)-3-(Furan-2-yl)prop-2-enylidene]-4-oxo-2-sulfanylidene-1,3-thiazolidin-3-yl]butanoic acid
CAS 853904-11-7C14H13NO4S2
(5Z)-5-[(E)-3-(Furan-2-yl)-2-methylprop-2-enylidene]-2-sulfanylidene-1,3-thiazolidin-4-one chemical structure, C11H9NO2S2, CAS 37530-64-6
(5Z)-5-[(E)-3-(Furan-2-yl)-2-methylprop-2-enylidene]-2-sulfanylidene-1,3-thiazolidin-4-one
CAS 37530-64-6C11H9NO2S2
5-[3-(5-Nitro-2-furanyl)-2-propen-1-ylidene]-2-thioxo-4-thiazolidinone chemical structure, C10H6N2O4S2, CAS 27464-57-9
5-[3-(5-Nitro-2-furanyl)-2-propen-1-ylidene]-2-thioxo-4-thiazolidinone
CAS 27464-57-9C10H6N2O4S2
6-[5-((2E)-3-(2-Furyl)prop-2-enylidene)-4-oxo-2-thioxo-1,3-thiazolidin-3-yl]he xanoic acid chemical structure, C16H17NO4S2, CAS 853904-12-8
6-[5-((2E)-3-(2-Furyl)prop-2-enylidene)-4-oxo-2-thioxo-1,3-thiazolidin-3-yl]he xanoic acid
CAS 853904-12-8C16H17NO4S2
3-[5-((2E)-3-(2-Furyl)prop-2-enylidene)-4-oxo-2-thioxo-1,3-thiazolidin-3-yl]pr opanoic acid chemical structure, C13H11NO4S2, CAS 861110-15-8
3-[5-((2E)-3-(2-Furyl)prop-2-enylidene)-4-oxo-2-thioxo-1,3-thiazolidin-3-yl]pr opanoic acid
CAS 861110-15-8C13H11NO4S2
2-((Z)-5-((E)-3-(Furan-2-yl)allylidene)-4-oxo-2-thioxothiazolidin-3-yl)pentanoic acid chemical structure, C15H15NO4S2, CAS 872696-34-9
2-((Z)-5-((E)-3-(Furan-2-yl)allylidene)-4-oxo-2-thioxothiazolidin-3-yl)pentanoic acid
CAS 872696-34-9C15H15NO4S2
2-((Z)-5-((E)-3-(Furan-2-yl)allylidene)-4-oxo-2-thioxothiazolidin-3-yl)propanoic acid chemical structure, C13H11NO4S2, CAS 1164116-77-1
2-((Z)-5-((E)-3-(Furan-2-yl)allylidene)-4-oxo-2-thioxothiazolidin-3-yl)propanoic acid
CAS 1164116-77-1C13H11NO4S2
2-((Z)-5-((E)-3-(Furan-2-yl)allylidene)-4-oxo-2-thioxothiazolidin-3-yl)butanoic acid chemical structure, C14H13NO4S2, CAS 861138-33-2
2-((Z)-5-((E)-3-(Furan-2-yl)allylidene)-4-oxo-2-thioxothiazolidin-3-yl)butanoic acid
CAS 861138-33-2C14H13NO4S2
2-[(5Z)-5-[(E)-3-(Furan-2-yl)prop-2-enylidene]-4-oxo-2-sulfanylidene-1,3-thiazolidin-3-yl]-3-methylbutanoic acid chemical structure, C15H15NO4S2, CAS 1164110-94-4
2-[(5Z)-5-[(E)-3-(Furan-2-yl)prop-2-enylidene]-4-oxo-2-sulfanylidene-1,3-thiazolidin-3-yl]-3-methylbutanoic acid
CAS 1164110-94-4C15H15NO4S2