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Murcko scaffold

Ring system with 2 rings and 16 atoms

10 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
16
Chemicals
10
With full pages
5
Scaffold SMILES

N=C1NC(=O)C(CC(=O)Nc2cccs2)S1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold N=C1NC(=O)C(CC(=O)Nc2cccs2)S1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 10 of 10 chemicals

(E)-Methyl 4,5-dimethyl-2-(2-(3-methyl-2-(methylimino)-4-oxothiazolidin-5-yl)acetamido)thiophene-3-carboxylate chemical structure, C15H19N3O4S2, CAS 1164457-76-4
(E)-Methyl 4,5-dimethyl-2-(2-(3-methyl-2-(methylimino)-4-oxothiazolidin-5-yl)acetamido)thiophene-3-carboxylate
CAS 1164457-76-4C15H19N3O4S2
(Z)-Methyl 5-ethyl-2-(2-(3-methyl-2-(methylimino)-4-oxothiazolidin-5-yl)acetamido)thiophene-3-carboxylate chemical structure, C15H19N3O4S2, CAS 691377-79-4
(Z)-Methyl 5-ethyl-2-(2-(3-methyl-2-(methylimino)-4-oxothiazolidin-5-yl)acetamido)thiophene-3-carboxylate
CAS 691377-79-4C15H19N3O4S2
Methyl 2-({[(2Z)-3-ethyl-2-(ethylimino)-4-oxo-1,3-thiazolidin-5-yl]acetyl}amino)-4,5-dimethylthiophene-3-carboxylate chemical structure, C17H23N3O4S2, CAS 6148-39-6
Methyl 2-({[(2Z)-3-ethyl-2-(ethylimino)-4-oxo-1,3-thiazolidin-5-yl]acetyl}amino)-4,5-dimethylthiophene-3-carboxylate
CAS 6148-39-6C17H23N3O4S2
(Z)-Ethyl 2-(2-(3-ethyl-2-(ethylimino)-4-oxothiazolidin-5-yl)acetamido)-4,5-dimethylthiophene-3-carboxylate chemical structure, C18H25N3O4S2, CAS 329224-71-7
(Z)-Ethyl 2-(2-(3-ethyl-2-(ethylimino)-4-oxothiazolidin-5-yl)acetamido)-4,5-dimethylthiophene-3-carboxylate
CAS 329224-71-7C18H25N3O4S2
(E)-Ethyl 5-ethyl-2-(2-(3-ethyl-2-(ethylimino)-4-oxothiazolidin-5-yl)acetamido)thiophene-3-carboxylate chemical structure, C18H25N3O4S2, CAS 691377-80-7
(E)-Ethyl 5-ethyl-2-(2-(3-ethyl-2-(ethylimino)-4-oxothiazolidin-5-yl)acetamido)thiophene-3-carboxylate
CAS 691377-80-7C18H25N3O4S2
Ethyl 4,5-dimethyl-2-[[2-(3-methyl-2-methylimino-4-oxo-1,3-thiazolidin-5-yl)acetyl]amino]thiophene-3-carboxylate chemical structure, C16H21N3O4S2, CAS 1164457-52-6
Ethyl 4,5-dimethyl-2-[[2-(3-methyl-2-methylimino-4-oxo-1,3-thiazolidin-5-yl)acetyl]amino]thiophene-3-carboxylate
CAS 1164457-52-6C16H21N3O4S2
(E)-Methyl 2-(2-(3-ethyl-2-(ethylimino)-4-oxothiazolidin-5-yl)acetamido)thiophene-3-carboxylate chemical structure, C15H19N3O4S2, CAS 881484-73-7
(E)-Methyl 2-(2-(3-ethyl-2-(ethylimino)-4-oxothiazolidin-5-yl)acetamido)thiophene-3-carboxylate
CAS 881484-73-7C15H19N3O4S2
(E)-Methyl 2-(2-(3-methyl-2-(methylimino)-4-oxothiazolidin-5-yl)acetamido)thiophene-3-carboxylate chemical structure, C13H15N3O4S2, CAS 883279-73-0
(E)-Methyl 2-(2-(3-methyl-2-(methylimino)-4-oxothiazolidin-5-yl)acetamido)thiophene-3-carboxylate
CAS 883279-73-0C13H15N3O4S2
(E)-Methyl 4-ethyl-5-methyl-2-(2-(3-methyl-2-(methylimino)-4-oxothiazolidin-5-yl)acetamido)thiophene-3-carboxylate chemical structure, C16H21N3O4S2, CAS 937698-74-3
(E)-Methyl 4-ethyl-5-methyl-2-(2-(3-methyl-2-(methylimino)-4-oxothiazolidin-5-yl)acetamido)thiophene-3-carboxylate
CAS 937698-74-3C16H21N3O4S2
Methyl 2-[2-(2-imino-4-oxo-1,3-thiazolidin-5-yl)acetamido]-4,5-dimethylthiophene-3-carboxylate chemical structure, C13H15N3O4S2, CAS 405924-84-7
Methyl 2-[2-(2-imino-4-oxo-1,3-thiazolidin-5-yl)acetamido]-4,5-dimethylthiophene-3-carboxylate
CAS 405924-84-7C13H15N3O4S2