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Murcko scaffold

Phenyl 2-pyridylmethyl sulfone scaffold

14 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
16
Chemicals
14
With full pages
4
Scaffold SMILES

O=S(=O)(Cc1ccccn1)c1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the Phenyl 2-pyridylmethyl sulfone page
Murcko scaffold O=S(=O)(Cc1ccccn1)c1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 14 of 14 chemicals

3-Chloro-2-[(phenylsulfonyl)methyl]-5-(trifluoromethyl)pyridine chemical structure, C13H9ClF3NO2S, CAS 338420-49-8
3-Chloro-2-[(phenylsulfonyl)methyl]-5-(trifluoromethyl)pyridine
CAS 338420-49-8C13H9ClF3NO2S
Phenyl 2-pyridylmethyl sulfone chemical structure, C12H11NO2S, CAS 1620-50-4
Phenyl 2-pyridylmethyl sulfone
CAS 1620-50-4C12H11NO2S
Methyl 4-(benzenesulfonyl)-4-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]butanoate chemical structure, C17H15ClF3NO4S, CAS 338406-82-9
Methyl 4-(benzenesulfonyl)-4-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]butanoate
CAS 338406-82-9C17H15ClF3NO4S
4-(Benzenesulfonyl)-4-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]butanamide chemical structure, C16H14ClF3N2O3S, CAS 338406-95-4
4-(Benzenesulfonyl)-4-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]butanamide
CAS 338406-95-4C16H14ClF3N2O3S
4-(Benzenesulfonyl)-4-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]butanoic acid chemical structure, C16H13ClF3NO4S, CAS 338407-19-5
4-(Benzenesulfonyl)-4-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]butanoic acid
CAS 338407-19-5C16H13ClF3NO4S
4-Methylphenyl 2-pyridinylmethyl sulfone chemical structure, C13H13NO2S, CAS 58414-96-3
4-Methylphenyl 2-pyridinylmethyl sulfone
CAS 58414-96-3C13H13NO2S
4-[3-Chloro-5-(trifluoromethyl)-2-pyridinyl]-4-(phenylsulfonyl)butanenitrile chemical structure, C16H12ClF3N2O2S, CAS 338406-76-1
4-[3-Chloro-5-(trifluoromethyl)-2-pyridinyl]-4-(phenylsulfonyl)butanenitrile
CAS 338406-76-1C16H12ClF3N2O2S
4-(Benzenesulfonyl)-4-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]-N-(dimethylaminomethylidene)butanamide chemical structure, C19H19ClF3N3O3S, CAS 338420-80-7
4-(Benzenesulfonyl)-4-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]-N-(dimethylaminomethylidene)butanamide
CAS 338420-80-7C19H19ClF3N3O3S
Ethyl 4-[2-(benzenesulfonylmethyl)pyridin-1-ium-1-yl]but-2-enoate chemical structure, C18H20NO4S+, CAS 6669-64-3
Ethyl 4-[2-(benzenesulfonylmethyl)pyridin-1-ium-1-yl]but-2-enoate
CAS 6669-64-3C18H20NO4S+
2-[3-Chloro-5-(trifluoromethyl)-2-pyridinyl]-2-(phenylsulfonyl)acetaldehyde O-methyloxime chemical structure, C15H12ClF3N2O3S, CAS 338758-57-9
2-[3-Chloro-5-(trifluoromethyl)-2-pyridinyl]-2-(phenylsulfonyl)acetaldehyde O-methyloxime
CAS 338758-57-9C15H12ClF3N2O3S
2-(4-Chlorobenzenesulfonylmethyl)pyridine chemical structure, C12H10ClNO2S, CAS 558465-88-6
2-(4-Chlorobenzenesulfonylmethyl)pyridine
CAS 558465-88-6C12H10ClNO2S
2-[(Benzenesulfonyl)methyl]-1-methylpyridin-1-ium iodide chemical structure, C13H14INO2S, CAS 1804-16-6
2-[(Benzenesulfonyl)methyl]-1-methylpyridin-1-ium iodide
CAS 1804-16-6C13H14INO2S
6-Bromo-3-nitro-2-(toluene-4-sulfonylmethyl)-pyridine chemical structure, C13H11BrN2O4S, CAS 1427587-94-7
6-Bromo-3-nitro-2-(toluene-4-sulfonylmethyl)-pyridine
CAS 1427587-94-7C13H11BrN2O4S
2-[(Benzenesulfonyl)methyl]-4-(trifluoromethyl)pyridine chemical structure, C13H10F3NO2S, CAS 2062071-11-6
2-[(Benzenesulfonyl)methyl]-4-(trifluoromethyl)pyridine
CAS 2062071-11-6C13H10F3NO2S