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Murcko scaffold

Ring system with 4 rings and 28 atoms

13 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
28
Chemicals
13
With full pages
1
Scaffold SMILES

O=C(Cc1coc2ccccc12)Nc1ccc(S(=O)(=O)N2CCCCC2)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(Cc1coc2ccccc12)Nc1ccc(S(=O)(=O)N2CCCCC2)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 13 of 13 chemicals

2-(6-Methyl-1-benzofuran-3-yl)-N-[4-(piperidin-1-ylsulfonyl)phenyl]acetamide chemical structure, C22H24N2O4S, CAS 848619-39-6
2-(6-Methyl-1-benzofuran-3-yl)-N-[4-(piperidin-1-ylsulfonyl)phenyl]acetamide
CAS 848619-39-6C22H24N2O4S
2-(6,7-Dimethyl-1-benzofuran-3-yl)-N-[4-(piperidin-1-ylsulfonyl)phenyl]acetamide chemical structure, C23H26N2O4S, CAS 880397-17-1
2-(6,7-Dimethyl-1-benzofuran-3-yl)-N-[4-(piperidin-1-ylsulfonyl)phenyl]acetamide
CAS 880397-17-1C23H26N2O4S
2-(6,7-Dimethyl-1-benzofuran-3-yl)-N-{4-[(2-methylpiperidin-1-yl)sulfonyl]phenyl}acetamide chemical structure, C24H28N2O4S, CAS 866247-29-2
2-(6,7-Dimethyl-1-benzofuran-3-yl)-N-{4-[(2-methylpiperidin-1-yl)sulfonyl]phenyl}acetamide
CAS 866247-29-2C24H28N2O4S
2-(5-Methyl-1-benzofuran-3-yl)-N-{4-[(4-methylpiperidin-1-yl)sulfonyl]phenyl}acetamide chemical structure, C23H26N2O4S, CAS 880793-12-4
2-(5-Methyl-1-benzofuran-3-yl)-N-{4-[(4-methylpiperidin-1-yl)sulfonyl]phenyl}acetamide
CAS 880793-12-4C23H26N2O4S
2-(6-Methyl-1-benzofuran-3-yl)-N-{4-[(4-methylpiperidin-1-yl)sulfonyl]phenyl}acetamide chemical structure, C23H26N2O4S, CAS 880392-24-5
2-(6-Methyl-1-benzofuran-3-yl)-N-{4-[(4-methylpiperidin-1-yl)sulfonyl]phenyl}acetamide
CAS 880392-24-5C23H26N2O4S
2-(5-Methyl-1-benzofuran-3-yl)-N-{4-[(3-methylpiperidin-1-yl)sulfonyl]phenyl}acetamide chemical structure, C23H26N2O4S, CAS 880404-27-3
2-(5-Methyl-1-benzofuran-3-yl)-N-{4-[(3-methylpiperidin-1-yl)sulfonyl]phenyl}acetamide
CAS 880404-27-3C23H26N2O4S
2-(6-Methyl-1-benzofuran-3-yl)-N-{4-[(3-methylpiperidin-1-yl)sulfonyl]phenyl}acetamide chemical structure, C23H26N2O4S, CAS 880392-16-5
2-(6-Methyl-1-benzofuran-3-yl)-N-{4-[(3-methylpiperidin-1-yl)sulfonyl]phenyl}acetamide
CAS 880392-16-5C23H26N2O4S
2-(4,6-Dimethyl-1-benzofuran-3-yl)-N-[4-(piperidin-1-ylsulfonyl)phenyl]acetamide chemical structure, C23H26N2O4S, CAS 880787-50-8
2-(4,6-Dimethyl-1-benzofuran-3-yl)-N-[4-(piperidin-1-ylsulfonyl)phenyl]acetamide
CAS 880787-50-8C23H26N2O4S
2-(4,6-Dimethyl-1-benzofuran-3-yl)-N-{4-[(3-methylpiperidin-1-yl)sulfonyl]phenyl}acetamide chemical structure, C24H28N2O4S, CAS 880787-38-2
2-(4,6-Dimethyl-1-benzofuran-3-yl)-N-{4-[(3-methylpiperidin-1-yl)sulfonyl]phenyl}acetamide
CAS 880787-38-2C24H28N2O4S
2-(5-Methyl-1-benzofuran-3-yl)-N-[4-(piperidin-1-ylsulfonyl)phenyl]acetamide chemical structure, C22H24N2O4S, CAS 879940-82-6
2-(5-Methyl-1-benzofuran-3-yl)-N-[4-(piperidin-1-ylsulfonyl)phenyl]acetamide
CAS 879940-82-6C22H24N2O4S
2-(6,7-Dimethyl-1-benzofuran-3-yl)-N-{4-[(3-methylpiperidin-1-yl)sulfonyl]phenyl}acetamide chemical structure, C24H28N2O4S, CAS 880396-88-3
2-(6,7-Dimethyl-1-benzofuran-3-yl)-N-{4-[(3-methylpiperidin-1-yl)sulfonyl]phenyl}acetamide
CAS 880396-88-3C24H28N2O4S
2-(6,7-Dimethyl-1-benzofuran-3-yl)-N-{4-[(4-methylpiperidin-1-yl)sulfonyl]phenyl}acetamide chemical structure, C24H28N2O4S, CAS 880397-25-1
2-(6,7-Dimethyl-1-benzofuran-3-yl)-N-{4-[(4-methylpiperidin-1-yl)sulfonyl]phenyl}acetamide
CAS 880397-25-1C24H28N2O4S
N-{4-[(3-Methylpiperidin-1-yl)sulfonyl]phenyl}-2-[5-(propan-2-yl)-1-benzofuran-3-yl]acetamide chemical structure, C25H30N2O4S, CAS 883289-76-7
N-{4-[(3-Methylpiperidin-1-yl)sulfonyl]phenyl}-2-[5-(propan-2-yl)-1-benzofuran-3-yl]acetamide
CAS 883289-76-7C25H30N2O4S