Murcko scaffold
10-Phenyl-1,2,3,4-tetrahydro-5H-benzo[c]furo[3,2-g]chromen-5-one scaffold
18 chemicals on CompoundList share this ring system.
- Rings
- 5
- Scaffold atoms
- 24
- Chemicals
- 18
- With full pages
- 4
Scaffold SMILES
O=c1oc2cc3occ(-c4ccccc4)c3cc2c2c1CCCC2
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 18 of 18 chemicals
![9-Methyl-10-phenyl-1,2,3,4-tetrahydro-5H-benzo[c]furo[3,2-g]chromen-5-one chemical structure, C22H18O3, CAS 374708-39-1](/s/UDOKCFBPGJSCEN-UHFFFAOYSA-N.svg)
9-Methyl-10-phenyl-1,2,3,4-tetrahydro-5H-benzo[c]furo[3,2-g]chromen-5-one
CAS 374708-39-1C22H18O3
![10-(4-Fluorophenyl)-1,2,3,4-tetrahydro-5H-benzo[c]furo[3,2-g]chromen-5-one chemical structure, C21H15FO3, CAS 374757-45-6](/s/CNDBAHOVONZEBJ-UHFFFAOYSA-N.svg)
10-(4-Fluorophenyl)-1,2,3,4-tetrahydro-5H-benzo[c]furo[3,2-g]chromen-5-one
CAS 374757-45-6C21H15FO3
![10-(4-Fluorophenyl)-7-methyl-1,2,3,4-tetrahydro-5H-benzo[c]furo[3,2-g]chromen-5-one chemical structure, C22H17FO3, CAS 374710-33-5](/s/XYFQMYZPNLLBOB-UHFFFAOYSA-N.svg)
10-(4-Fluorophenyl)-7-methyl-1,2,3,4-tetrahydro-5H-benzo[c]furo[3,2-g]chromen-5-one
CAS 374710-33-5C22H17FO3
![10-(4-Methoxyphenyl)-1,2,3,4-tetrahydro-5H-benzo[c]furo[3,2-g]chromen-5-one chemical structure, C22H18O4, CAS 374757-17-2](/s/DQOUUXGTYRFGFO-UHFFFAOYSA-N.svg)
10-(4-Methoxyphenyl)-1,2,3,4-tetrahydro-5H-benzo[c]furo[3,2-g]chromen-5-one
CAS 374757-17-2C22H18O4
![7-Methyl-10-(4-methylphenyl)-1,2,3,4-tetrahydro-5H-benzo[c]furo[3,2-g]chromen-5-one chemical structure, C23H20O3, CAS 370584-49-9](/s/OPQRHKHFEPXXNO-UHFFFAOYSA-N.svg)
7-Methyl-10-(4-methylphenyl)-1,2,3,4-tetrahydro-5H-benzo[c]furo[3,2-g]chromen-5-one
CAS 370584-49-9C23H20O3
![10-(4-Methylphenyl)-1,2,3,4-tetrahydro-5H-benzo[c]furo[3,2-g]chromen-5-one chemical structure, C22H18O3, CAS 370582-90-4](/s/ACGHPJAITBCJDL-UHFFFAOYSA-N.svg)
10-(4-Methylphenyl)-1,2,3,4-tetrahydro-5H-benzo[c]furo[3,2-g]chromen-5-one
CAS 370582-90-4C22H18O3
![10-(3-Methoxyphenyl)-1,2,3,4-tetrahydro-5H-benzo[c]furo[3,2-g]chromen-5-one chemical structure, C22H18O4, CAS 444996-48-9](/s/MVWBWROEAXLDJT-UHFFFAOYSA-N.svg)
10-(3-Methoxyphenyl)-1,2,3,4-tetrahydro-5H-benzo[c]furo[3,2-g]chromen-5-one
CAS 444996-48-9C22H18O4
![7-Methyl-10-phenyl-1,2,3,4-tetrahydro-5H-benzo[c]furo[3,2-g]chromen-5-one chemical structure, C22H18O3, CAS 86557-23-5](/s/NMUIPEPEIZBBPU-UHFFFAOYSA-N.svg)
7-Methyl-10-phenyl-1,2,3,4-tetrahydro-5H-benzo[c]furo[3,2-g]chromen-5-one
CAS 86557-23-5C22H18O3
![10-Phenyl-1,2,3,4-tetrahydro-5H-benzo[c]furo[3,2-g]chromen-5-one chemical structure, C21H16O3, CAS 374702-62-2](/s/PQMCOYZAEROLIX-UHFFFAOYSA-N.svg)
10-Phenyl-1,2,3,4-tetrahydro-5H-benzo[c]furo[3,2-g]chromen-5-one
CAS 374702-62-2C21H16O3
![10-(4-Chlorophenyl)-1,2,3,4-tetrahydro-5H-benzo[c]furo[3,2-g]chromen-5-one chemical structure, C21H15ClO3, CAS 374760-08-4](/s/BRZXSHZSBASSIT-UHFFFAOYSA-N.svg)
10-(4-Chlorophenyl)-1,2,3,4-tetrahydro-5H-benzo[c]furo[3,2-g]chromen-5-one
CAS 374760-08-4C21H15ClO3
![10-(3-Fluoro-4-methoxyphenyl)-1,2,3,4-tetrahydro-5H-benzo[c]furo[3,2-g]chromen-5-one chemical structure, C22H17FO4, CAS 374099-85-1](/s/GIAOYFZSDFUCCH-UHFFFAOYSA-N.svg)
10-(3-Fluoro-4-methoxyphenyl)-1,2,3,4-tetrahydro-5H-benzo[c]furo[3,2-g]chromen-5-one
CAS 374099-85-1C22H17FO4
![10-(3-Methoxyphenyl)-7-methyl-1,2,3,4-tetrahydro-5H-benzo[c]furo[3,2-g]chromen-5-one chemical structure, C23H20O4, CAS 433700-22-2](/s/PFRCPEOHSHJXSX-UHFFFAOYSA-N.svg)
10-(3-Methoxyphenyl)-7-methyl-1,2,3,4-tetrahydro-5H-benzo[c]furo[3,2-g]chromen-5-one
CAS 433700-22-2C23H20O4
![10-(4-Methoxyphenyl)-7-methyl-1,2,3,4-tetrahydro-5H-benzo[c]furo[3,2-g]chromen-5-one chemical structure, C23H20O4, CAS 370585-26-5](/s/VXHOWJMSVNAOSA-UHFFFAOYSA-N.svg)
10-(4-Methoxyphenyl)-7-methyl-1,2,3,4-tetrahydro-5H-benzo[c]furo[3,2-g]chromen-5-one
CAS 370585-26-5C23H20O4
![7,9-Dimethyl-10-phenyl-1,2,3,4-tetrahydro-5H-benzo[c]furo[3,2-g]chromen-5-one chemical structure, C23H20O3, CAS 374764-67-7](/s/SYFJZFJNLLAPAM-UHFFFAOYSA-N.svg)
7,9-Dimethyl-10-phenyl-1,2,3,4-tetrahydro-5H-benzo[c]furo[3,2-g]chromen-5-one
CAS 374764-67-7C23H20O3
![10-(4-Bromophenyl)-7-methyl-1,2,3,4-tetrahydro-5H-benzo[c]furo[3,2-g]chromen-5-one chemical structure, C22H17BrO3, CAS 444996-47-8](/s/CMWWQNFMTXTBPZ-UHFFFAOYSA-N.svg)
10-(4-Bromophenyl)-7-methyl-1,2,3,4-tetrahydro-5H-benzo[c]furo[3,2-g]chromen-5-one
CAS 444996-47-8C22H17BrO3
![10-(4-Bromophenyl)-1,2,3,4-tetrahydro-5H-benzo[c]furo[3,2-g]chromen-5-one chemical structure, C21H15BrO3, CAS 433698-00-1](/s/QKOQDIWTUMYITQ-UHFFFAOYSA-N.svg)
10-(4-Bromophenyl)-1,2,3,4-tetrahydro-5H-benzo[c]furo[3,2-g]chromen-5-one
CAS 433698-00-1C21H15BrO3
![10-(4-Chlorophenyl)-7-methyl-1,2,3,4-tetrahydro-5H-benzo[c]furo[3,2-g]chromen-5-one chemical structure, C22H17ClO3, CAS 374708-26-6](/s/OTBMLMAGENRCHS-UHFFFAOYSA-N.svg)
10-(4-Chlorophenyl)-7-methyl-1,2,3,4-tetrahydro-5H-benzo[c]furo[3,2-g]chromen-5-one
CAS 374708-26-6C22H17ClO3
![10-(3-Fluoro-4-methoxyphenyl)-7-methyl-1,2,3,4-tetrahydro-5H-benzo[c]furo[3,2-g]chromen-5-one chemical structure, C23H19FO4, CAS 374546-69-7](/s/YGNTWLGKFMUUNV-UHFFFAOYSA-N.svg)
10-(3-Fluoro-4-methoxyphenyl)-7-methyl-1,2,3,4-tetrahydro-5H-benzo[c]furo[3,2-g]chromen-5-one
CAS 374546-69-7C23H19FO4
Related scaffolds
Same ring framework with different atoms or bond orders
