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Murcko scaffold

Ring system with 4 rings and 20 atoms

6 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
20
Chemicals
6
With full pages
2
Scaffold SMILES

O=C1CC2OCC3=C(C(=O)c4ccccc4C3=O)C2O1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C1CC2OCC3=C(C(=O)c4ccccc4C3=O)C2O1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 6 of 6 chemicals

Frenolicin B chemical structure, C18H16O6, CAS 68930-68-7
Frenolicin B
CAS 68930-68-7C18H16O6
Kalafungin chemical structure, C16H12O6, CAS 11048-15-0
Kalafungin
CAS 11048-15-0C16H12O6
(11S,15S,17S)-4-Hydroxy-17-methyl-12,16-dioxatetracyclo[8.7.0.03,8.011,15]heptadeca-1(10),3(8),4,6-tetraene-2,9,13-trione chemical structure, C16H12O6, CAS 60325-08-8
(11S,15S,17S)-4-Hydroxy-17-methyl-12,16-dioxatetracyclo[8.7.0.03,8.011,15]heptadeca-1(10),3(8),4,6-tetraene-2,9,13-trione
CAS 60325-08-8C16H12O6
Arizonin B1 chemical structure, C17H14O7, CAS 108890-89-7
Arizonin B1
CAS 108890-89-7C17H14O7
Arizonin A1 chemical structure, C17H14O7, CAS 108890-87-5
Arizonin A1
CAS 108890-87-5C17H14O7
(11S,15S,17S)-4,5-Dimethoxy-17-methyl-12,16-dioxatetracyclo[8.7.0.03,8.011,15]heptadeca-1(10),3(8),4,6-tetraene-2,9,13-trione chemical structure, C18H16O7, CAS 1526958-62-2
(11S,15S,17S)-4,5-Dimethoxy-17-methyl-12,16-dioxatetracyclo[8.7.0.03,8.011,15]heptadeca-1(10),3(8),4,6-tetraene-2,9,13-trione
CAS 1526958-62-2C18H16O7