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Murcko scaffold

4-(Pyridin-3-yl)pyrimidine scaffold

175 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
12
Chemicals
175
With full pages
7
Scaffold SMILES

c1cncc(-c2ccncn2)c1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 4-(Pyridin-3-yl)pyrimidine page
Murcko scaffold c1cncc(-c2ccncn2)c1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 175 chemicals

2-Methyl-6-(pyridin-3-yl)pyrimidin-4-amine chemical structure, C10H10N4, CAS 90916-55-5
2-Methyl-6-(pyridin-3-yl)pyrimidin-4-amine
CAS 90916-55-5C10H10N4
N-(2-Methyl-6-pyridin-3-ylpyrimidin-4-yl)acetamide chemical structure, C12H12N4O, CAS 91560-15-5
N-(2-Methyl-6-pyridin-3-ylpyrimidin-4-yl)acetamide
CAS 91560-15-5C12H12N4O
2-Hydrazino-4-(3-pyridinyl)pyrimidine chemical structure, C9H9N5, CAS 959037-50-4
2-Hydrazino-4-(3-pyridinyl)pyrimidine
CAS 959037-50-4C9H9N5
Methyl 2-(methylsulfanyl)-4-(3-pyridinyl)-5-pyrimidinecarboxylate chemical structure, C12H11N3O2S, CAS 400077-51-2
Methyl 2-(methylsulfanyl)-4-(3-pyridinyl)-5-pyrimidinecarboxylate
CAS 400077-51-2C12H11N3O2S
2-(Methylthio)-4-(pyridin-3-yl)pyrimidine chemical structure, C10H9N3S, CAS 637354-24-6
2-(Methylthio)-4-(pyridin-3-yl)pyrimidine
CAS 637354-24-6C10H9N3S
2-Chloro-4-(6-chloro-3-pyridinyl)pyrimidine chemical structure, C9H5Cl2N3, CAS 475275-74-2
2-Chloro-4-(6-chloro-3-pyridinyl)pyrimidine
CAS 475275-74-2C9H5Cl2N3
2-Chloro-4-(pyridin-3-yl)pyrimidine chemical structure, C9H6ClN3, CAS 483324-01-2
2-Chloro-4-(pyridin-3-yl)pyrimidine
CAS 483324-01-2C9H6ClN3
4-(Pyridin-3-yl)pyrimidin-2-amine chemical structure, C9H8N4, CAS 66521-66-2
4-(Pyridin-3-yl)pyrimidin-2-amine
CAS 66521-66-2C9H8N4
4-(2-Chloropyridin-3-yl)pyrimidine chemical structure, C9H6ClN3, CAS 870221-17-3
4-(2-Chloropyridin-3-yl)pyrimidine
CAS 870221-17-3C9H6ClN3
4-(2-Chloro-3-pyridinyl)-N-methyl-2-pyrimidinamine chemical structure, C10H9ClN4, CAS 870221-22-0
4-(2-Chloro-3-pyridinyl)-N-methyl-2-pyrimidinamine
CAS 870221-22-0C10H9ClN4
4-(2-Fluoropyridin-3-yl)-2-(methylthio)pyrimidine chemical structure, C10H8FN3S, CAS 945375-80-4
4-(2-Fluoropyridin-3-yl)-2-(methylthio)pyrimidine
CAS 945375-80-4C10H8FN3S
4-Methyl-6-(pyridin-3-yl)pyrimidin-2-amine chemical structure, C10H10N4, CAS 90916-52-2
4-Methyl-6-(pyridin-3-yl)pyrimidin-2-amine
CAS 90916-52-2C10H10N4
4-(Pyridin-3-yl)pyrimidine chemical structure, C9H7N3, CAS 98589-71-0
4-(Pyridin-3-yl)pyrimidine
CAS 98589-71-0C9H7N3
N-Methyl-4-(pyridin-3-yl)pyrimidin-2-amine chemical structure, C10H10N4, CAS 1343994-74-0
N-Methyl-4-(pyridin-3-yl)pyrimidin-2-amine
CAS 1343994-74-0C10H10N4
4,5-Pyrimidinediamine, 6-(6-methoxy-2-methyl-3-pyridinyl)- chemical structure, C11H13N5O, CAS 677744-09-1
4,5-Pyrimidinediamine, 6-(6-methoxy-2-methyl-3-pyridinyl)-
CAS 677744-09-1C11H13N5O
4-Chloro-6-(pyridin-3-yl)pyrimidine chemical structure, C9H6ClN3, CAS 954232-31-6
4-Chloro-6-(pyridin-3-yl)pyrimidine
CAS 954232-31-6C9H6ClN3
2,4-Dichloro-6-(3-pyridyl)pyrimidine chemical structure, C9H5Cl2N3, CAS 954232-60-1
2,4-Dichloro-6-(3-pyridyl)pyrimidine
CAS 954232-60-1C9H5Cl2N3
4-Chloro-6-(6-methoxy-3-pyridinyl)pyrimidine chemical structure, C10H8ClN3O, CAS 954218-86-1
4-Chloro-6-(6-methoxy-3-pyridinyl)pyrimidine
CAS 954218-86-1C10H8ClN3O
5-(2-Amino-6-chloro-4-pyrimidinyl)-2-pyridinemethanol chemical structure, C10H9ClN4O, CAS 540753-01-3
5-(2-Amino-6-chloro-4-pyrimidinyl)-2-pyridinemethanol
CAS 540753-01-3C10H9ClN4O
2-Chloro-4-(2-chloropyridin-3-yl)pyrimidine chemical structure, C9H5Cl2N3, CAS 870221-39-9
2-Chloro-4-(2-chloropyridin-3-yl)pyrimidine
CAS 870221-39-9C9H5Cl2N3
2-Chloro-4-(2-fluoropyridin-3-yl)pyrimidine chemical structure, C9H5ClFN3, CAS 954216-54-7
2-Chloro-4-(2-fluoropyridin-3-yl)pyrimidine
CAS 954216-54-7C9H5ClFN3
4-Chloro-6-(6-ethoxy-3-pyridinyl)pyrimidine chemical structure, C11H10ClN3O, CAS 954220-78-1
4-Chloro-6-(6-ethoxy-3-pyridinyl)pyrimidine
CAS 954220-78-1C11H10ClN3O
4-Chloro-6-(2-chloro-pyridin-3-yl)-pyrimidine chemical structure, C9H5Cl2N3, CAS 870221-72-0
4-Chloro-6-(2-chloro-pyridin-3-yl)-pyrimidine
CAS 870221-72-0C9H5Cl2N3
4-Chloro-6-(6-fluoro-5-methyl-3-pyridinyl)pyrimidine chemical structure, C10H7ClFN3, CAS 954223-00-8
4-Chloro-6-(6-fluoro-5-methyl-3-pyridinyl)pyrimidine
CAS 954223-00-8C10H7ClFN3