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Murcko scaffold

Ring system with 4 rings and 23 atoms

33 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
23
Chemicals
33
With full pages
3
Scaffold SMILES

c1ccc(Oc2nnc(-c3ccccc3)c3ccccc23)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold c1ccc(Oc2nnc(-c3ccccc3)c3ccccc23)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 33 of 33 chemicals

1-(2,4-Dichlorophenoxy)-4-(4-fluorophenyl)phthalazine chemical structure, C20H11Cl2FN2O, CAS 314244-48-9
1-(2,4-Dichlorophenoxy)-4-(4-fluorophenyl)phthalazine
CAS 314244-48-9C20H11Cl2FN2O
1-(4-Fluorophenyl)-4-[3-(trifluoromethyl)phenoxy]phthalazine chemical structure, C21H12F4N2O, CAS 670268-53-8
1-(4-Fluorophenyl)-4-[3-(trifluoromethyl)phenoxy]phthalazine
CAS 670268-53-8C21H12F4N2O
4-{[4-(4-Fluorophenyl)phthalazin-1-yl]oxy}benzaldehyde chemical structure, C21H13FN2O2, CAS 326608-23-5
4-{[4-(4-Fluorophenyl)phthalazin-1-yl]oxy}benzaldehyde
CAS 326608-23-5C21H13FN2O2
N-[4-[4-(4-Chlorophenyl)phthalazin-1-yl]oxyphenyl]acetamide chemical structure, C22H16ClN3O2, CAS 361998-36-9
N-[4-[4-(4-Chlorophenyl)phthalazin-1-yl]oxyphenyl]acetamide
CAS 361998-36-9C22H16ClN3O2
N-[3-[4-(4-Methylphenyl)phthalazin-1-yl]oxyphenyl]acetamide chemical structure, C23H19N3O2, CAS 361998-41-6
N-[3-[4-(4-Methylphenyl)phthalazin-1-yl]oxyphenyl]acetamide
CAS 361998-41-6C23H19N3O2
N-(3-{[4-(4-Chlorophenyl)phthalazin-1-yl]oxy}phenyl)acetamide chemical structure, C22H16ClN3O2, CAS 361998-46-1
N-(3-{[4-(4-Chlorophenyl)phthalazin-1-yl]oxy}phenyl)acetamide
CAS 361998-46-1C22H16ClN3O2
N-(3-{[4-(4-Methoxyphenyl)phthalazin-1-yl]oxy}phenyl)acetamide chemical structure, C23H19N3O3, CAS 361998-74-5
N-(3-{[4-(4-Methoxyphenyl)phthalazin-1-yl]oxy}phenyl)acetamide
CAS 361998-74-5C23H19N3O3
1-(4-Methoxyphenyl)-4-(4-methylphenoxy)phthalazine chemical structure, C22H18N2O2, CAS 174542-71-3
1-(4-Methoxyphenyl)-4-(4-methylphenoxy)phthalazine
CAS 174542-71-3C22H18N2O2
1-(4-((4-Phenylphthalazin-1-yl)oxy)phenyl)propan-1-one chemical structure, C23H18N2O2, CAS 379246-14-7
1-(4-((4-Phenylphthalazin-1-yl)oxy)phenyl)propan-1-one
CAS 379246-14-7C23H18N2O2
1-(4-Methoxyphenoxy)-4-(4-methylphenyl)phthalazine chemical structure, C22H18N2O2, CAS 684235-16-3
1-(4-Methoxyphenoxy)-4-(4-methylphenyl)phthalazine
CAS 684235-16-3C22H18N2O2
1-(3-Chloro-4-fluorophenoxy)-4-phenylphthalazine chemical structure, C20H12ClFN2O, CAS 496025-05-9
1-(3-Chloro-4-fluorophenoxy)-4-phenylphthalazine
CAS 496025-05-9C20H12ClFN2O
Diethyl 5-[(4-phenylphthalazin-1-yl)oxy]isophthalate chemical structure, C26H22N2O5, CAS 379245-54-2
Diethyl 5-[(4-phenylphthalazin-1-yl)oxy]isophthalate
CAS 379245-54-2C26H22N2O5
1-(2-Methoxyphenoxy)-4-(4-methylphenyl)phthalazine chemical structure, C22H18N2O2, CAS 379256-15-2
1-(2-Methoxyphenoxy)-4-(4-methylphenyl)phthalazine
CAS 379256-15-2C22H18N2O2
4-{[4-(4-Fluorophenyl)phthalazin-1-yl]oxy}-3-methoxybenzaldehyde chemical structure, C22H15FN2O3, CAS 315691-94-2
4-{[4-(4-Fluorophenyl)phthalazin-1-yl]oxy}-3-methoxybenzaldehyde
CAS 315691-94-2C22H15FN2O3
Methyl 3-[4-(4-fluorophenyl)phthalazinyloxy]benzoate chemical structure, C22H15FN2O3, CAS 307513-41-3
Methyl 3-[4-(4-fluorophenyl)phthalazinyloxy]benzoate
CAS 307513-41-3C22H15FN2O3
3-Methoxy-4-[(4-phenylphthalazin-1-yl)oxy]benzaldehyde chemical structure, C22H16N2O3, CAS 314261-48-8
3-Methoxy-4-[(4-phenylphthalazin-1-yl)oxy]benzaldehyde
CAS 314261-48-8C22H16N2O3
1-(4-Allyl-2-methoxyphenoxy)-4-(p-tolyl)phthalazine chemical structure, C25H22N2O2, CAS 670270-03-8
1-(4-Allyl-2-methoxyphenoxy)-4-(p-tolyl)phthalazine
CAS 670270-03-8C25H22N2O2
Phthalazine, 1-(2-bromophenoxy)-4-phenyl- chemical structure, C20H13BrN2O, CAS 652969-94-3
Phthalazine, 1-(2-bromophenoxy)-4-phenyl-
CAS 652969-94-3C20H13BrN2O
1-(4-Methylphenyl)-4-(4-nitrophenoxy)phthalazine chemical structure, C21H15N3O3, CAS 372495-54-0
1-(4-Methylphenyl)-4-(4-nitrophenoxy)phthalazine
CAS 372495-54-0C21H15N3O3
N-[3-[4-(3,4-Dimethylphenyl)phthalazin-1-yl]oxyphenyl]acetamide chemical structure, C24H21N3O2, CAS 314261-57-9
N-[3-[4-(3,4-Dimethylphenyl)phthalazin-1-yl]oxyphenyl]acetamide
CAS 314261-57-9C24H21N3O2
N-{3-[(4-Phenylphthalazin-1-yl)oxy]phenyl}acetamide chemical structure, C22H17N3O2, CAS 315692-12-7
N-{3-[(4-Phenylphthalazin-1-yl)oxy]phenyl}acetamide
CAS 315692-12-7C22H17N3O2
1-(4-((4-(3,4-Dimethylphenyl)phthalazin-1-yl)oxy)phenyl)propan-1-one chemical structure, C25H22N2O2, CAS 496027-82-8
1-(4-((4-(3,4-Dimethylphenyl)phthalazin-1-yl)oxy)phenyl)propan-1-one
CAS 496027-82-8C25H22N2O2
1-(3,4-Dimethylphenyl)-4-[3-(trifluoromethyl)phenoxy]phthalazine chemical structure, C23H17F3N2O, CAS 670268-38-9
1-(3,4-Dimethylphenyl)-4-[3-(trifluoromethyl)phenoxy]phthalazine
CAS 670268-38-9C23H17F3N2O
(E)-1-(2-Methoxy-4-(prop-1-en-1-yl)phenoxy)-4-(p-tolyl)phthalazine chemical structure, C25H22N2O2, CAS 670270-02-7
(E)-1-(2-Methoxy-4-(prop-1-en-1-yl)phenoxy)-4-(p-tolyl)phthalazine
CAS 670270-02-7C25H22N2O2