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Murcko scaffold

Ring system with 4 rings and 23 atoms

119 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
23
Chemicals
119
With full pages
39
Scaffold SMILES

c1ccc(Nc2nnc(-c3ccccc3)c3ccccc23)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold c1ccc(Nc2nnc(-c3ccccc3)c3ccccc23)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 119 chemicals

MY 5445 chemical structure, C20H14ClN3, CAS 78351-75-4
MY 5445
CAS 78351-75-4C20H14ClN3
4-({4-[4-Methyl-3-(methylsulfamoyl)phenyl]phthalazin-1-yl}amino)benzamide chemical structure, C23H21N5O3S, CAS 333742-01-1
4-({4-[4-Methyl-3-(methylsulfamoyl)phenyl]phthalazin-1-yl}amino)benzamide
CAS 333742-01-1C23H21N5O3S
4-((4-(4-Hydroxyphenyl)phthalazin-1-yl)amino)benzamide chemical structure, C21H16N4O2, CAS 487025-40-1
4-((4-(4-Hydroxyphenyl)phthalazin-1-yl)amino)benzamide
CAS 487025-40-1C21H16N4O2
4-((4-(4-Hydroxyphenyl)phthalazin-1-yl)amino)benzenesulfonamide chemical structure, C20H16N4O3S, CAS 500107-16-4
4-((4-(4-Hydroxyphenyl)phthalazin-1-yl)amino)benzenesulfonamide
CAS 500107-16-4C20H16N4O3S
2-(4-{[4-(4-Hydroxyphenyl)phthalazin-1-yl]amino}phenoxy)acetamide chemical structure, C22H18N4O3, CAS 489416-53-7
2-(4-{[4-(4-Hydroxyphenyl)phthalazin-1-yl]amino}phenoxy)acetamide
CAS 489416-53-7C22H18N4O3
4-{4-[(4-Hydroxyphenyl)amino]phthalazin-1-yl}benzamide chemical structure, C21H16N4O2, CAS 364597-81-9
4-{4-[(4-Hydroxyphenyl)amino]phthalazin-1-yl}benzamide
CAS 364597-81-9C21H16N4O2
4-[4-(4-Sulfamoyl-phenylamino)-phthalazin-1-yl]-benzamide chemical structure, C21H17N5O3S, CAS 375840-32-7
4-[4-(4-Sulfamoyl-phenylamino)-phthalazin-1-yl]-benzamide
CAS 375840-32-7C21H17N5O3S
Methyl 4-((4-(4-hydroxyphenyl)phthalazin-1-yl)amino)benzoate chemical structure, C22H17N3O3, CAS 496799-52-1
Methyl 4-((4-(4-hydroxyphenyl)phthalazin-1-yl)amino)benzoate
CAS 496799-52-1C22H17N3O3
2-[4-[[4-(4-Methoxyphenyl)-1-phthalazinyl]amino]phenyl]acetamide chemical structure, C23H20N4O2, CAS 488861-41-2
2-[4-[[4-(4-Methoxyphenyl)-1-phthalazinyl]amino]phenyl]acetamide
CAS 488861-41-2C23H20N4O2
2-[4-(4-p-Tolyl-phthalazin-1-ylamino)-phenyl]-acetamide chemical structure, C23H20N4O, CAS 510759-96-3
2-[4-(4-p-Tolyl-phthalazin-1-ylamino)-phenyl]-acetamide
CAS 510759-96-3C23H20N4O
N,N,2-trimethyl-5-[4-(4-methylanilino)phthalazin-1-yl]benzenesulfonamide chemical structure, C24H24N4O2S, CAS 364380-91-6
N,N,2-trimethyl-5-[4-(4-methylanilino)phthalazin-1-yl]benzenesulfonamide
CAS 364380-91-6C24H24N4O2S
4-(4-(3-Chlorophenylamino)phthalazin-1-yl)benzamide chemical structure, C21H15ClN4O, CAS 374770-60-2
4-(4-(3-Chlorophenylamino)phthalazin-1-yl)benzamide
CAS 374770-60-2C21H15ClN4O
2-(4-{[4-(4-Methoxyphenyl)phthalazin-1-yl]amino}phenoxy)acetamide chemical structure, C23H20N4O3, CAS 364626-60-8
2-(4-{[4-(4-Methoxyphenyl)phthalazin-1-yl]amino}phenoxy)acetamide
CAS 364626-60-8C23H20N4O3
4-[4-[4-(Diethylcarbamoyl)anilino]phthalazin-1-yl]-N,N-dimethylbenzamide chemical structure, C28H29N5O2, CAS 374922-28-8
4-[4-[4-(Diethylcarbamoyl)anilino]phthalazin-1-yl]-N,N-dimethylbenzamide
CAS 374922-28-8C28H29N5O2
N,N-Diethyl-4-[4-(4-hydroxy-phenylamino)-phthalazin-1-yl]-benzamide chemical structure, C25H24N4O2, CAS 375352-54-8
N,N-Diethyl-4-[4-(4-hydroxy-phenylamino)-phthalazin-1-yl]-benzamide
CAS 375352-54-8C25H24N4O2
Methyl 2-[4-[4-(4-chloroanilino)phthalazin-1-yl]phenoxy]acetate chemical structure, C23H18ClN3O3, CAS 496774-60-8
Methyl 2-[4-[4-(4-chloroanilino)phthalazin-1-yl]phenoxy]acetate
CAS 496774-60-8C23H18ClN3O3
2-[4-({4-[4-Methyl-3-(methylsulfamoyl)phenyl]phthalazin-1-yl}amino)phenyl]acetamide chemical structure, C24H23N5O3S, CAS 510760-01-7
2-[4-({4-[4-Methyl-3-(methylsulfamoyl)phenyl]phthalazin-1-yl}amino)phenyl]acetamide
CAS 510760-01-7C24H23N5O3S
N,N-Diethyl-4-[4-(4-sulfamoylanilino)phthalazin-1-yl]benzamide chemical structure, C25H25N5O3S, CAS 364619-32-9
N,N-Diethyl-4-[4-(4-sulfamoylanilino)phthalazin-1-yl]benzamide
CAS 364619-32-9C25H25N5O3S
N,N-Diethyl-4-(4-(phenylamino)phthalazin-1-yl)benzamide chemical structure, C25H24N4O, CAS 375359-61-8
N,N-Diethyl-4-(4-(phenylamino)phthalazin-1-yl)benzamide
CAS 375359-61-8C25H24N4O
N-[4-[[4-(4-Methyl-3-sulfamoylphenyl)phthalazin-1-yl]amino]phenyl]acetamide chemical structure, C23H21N5O3S, CAS 488100-90-9
N-[4-[[4-(4-Methyl-3-sulfamoylphenyl)phthalazin-1-yl]amino]phenyl]acetamide
CAS 488100-90-9C23H21N5O3S
2-(4-{[4-(4-Methoxyphenyl)phthalazin-1-yl]amino}phenoxy)-N-methylacetamide chemical structure, C24H22N4O3, CAS 374907-89-8
2-(4-{[4-(4-Methoxyphenyl)phthalazin-1-yl]amino}phenoxy)-N-methylacetamide
CAS 374907-89-8C24H22N4O3
4-((4-(4-Hydroxyphenyl)phthalazin-1-yl)amino)-N,N-dimethylbenzamide chemical structure, C23H20N4O2, CAS 497863-82-8
4-((4-(4-Hydroxyphenyl)phthalazin-1-yl)amino)-N,N-dimethylbenzamide
CAS 497863-82-8C23H20N4O2
N,N-Diethyl-4-[4-(4-methylanilino)phthalazin-1-yl]benzamide chemical structure, C26H26N4O, CAS 375358-59-1
N,N-Diethyl-4-[4-(4-methylanilino)phthalazin-1-yl]benzamide
CAS 375358-59-1C26H26N4O
N,N-Diethyl-4-((4-(4-hydroxyphenyl)phthalazin-1-yl)amino)benzamide chemical structure, C25H24N4O2, CAS 510759-82-7
N,N-Diethyl-4-((4-(4-hydroxyphenyl)phthalazin-1-yl)amino)benzamide
CAS 510759-82-7C25H24N4O2