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Murcko scaffold

Ring system with 2 rings and 14 atoms

37 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
14
Chemicals
37
With full pages
4
Scaffold SMILES

c1ccc(CCc2ncccn2)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold c1ccc(CCc2ncccn2)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 37 of 37 chemicals

2-(3-Chlorophenethyl)-4,6-dichloropyrimidine chemical structure, C12H9Cl3N2, CAS 321329-30-0
2-(3-Chlorophenethyl)-4,6-dichloropyrimidine
CAS 321329-30-0C12H9Cl3N2
2-(2-Phenylethyl)pyrimidine-5-carboxylic acid chemical structure, C13H12N2O2, CAS 1092291-49-0
2-(2-Phenylethyl)pyrimidine-5-carboxylic acid
CAS 1092291-49-0C13H12N2O2
2-Phenyl-1-(pyrimidin-2-yl)ethanamine chemical structure, C12H13N3, CAS 1184266-01-0
2-Phenyl-1-(pyrimidin-2-yl)ethanamine
CAS 1184266-01-0C12H13N3
2-(3-Chlorophenyl)-1-(pyrimidin-2-yl)ethan-1-amine chemical structure, C12H12ClN3, CAS 1183780-05-3
2-(3-Chlorophenyl)-1-(pyrimidin-2-yl)ethan-1-amine
CAS 1183780-05-3C12H12ClN3
2-(4-Fluorophenyl)-1-(pyrimidin-2-yl)ethan-1-amine chemical structure, C12H12FN3, CAS 1179881-03-8
2-(4-Fluorophenyl)-1-(pyrimidin-2-yl)ethan-1-amine
CAS 1179881-03-8C12H12FN3
4-Chloro-2-(2-phenylethyl)pyrimidine chemical structure, C12H11ClN2, CAS 1251075-55-4
4-Chloro-2-(2-phenylethyl)pyrimidine
CAS 1251075-55-4C12H11ClN2
2-Phenethylpyrimidin-4-amine chemical structure, C12H13N3, CAS 1248741-22-1
2-Phenethylpyrimidin-4-amine
CAS 1248741-22-1C12H13N3
[2-(2-Phenylethyl)pyrimidin-4-yl]methanol chemical structure, C13H14N2O, CAS 1343033-17-9
[2-(2-Phenylethyl)pyrimidin-4-yl]methanol
CAS 1343033-17-9C13H14N2O
4,6-Dichloro-2-(2-phenylethyl)-5-propylpyrimidine chemical structure, C15H16Cl2N2, CAS 88945-23-7
4,6-Dichloro-2-(2-phenylethyl)-5-propylpyrimidine
CAS 88945-23-7C15H16Cl2N2
4,6-Dichloro-5-pentyl-2-(2-phenylethyl)pyrimidine chemical structure, C17H20Cl2N2, CAS 88945-24-8
4,6-Dichloro-5-pentyl-2-(2-phenylethyl)pyrimidine
CAS 88945-24-8C17H20Cl2N2
4,6-Dichloro-2-[2-(4-methoxyphenyl)ethyl]-5-pentylpyrimidine chemical structure, C18H22Cl2N2O, CAS 88945-25-9
4,6-Dichloro-2-[2-(4-methoxyphenyl)ethyl]-5-pentylpyrimidine
CAS 88945-25-9C18H22Cl2N2O
2-(2-Phenylethyl)-5-propylpyrimidine chemical structure, C15H18N2, CAS 88945-26-0
2-(2-Phenylethyl)-5-propylpyrimidine
CAS 88945-26-0C15H18N2
4-[2-(5-Pentylpyrimidin-2-yl)ethyl]phenol chemical structure, C17H22N2O, CAS 88945-27-1
4-[2-(5-Pentylpyrimidin-2-yl)ethyl]phenol
CAS 88945-27-1C17H22N2O
2-[2-(4-Methoxyphenyl)ethyl]-5-pentylpyrimidine chemical structure, C18H24N2O, CAS 88945-28-2
2-[2-(4-Methoxyphenyl)ethyl]-5-pentylpyrimidine
CAS 88945-28-2C18H24N2O
2-[2-(4-Ethoxyphenyl)ethyl]-5-pentylpyrimidine chemical structure, C19H26N2O, CAS 88945-29-3
2-[2-(4-Ethoxyphenyl)ethyl]-5-pentylpyrimidine
CAS 88945-29-3C19H26N2O
2-[2-(4-Butoxyphenyl)ethyl]-5-pentylpyrimidine chemical structure, C21H30N2O, CAS 88945-30-6
2-[2-(4-Butoxyphenyl)ethyl]-5-pentylpyrimidine
CAS 88945-30-6C21H30N2O
2-{2-[4-(Hexyloxy)phenyl]ethyl}-5-pentylpyrimidine chemical structure, C23H34N2O, CAS 88945-31-7
2-{2-[4-(Hexyloxy)phenyl]ethyl}-5-pentylpyrimidine
CAS 88945-31-7C23H34N2O
4-(2-(5-Propylpyrimidin-2-yl)ethyl)benzamide chemical structure, C16H19N3O, CAS 88945-32-8
4-(2-(5-Propylpyrimidin-2-yl)ethyl)benzamide
CAS 88945-32-8C16H19N3O
4-(2-(5-Pentylpyrimidin-2-yl)ethyl)benzamide chemical structure, C18H23N3O, CAS 88945-33-9
4-(2-(5-Pentylpyrimidin-2-yl)ethyl)benzamide
CAS 88945-33-9C18H23N3O
4-[2-(5-Propylpyrimidin-2-yl)ethyl]benzonitrile chemical structure, C16H17N3, CAS 88945-34-0
4-[2-(5-Propylpyrimidin-2-yl)ethyl]benzonitrile
CAS 88945-34-0C16H17N3
4-[2-(5-Pentylpyrimidin-2-yl)ethyl]benzonitrile chemical structure, C18H21N3, CAS 88945-35-1
4-[2-(5-Pentylpyrimidin-2-yl)ethyl]benzonitrile
CAS 88945-35-1C18H21N3
4-[2-(Pyrimidin-2-yl)ethyl]benzonitrile chemical structure, C13H11N3, CAS 89013-04-7
4-[2-(Pyrimidin-2-yl)ethyl]benzonitrile
CAS 89013-04-7C13H11N3
4-[2-Amino-2-(pyrimidin-2-yl)ethyl]phenol chemical structure, C12H13N3O, CAS 1500613-96-6
4-[2-Amino-2-(pyrimidin-2-yl)ethyl]phenol
CAS 1500613-96-6C12H13N3O
2-(2,4-Difluorophenyl)-1-(5-methylpyrimidin-2-yl)ethan-1-amine chemical structure, C13H13F2N3, CAS 1545914-62-2
2-(2,4-Difluorophenyl)-1-(5-methylpyrimidin-2-yl)ethan-1-amine
CAS 1545914-62-2C13H13F2N3