CompoundList
Sign in
Murcko scaffold

Ring system with 3 rings and 16 atoms

6 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
16
Chemicals
6
With full pages
1
Scaffold SMILES

c1ccc(CC2CC2c2ccncc2)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold c1ccc(CC2CC2c2ccncc2)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 6 of 6 chemicals

Phenyl[2-(pyridin-4-yl)cyclopropyl]methanamine hydrochloride chemical structure, C15H17ClN2, CAS 2241130-38-9
Phenyl[2-(pyridin-4-yl)cyclopropyl]methanamine hydrochloride
CAS 2241130-38-9C15H17ClN2
1-Phenyl-1-[2-(pyridin-4-yl)cyclopropyl]methanamine chemical structure, C15H16N2, CAS 2241130-37-8
1-Phenyl-1-[2-(pyridin-4-yl)cyclopropyl]methanamine
CAS 2241130-37-8C15H16N2
N-[Phenyl-(2-pyridin-4-ylcyclopropyl)methyl]prop-2-enamide chemical structure, C18H18N2O, CAS 2411274-91-2
N-[Phenyl-(2-pyridin-4-ylcyclopropyl)methyl]prop-2-enamide
CAS 2411274-91-2C18H18N2O
(E)-4-(Dimethylamino)-N-[phenyl-(2-pyridin-4-ylcyclopropyl)methyl]but-2-enamide chemical structure, C21H25N3O, CAS 2411333-19-0
(E)-4-(Dimethylamino)-N-[phenyl-(2-pyridin-4-ylcyclopropyl)methyl]but-2-enamide
CAS 2411333-19-0C21H25N3O
N-{Phenyl[2-(pyridin-4-yl)cyclopropyl]methyl}but-2-ynamide chemical structure, C19H18N2O, CAS 2411308-45-5
N-{Phenyl[2-(pyridin-4-yl)cyclopropyl]methyl}but-2-ynamide
CAS 2411308-45-5C19H18N2O
2-Chloro-N-{phenyl[2-(pyridin-4-yl)cyclopropyl]methyl}acetamide hydrochloride chemical structure, C17H18Cl2N2O, CAS 2411243-88-2
2-Chloro-N-{phenyl[2-(pyridin-4-yl)cyclopropyl]methyl}acetamide hydrochloride
CAS 2411243-88-2C17H18Cl2N2O