Murcko scaffold
3-Azabicyclo[3.1.0]hexan-3-yl(phenyl)methanone scaffold
31 chemicals on CompoundList share this ring system.
- Rings
- 3
- Scaffold atoms
- 14
- Chemicals
- 31
- With full pages
- 2
Scaffold SMILES
O=C(c1ccccc1)N1CC2CC2C1
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 31 of 31 chemicals
![3-(3-Methoxybenzoyl)-3-azabicyclo[3.1.0]hexane-2-carboxylic acid chemical structure, C14H15NO4, CAS 1009708-17-1](/s/QACJHRLGLSVZIU-UHFFFAOYSA-N.svg)
3-(3-Methoxybenzoyl)-3-azabicyclo[3.1.0]hexane-2-carboxylic acid
CAS 1009708-17-1C14H15NO4
![3-(2,4-Dichlorobenzoyl)-3-azabicyclo[3.1.0]hexane-2-carboxylic acid chemical structure, C13H11Cl2NO3, CAS 1009716-18-0](/s/PPJAJGGQNARTGA-UHFFFAOYSA-N.svg)
3-(2,4-Dichlorobenzoyl)-3-azabicyclo[3.1.0]hexane-2-carboxylic acid
CAS 1009716-18-0C13H11Cl2NO3
![3-[3-(Trifluoromethyl)benzoyl]-3-azabicyclo[3.1.0]hexane-2-carboxylic acid chemical structure, C14H12F3NO3, CAS 1009510-15-9](/s/STJKIRXHQHUNJJ-UHFFFAOYSA-N.svg)
3-[3-(Trifluoromethyl)benzoyl]-3-azabicyclo[3.1.0]hexane-2-carboxylic acid
CAS 1009510-15-9C14H12F3NO3
![3-(4-Fluorobenzoyl)-3-azabicyclo[3.1.0]hexane-2-carboxylic acid chemical structure, C13H12FNO3, CAS 1009353-30-3](/s/GDVQTWSMSQVCRX-UHFFFAOYSA-N.svg)
3-(4-Fluorobenzoyl)-3-azabicyclo[3.1.0]hexane-2-carboxylic acid
CAS 1009353-30-3C13H12FNO3
![3-(4-Chlorobenzoyl)-3-azabicyclo[3.1.0]hexane-2-carboxylic acid chemical structure, C13H12ClNO3, CAS 1009353-35-8](/s/WPDMRWXINIYZKY-UHFFFAOYSA-N.svg)
3-(4-Chlorobenzoyl)-3-azabicyclo[3.1.0]hexane-2-carboxylic acid
CAS 1009353-35-8C13H12ClNO3
![(1S,2S,5R)-3-(2-Fluorobenzoyl)-3-azabicyclo[3.1.0]hexane-2-carboxylic acid chemical structure, C13H12FNO3, CAS 1173667-00-9](/s/BVVKPJIGNVJQBD-ARENWVFISA-N.svg)
(1S,2S,5R)-3-(2-Fluorobenzoyl)-3-azabicyclo[3.1.0]hexane-2-carboxylic acid
CAS 1173667-00-9C13H12FNO3
![3-Azabicyclo[3.1.0]hexan-3-yl(2-bromophenyl)methanone chemical structure, C12H12BrNO, CAS 1787797-54-9](/s/OPGQTEIEYVWZGE-UHFFFAOYSA-N.svg)
3-Azabicyclo[3.1.0]hexan-3-yl(2-bromophenyl)methanone
CAS 1787797-54-9C12H12BrNO
![3-Azabicyclo[3.1.0]hexan-3-yl(4-bromophenyl)methanone chemical structure, C12H12BrNO, CAS 1786274-66-5](/s/CSSHUQHDUPIPTF-UHFFFAOYSA-N.svg)
3-Azabicyclo[3.1.0]hexan-3-yl(4-bromophenyl)methanone
CAS 1786274-66-5C12H12BrNO
![3-Azabicyclo[3.1.0]hexan-3-yl(3-bromophenyl)methanone chemical structure, C12H12BrNO, CAS 1789305-45-8](/s/DKYFCDNMLOBVRX-UHFFFAOYSA-N.svg)
3-Azabicyclo[3.1.0]hexan-3-yl(3-bromophenyl)methanone
CAS 1789305-45-8C12H12BrNO
![3-Azabicyclo[3.1.0]hexan-3-yl(phenyl)methanone chemical structure, C12H13NO, CAS 1789842-07-4](/s/PZWNQSJXMXNUAT-UHFFFAOYSA-N.svg)
3-Azabicyclo[3.1.0]hexan-3-yl(phenyl)methanone
CAS 1789842-07-4C12H13NO
![3-Azabicyclo[3.1.0]hexan-3-yl(4-iodophenyl)methanone chemical structure, C12H12INO, CAS 1854261-20-3](/s/CLSQVCIEHKPAFZ-UHFFFAOYSA-N.svg)
3-Azabicyclo[3.1.0]hexan-3-yl(4-iodophenyl)methanone
CAS 1854261-20-3C12H12INO
![3-Azabicyclo[3.1.0]hexan-3-yl(3-iodophenyl)methanone chemical structure, C12H12INO, CAS 1859319-48-4](/s/LHZZUMWOJIDRJY-UHFFFAOYSA-N.svg)
3-Azabicyclo[3.1.0]hexan-3-yl(3-iodophenyl)methanone
CAS 1859319-48-4C12H12INO
![6,6-Difluoro-3-[4-(trifluoromethyl)benzoyl]-3-azabicyclo[3.1.0]hexane chemical structure, C13H10F5NO, CAS 2137671-72-6](/s/JMJJQODYVBEELK-UHFFFAOYSA-N.svg)
6,6-Difluoro-3-[4-(trifluoromethyl)benzoyl]-3-azabicyclo[3.1.0]hexane
CAS 2137671-72-6C13H10F5NO
![tert-Butyl N-[(1R,5S,6R)-3-[4-(prop-2-enamido)benzoyl]-3-azabicyclo[3.1.0]hexan-6-yl]carbamate chemical structure, C20H25N3O4, CAS 2411177-74-5](/s/MUGIIWZSTREBKO-FKEKPDDDSA-N.svg)
tert-Butyl N-[(1R,5S,6R)-3-[4-(prop-2-enamido)benzoyl]-3-azabicyclo[3.1.0]hexan-6-yl]carbamate
CAS 2411177-74-5C20H25N3O4
![3-Azabicyclo[3.1.0]hexan-3-yl(2-bromo-4-methylphenyl)methanone chemical structure, C13H14BrNO, CAS 1854463-59-4](/s/HPWNKWSAGVCFPE-UHFFFAOYSA-N.svg)
3-Azabicyclo[3.1.0]hexan-3-yl(2-bromo-4-methylphenyl)methanone
CAS 1854463-59-4C13H14BrNO
![3-Azabicyclo[3.1.0]hexan-3-yl(2-bromo-4-methoxyphenyl)methanone chemical structure, C13H14BrNO2, CAS 2990093-36-0](/s/BWHIXXBTUSMJSP-UHFFFAOYSA-N.svg)
3-Azabicyclo[3.1.0]hexan-3-yl(2-bromo-4-methoxyphenyl)methanone
CAS 2990093-36-0C13H14BrNO2
![3-Azabicyclo[3.1.0]hexan-3-yl(2-bromo-4-chlorophenyl)methanone chemical structure, C12H11BrClNO, CAS 1852798-53-8](/s/FKJGYHNRVNHZCK-UHFFFAOYSA-N.svg)
3-Azabicyclo[3.1.0]hexan-3-yl(2-bromo-4-chlorophenyl)methanone
CAS 1852798-53-8C12H11BrClNO
![3-Azabicyclo[3.1.0]hexan-3-yl(2-bromo-4-fluorophenyl)methanone chemical structure, C12H11BrFNO, CAS 1854442-22-0](/s/KDJCHQHMOCWCQH-UHFFFAOYSA-N.svg)
3-Azabicyclo[3.1.0]hexan-3-yl(2-bromo-4-fluorophenyl)methanone
CAS 1854442-22-0C12H11BrFNO
![3-Azabicyclo[3.1.0]hexan-3-yl(4-bromo-2-methylphenyl)methanone chemical structure, C13H14BrNO, CAS 2990839-62-6](/s/MUKFWIBRTIZQIS-UHFFFAOYSA-N.svg)
3-Azabicyclo[3.1.0]hexan-3-yl(4-bromo-2-methylphenyl)methanone
CAS 2990839-62-6C13H14BrNO
![3-Azabicyclo[3.1.0]hexan-3-yl(4-bromo-2-iodophenyl)methanone chemical structure, C12H11BrINO, CAS 2990238-94-1](/s/GDOKTZSPEACFHK-UHFFFAOYSA-N.svg)
3-Azabicyclo[3.1.0]hexan-3-yl(4-bromo-2-iodophenyl)methanone
CAS 2990238-94-1C12H11BrINO
![3-Azabicyclo[3.1.0]hexan-3-yl(4-bromo-2-chlorophenyl)methanone chemical structure, C12H11BrClNO, CAS 2990385-86-7](/s/ZTJDYYDLJFWNRQ-UHFFFAOYSA-N.svg)
3-Azabicyclo[3.1.0]hexan-3-yl(4-bromo-2-chlorophenyl)methanone
CAS 2990385-86-7C12H11BrClNO
![3-Azabicyclo[3.1.0]hexan-3-yl(4-bromo-2-fluorophenyl)methanone chemical structure, C12H11BrFNO, CAS 1866081-94-8](/s/YLOLOHQKCPDDOM-UHFFFAOYSA-N.svg)
3-Azabicyclo[3.1.0]hexan-3-yl(4-bromo-2-fluorophenyl)methanone
CAS 1866081-94-8C12H11BrFNO
![3-Azabicyclo[3.1.0]hexan-3-yl(4-bromo-2-methoxyphenyl)methanone chemical structure, C13H14BrNO2, CAS 2028891-09-8](/s/RNLZYMNDSAYYHA-UHFFFAOYSA-N.svg)
3-Azabicyclo[3.1.0]hexan-3-yl(4-bromo-2-methoxyphenyl)methanone
CAS 2028891-09-8C13H14BrNO2
![3-Azabicyclo[3.1.0]hexan-3-yl(4-bromo-3-methylphenyl)methanone chemical structure, C13H14BrNO, CAS 1865313-05-8](/s/KATVRFUVSQIIJW-UHFFFAOYSA-N.svg)
3-Azabicyclo[3.1.0]hexan-3-yl(4-bromo-3-methylphenyl)methanone
CAS 1865313-05-8C13H14BrNO
- 3-Azabicyclo[3.1.0]hexan-3-yl(4-bromo-3-fluorophenyl)methanone1859742-48-5C12H11BrFNO
- 3-Azabicyclo[3.1.0]hexan-3-yl(4-bromo-3-chlorophenyl)methanone1854442-25-3C12H11BrClNO
- 3-Azabicyclo[3.1.0]hexan-3-yl(4-bromo-3-methoxyphenyl)methanone2989408-05-9C13H14BrNO2
- 3-Azabicyclo[3.1.0]hexan-3-yl(4-ethynylphenyl)methanone3078398-12-3C14H13NO
- 3-Azabicyclo[3.1.0]hexan-3-yl(3-ethynylphenyl)methanone3078384-20-7C14H13NO
- 3-(3,4,5-Trimethoxybenzoyl)-3-azabicyclo[3.1.0]hexane-1,5-dicarboxylic acid2467819-26-5C17H19NO8
- (6,6-Difluoro-3-azabicyclo[3.1.0]hexan-3-yl)-phenylmethanone2160847-00-5C12H11F2NO
Related scaffolds
Same ring framework with different atoms or bond orders
