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Murcko scaffold

Ring system with 4 rings and 23 atoms

6 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
23
Chemicals
6
With full pages
4
Scaffold SMILES

O=c1cc(-c2ccccc2)oc2c(C3CCNCC3)cccc12

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=c1cc(-c2ccccc2)oc2c(C3CCNCC3)cccc12

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 6 of 6 chemicals

Alvocidib chemical structure, C21H20ClNO5, CAS 146426-40-6
Alvocidib
CAS 146426-40-6C21H20ClNO5
2-(2-Chlorophenyl)-5,7-dihydroxy-8-(3-hydroxy-1-methylpiperidin-4-yl)chromen-4-one chemical structure, C21H20ClNO5, CAS 810696-13-0
2-(2-Chlorophenyl)-5,7-dihydroxy-8-(3-hydroxy-1-methylpiperidin-4-yl)chromen-4-one
CAS 810696-13-0C21H20ClNO5
Flavopiridol hydrochloride chemical structure, C21H21Cl2NO5, CAS 131740-09-5
Flavopiridol hydrochloride
CAS 131740-09-5C21H21Cl2NO5
(3S,4R)-2-(2-Chlorophenyl)-8-(3-hydroxy-1-methyl-4-piperidinyl)-5,7-dimethoxy-4H-1-benzopyran-4-one chemical structure, C23H24ClNO5, CAS 199589-13-4
(3S,4R)-2-(2-Chlorophenyl)-8-(3-hydroxy-1-methyl-4-piperidinyl)-5,7-dimethoxy-4H-1-benzopyran-4-one
CAS 199589-13-4C23H24ClNO5
Tp-1287 chemical structure, C21H21ClNO8P, CAS 2044686-42-0
Tp-1287
CAS 2044686-42-0C21H21ClNO8P
2-(2-Fluorophenyl)-5,7-dihydroxy-8-((3S,4R)-3-hydroxy-1-methylpiperidin-4-yl)-4H-chromen-4-one hydrochloride chemical structure, C21H21ClFNO5, CAS 1271744-68-3
2-(2-Fluorophenyl)-5,7-dihydroxy-8-((3S,4R)-3-hydroxy-1-methylpiperidin-4-yl)-4H-chromen-4-one hydrochloride
CAS 1271744-68-3C21H21ClFNO5