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Murcko scaffold

6-(Phenoxymethyl)-3-pyridin-2-yl-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole scaffold

18 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
22
Chemicals
18
With full pages
2
Scaffold SMILES

c1ccc(OCc2nn3c(-c4ccccn4)nnc3s2)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 6-(Phenoxymethyl)-3-pyridin-2-yl-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole page
Murcko scaffold c1ccc(OCc2nn3c(-c4ccccn4)nnc3s2)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 18 of 18 chemicals

6-(Phenoxymethyl)-3-pyridin-2-yl-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole chemical structure, C15H11N5OS, CAS 840512-53-0
6-(Phenoxymethyl)-3-pyridin-2-yl-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole
CAS 840512-53-0C15H11N5OS
6-[(4-Methoxyphenoxy)methyl]-3-pyridin-2-yl-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole chemical structure, C16H13N5O2S, CAS 877805-05-5
6-[(4-Methoxyphenoxy)methyl]-3-pyridin-2-yl-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole
CAS 877805-05-5C16H13N5O2S
6-[(4-Chlorophenoxy)methyl]-3-pyridin-2-yl-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole chemical structure, C15H10ClN5OS, CAS 849915-90-8
6-[(4-Chlorophenoxy)methyl]-3-pyridin-2-yl-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole
CAS 849915-90-8C15H10ClN5OS
6-[(4-Methylphenoxy)methyl]-3-(2-pyridinyl)[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole chemical structure, C16H13N5OS, CAS 862199-66-4
6-[(4-Methylphenoxy)methyl]-3-(2-pyridinyl)[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole
CAS 862199-66-4C16H13N5OS
6-{[5-Methyl-2-(propan-2-yl)phenoxy]methyl}-3-(pyridin-2-yl)[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole chemical structure, C19H19N5OS, CAS 929967-20-4
6-{[5-Methyl-2-(propan-2-yl)phenoxy]methyl}-3-(pyridin-2-yl)[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole
CAS 929967-20-4C19H19N5OS
2,6-Dimethylphenyl [3-(2-pyridinyl)[1,2,4]triazolo[3,4-b][1,3,4]thiadiazol-6-yl]methyl ether chemical structure, C17H15N5OS, CAS 929812-07-7
2,6-Dimethylphenyl [3-(2-pyridinyl)[1,2,4]triazolo[3,4-b][1,3,4]thiadiazol-6-yl]methyl ether
CAS 929812-07-7C17H15N5OS
6-[(2-Methylphenoxy)methyl]-3-(2-pyridinyl)[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole chemical structure, C16H13N5OS, CAS 947027-27-2
6-[(2-Methylphenoxy)methyl]-3-(2-pyridinyl)[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole
CAS 947027-27-2C16H13N5OS
3,4-Dimethylphenyl [3-(2-pyridinyl)[1,2,4]triazolo[3,4-b][1,3,4]thiadiazol-6-yl]methyl ether chemical structure, C17H15N5OS, CAS 947864-77-9
3,4-Dimethylphenyl [3-(2-pyridinyl)[1,2,4]triazolo[3,4-b][1,3,4]thiadiazol-6-yl]methyl ether
CAS 947864-77-9C17H15N5OS
4-tert-Butylphenyl [3-(2-pyridinyl)[1,2,4]triazolo[3,4-b][1,3,4]thiadiazol-6-yl]methyl ether chemical structure, C19H19N5OS, CAS 947930-34-9
4-tert-Butylphenyl [3-(2-pyridinyl)[1,2,4]triazolo[3,4-b][1,3,4]thiadiazol-6-yl]methyl ether
CAS 947930-34-9C19H19N5OS
6-[(2-Chlorophenoxy)methyl]-3-(2-pyridinyl)[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole chemical structure, C15H10ClN5OS, CAS 947883-78-5
6-[(2-Chlorophenoxy)methyl]-3-(2-pyridinyl)[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole
CAS 947883-78-5C15H10ClN5OS
6-[(3-Methylphenoxy)methyl]-3-(2-pyridinyl)[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole chemical structure, C16H13N5OS, CAS 947883-76-3
6-[(3-Methylphenoxy)methyl]-3-(2-pyridinyl)[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole
CAS 947883-76-3C16H13N5OS
6-[(4-Bromophenoxy)methyl]-3-(2-pyridinyl)[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole chemical structure, C15H10BrN5OS, CAS 947027-31-8
6-[(4-Bromophenoxy)methyl]-3-(2-pyridinyl)[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole
CAS 947027-31-8C15H10BrN5OS
2,4-Dichlorophenyl [3-(2-pyridinyl)[1,2,4]triazolo[3,4-b][1,3,4]thiadiazol-6-yl]methyl ether chemical structure, C15H9Cl2N5OS, CAS 947864-80-4
2,4-Dichlorophenyl [3-(2-pyridinyl)[1,2,4]triazolo[3,4-b][1,3,4]thiadiazol-6-yl]methyl ether
CAS 947864-80-4C15H9Cl2N5OS
6-[(4-Fluorophenoxy)methyl]-3-(2-pyridinyl)[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole chemical structure, C15H10FN5OS, CAS 947930-37-2
6-[(4-Fluorophenoxy)methyl]-3-(2-pyridinyl)[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole
CAS 947930-37-2C15H10FN5OS
6-[(2-Methoxyphenoxy)methyl]-3-(2-pyridinyl)[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole chemical structure, C16H13N5O2S, CAS 947027-35-2
6-[(2-Methoxyphenoxy)methyl]-3-(2-pyridinyl)[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole
CAS 947027-35-2C16H13N5O2S
6-[(3-Methoxyphenoxy)methyl]-3-pyridin-2-yl-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole chemical structure, C16H13N5O2S, CAS 947883-81-0
6-[(3-Methoxyphenoxy)methyl]-3-pyridin-2-yl-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole
CAS 947883-81-0C16H13N5O2S
6-[(2-Ethoxyphenoxy)methyl]-3-(2-pyridinyl)[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole chemical structure, C17H15N5O2S, CAS 947864-83-7
6-[(2-Ethoxyphenoxy)methyl]-3-(2-pyridinyl)[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole
CAS 947864-83-7C17H15N5O2S
6-(1-Phenoxyethyl)-3-pyridin-2-yl-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole chemical structure, C16H13N5OS, CAS 947883-84-3
6-(1-Phenoxyethyl)-3-pyridin-2-yl-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole
CAS 947883-84-3C16H13N5OS