CompoundList
Sign in
Murcko scaffold

Ring system with 4 rings and 22 atoms

11 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
22
Chemicals
11
With full pages
1
Scaffold SMILES

c1ccc(CCc2nn3c(-c4ccccc4)nnc3s2)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold c1ccc(CCc2nn3c(-c4ccccc4)nnc3s2)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 11 of 11 chemicals

3-(4-Fluorophenyl)-6-(2-phenylethyl)[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole chemical structure, C17H13FN4S, CAS 724432-38-6
3-(4-Fluorophenyl)-6-(2-phenylethyl)[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole
CAS 724432-38-6C17H13FN4S
3-(4-Methylphenyl)-6-(2-phenylethyl)[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole chemical structure, C18H16N4S, CAS 193744-08-0
3-(4-Methylphenyl)-6-(2-phenylethyl)[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole
CAS 193744-08-0C18H16N4S
3-(2-Methoxyphenyl)-6-(2-phenylethyl)[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole chemical structure, C18H16N4OS, CAS 791824-17-4
3-(2-Methoxyphenyl)-6-(2-phenylethyl)[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole
CAS 791824-17-4C18H16N4OS
3-(2-Bromophenyl)-6-(2-phenylethyl)[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole chemical structure, C17H13BrN4S, CAS 831245-24-0
3-(2-Bromophenyl)-6-(2-phenylethyl)[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole
CAS 831245-24-0C17H13BrN4S
3-(3,4-Dimethoxyphenyl)-6-(2-phenylethyl)[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole chemical structure, C19H18N4O2S, CAS 878430-22-9
3-(3,4-Dimethoxyphenyl)-6-(2-phenylethyl)[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole
CAS 878430-22-9C19H18N4O2S
3-(4-Methoxyphenyl)-6-(2-phenylethyl)[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole chemical structure, C18H16N4OS, CAS 895333-79-6
3-(4-Methoxyphenyl)-6-(2-phenylethyl)[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole
CAS 895333-79-6C18H16N4OS
3-(3-Chlorophenyl)-6-[2-(3,4-dimethoxyphenyl)ethyl][1,2,4]triazolo[3,4-b][1,3,4]thiadiazole chemical structure, C19H17ClN4O2S, CAS 951996-07-9
3-(3-Chlorophenyl)-6-[2-(3,4-dimethoxyphenyl)ethyl][1,2,4]triazolo[3,4-b][1,3,4]thiadiazole
CAS 951996-07-9C19H17ClN4O2S
3-(4-Bromophenyl)-6-[2-(3,4-dimethoxyphenyl)ethyl][1,2,4]triazolo[3,4-b][1,3,4]thiadiazole chemical structure, C19H17BrN4O2S, CAS 951934-59-1
3-(4-Bromophenyl)-6-[2-(3,4-dimethoxyphenyl)ethyl][1,2,4]triazolo[3,4-b][1,3,4]thiadiazole
CAS 951934-59-1C19H17BrN4O2S
3-(3-Bromophenyl)-6-[2-(3,4-dimethoxyphenyl)ethyl][1,2,4]triazolo[3,4-b][1,3,4]thiadiazole chemical structure, C19H17BrN4O2S, CAS 951977-11-0
3-(3-Bromophenyl)-6-[2-(3,4-dimethoxyphenyl)ethyl][1,2,4]triazolo[3,4-b][1,3,4]thiadiazole
CAS 951977-11-0C19H17BrN4O2S
6-[2-(3,4-Dimethoxyphenyl)ethyl]-3-(4-fluorophenyl)[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole chemical structure, C19H17FN4O2S, CAS 951924-31-5
6-[2-(3,4-Dimethoxyphenyl)ethyl]-3-(4-fluorophenyl)[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole
CAS 951924-31-5C19H17FN4O2S
3-(4-Chlorophenyl)-6-[2-(3,4-dimethoxyphenyl)ethyl][1,2,4]triazolo[3,4-b][1,3,4]thiadiazole chemical structure, C19H17ClN4O2S, CAS 951957-24-7
3-(4-Chlorophenyl)-6-[2-(3,4-dimethoxyphenyl)ethyl][1,2,4]triazolo[3,4-b][1,3,4]thiadiazole
CAS 951957-24-7C19H17ClN4O2S