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Murcko scaffold

Ring system with 3 rings and 15 atoms

22 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
15
Chemicals
22
With full pages
3
Scaffold SMILES

O=c1[nH]c2cncnc2n1C1CCCO1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=c1[nH]c2cncnc2n1C1CCCO1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 22 of 22 chemicals

8-Oxoadenosine chemical structure, C10H13N5O5, CAS 29851-57-8
8-Oxoadenosine
CAS 29851-57-8C10H13N5O5
2'-Deoxy-7,8-dihydro-8-oxoadenosine chemical structure, C10H13N5O4, CAS 62471-63-0
2'-Deoxy-7,8-dihydro-8-oxoadenosine
CAS 62471-63-0C10H13N5O4
8-Hydroxyadenosine 5'-triphosphate chemical structure, C10H16N5O14P3, CAS 68745-44-8
8-Hydroxyadenosine 5'-triphosphate
CAS 68745-44-8C10H16N5O14P3
8-Hydroxyadenosine 5'-monophosphate chemical structure, C10H14N5O8P, CAS 25030-04-0
8-Hydroxyadenosine 5'-monophosphate
CAS 25030-04-0C10H14N5O8P
N-[9-[3,4-Dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-8-oxo-7H-purin-6-yl]acetamide chemical structure, C12H15N5O6, CAS 3868-35-7
N-[9-[3,4-Dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-8-oxo-7H-purin-6-yl]acetamide
CAS 3868-35-7C12H15N5O6
6-Amino-7-methyl-9-pentofuranosyl-7,9-dihydro-8H-purin-8-one chemical structure, C11H15N5O5, CAS 27963-79-7
6-Amino-7-methyl-9-pentofuranosyl-7,9-dihydro-8H-purin-8-one
CAS 27963-79-7C11H15N5O5
6-Amino-9-[3-azido-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-7H-purin-8-one chemical structure, C10H12N8O4, CAS 64864-70-6
6-Amino-9-[3-azido-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-7H-purin-8-one
CAS 64864-70-6C10H12N8O4
Phosmidosine C chemical structure, C11H17N6O7P, CAS 146425-26-5
Phosmidosine C
CAS 146425-26-5C11H17N6O7P
N-(9-((2R,4S,5R)-4-Hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-8-oxo-8,9-dihydro-7H-purin-6-yl)acetamide chemical structure, C12H15N5O5, CAS 138937-90-3
N-(9-((2R,4S,5R)-4-Hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-8-oxo-8,9-dihydro-7H-purin-6-yl)acetamide
CAS 138937-90-3C12H15N5O5
9-((2R,4S,5R)-4-Hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-6-(methylamino)-7H-purin-8(9H)-one chemical structure, C11H15N5O4, CAS 143740-73-2
9-((2R,4S,5R)-4-Hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-6-(methylamino)-7H-purin-8(9H)-one
CAS 143740-73-2C11H15N5O4
Adenosine 5'-(tetrahydrogen triphosphate), 2'-deoxy-7,8-dihydro-8-oxo- chemical structure, C10H16N5O13P3, CAS 159954-54-8
Adenosine 5'-(tetrahydrogen triphosphate), 2'-deoxy-7,8-dihydro-8-oxo-
CAS 159954-54-8C10H16N5O13P3
6,7-Diamino-9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]purin-8-one chemical structure, C10H14N6O5, CAS 19029-68-6
6,7-Diamino-9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]purin-8-one
CAS 19029-68-6C10H14N6O5
7,8-Dihydro-2'-C-methyl-8-oxo-Adenosine chemical structure, C11H15N5O5, CAS 622380-07-8
7,8-Dihydro-2'-C-methyl-8-oxo-Adenosine
CAS 622380-07-8C11H15N5O5
2-Amino-7-propargyl-7,8-dihydro-8-oxo-9-(beta-D-3-deoxy-ribofuranosyl)purine chemical structure, C13H15N5O4, CAS 2389988-75-2
2-Amino-7-propargyl-7,8-dihydro-8-oxo-9-(beta-D-3-deoxy-ribofuranosyl)purine
CAS 2389988-75-2C13H15N5O4
2-Amino-7-propargyl-7,8-dihydro-8-oxo-9-(beta-D-2,3,5-tri-O-actyl-xylofuranosyl)purine chemical structure, C19H21N5O8, CAS 2389988-52-5
2-Amino-7-propargyl-7,8-dihydro-8-oxo-9-(beta-D-2,3,5-tri-O-actyl-xylofuranosyl)purine
CAS 2389988-52-5C19H21N5O8
2-Amino-9-[(2R,3R,4R,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-7-prop-2-ynylpurin-8-one chemical structure, C13H15N5O5, CAS 2389988-53-6
2-Amino-9-[(2R,3R,4R,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-7-prop-2-ynylpurin-8-one
CAS 2389988-53-6C13H15N5O5
Polvitolimod chemical structure, C13H14FN5O4, CAS 2389988-81-0
Polvitolimod
CAS 2389988-81-0C13H14FN5O4
[(2S,4R,5R)-4-Acetyloxy-5-(2-amino-8-oxo-7H-purin-9-yl)oxolan-2-yl]methyl acetate chemical structure, C14H17N5O6, CAS 2389988-74-1
[(2S,4R,5R)-4-Acetyloxy-5-(2-amino-8-oxo-7H-purin-9-yl)oxolan-2-yl]methyl acetate
CAS 2389988-74-1C14H17N5O6
[(2R,3S,4S,5R)-4-Acetyloxy-5-(2-amino-8-oxo-7-prop-2-ynylpurin-9-yl)-3-fluorooxolan-2-yl]methyl acetate chemical structure, C17H18FN5O6, CAS 2389986-90-5
[(2R,3S,4S,5R)-4-Acetyloxy-5-(2-amino-8-oxo-7-prop-2-ynylpurin-9-yl)-3-fluorooxolan-2-yl]methyl acetate
CAS 2389986-90-5C17H18FN5O6
TLR7agonist13 chemical structure, C17H19N5O6, CAS 2389988-70-7
TLR7agonist13
CAS 2389988-70-7C17H19N5O6
Adenosine,N-acetyl-2',3'-bis-O-[(1,1-dimethylethyl)dimethylsilyl]-7,8-dihydro-8-oxo- chemical structure, C24H43N5O6Si2, CAS 778510-87-5
Adenosine,N-acetyl-2',3'-bis-O-[(1,1-dimethylethyl)dimethylsilyl]-7,8-dihydro-8-oxo-
CAS 778510-87-5C24H43N5O6Si2
Orb3028499 chemical structure, C10H12Li4N5O13P3, CAS 3056945-23-1
Orb3028499
CAS 3056945-23-1C10H12Li4N5O13P3