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Murcko scaffold

Ring system with 4 rings and 19 atoms

5 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
19
Chemicals
5
With full pages
1
Scaffold SMILES

c1ccc(Cn2c3c(c4ccccc42)CCC3)nc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold c1ccc(Cn2c3c(c4ccccc42)CCC3)nc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 5 of 5 chemicals

1-Methylethyl N-((2S)-7-cyano-1,2,3,4-tetrahydro-4-(2-pyridinylmethyl)cyclopent(b)indol-2-yl)carbamate chemical structure, C22H22N4O2, CAS 1029692-15-6
1-Methylethyl N-((2S)-7-cyano-1,2,3,4-tetrahydro-4-(2-pyridinylmethyl)cyclopent(b)indol-2-yl)carbamate
CAS 1029692-15-6C22H22N4O2
Cyclopent(b)indole-7-carbonitrile, 2-amino-1,2,3,4-tetrahydro-4-(2-pyridinylmethyl)-, (2S)- chemical structure, C18H16N4, CAS 1029712-63-7
Cyclopent(b)indole-7-carbonitrile, 2-amino-1,2,3,4-tetrahydro-4-(2-pyridinylmethyl)-, (2S)-
CAS 1029712-63-7C18H16N4
Carbamic acid, N-((2S)-7-cyano-1,2,3,4-tetrahydro-4-(2-pyridinylmethyl)cyclopent(b)indol-2-yl)-, (1R)-2-hydroxy-1-methylethyl ester chemical structure, C22H22N4O3, CAS 1443925-26-5
Carbamic acid, N-((2S)-7-cyano-1,2,3,4-tetrahydro-4-(2-pyridinylmethyl)cyclopent(b)indol-2-yl)-, (1R)-2-hydroxy-1-methylethyl ester
CAS 1443925-26-5C22H22N4O3
Acetamide, N-((2S)-7-cyano-1,2,3,4-tetrahydro-4-(2-pyridinylmethyl)cyclopent(b)indol-2-yl)- chemical structure, C20H18N4O, CAS 1443925-23-2
Acetamide, N-((2S)-7-cyano-1,2,3,4-tetrahydro-4-(2-pyridinylmethyl)cyclopent(b)indol-2-yl)-
CAS 1443925-23-2C20H18N4O
Carbamic acid, N-((2S,3S)-7-cyano-1,2,3,4-tetrahydro-3-hydroxy-4-(2-pyridinylmethyl)cyclopent(b)indol-2-yl)-, 1-methylethyl ester chemical structure, C22H22N4O3, CAS 1443925-24-3
Carbamic acid, N-((2S,3S)-7-cyano-1,2,3,4-tetrahydro-3-hydroxy-4-(2-pyridinylmethyl)cyclopent(b)indol-2-yl)-, 1-methylethyl ester
CAS 1443925-24-3C22H22N4O3