Murcko scaffold
3-Naphthoylindole scaffold
211 chemicals on CompoundList share this ring system.
- Rings
- 4
- Scaffold atoms
- 21
- Chemicals
- 211
- With full pages
- 18
Scaffold SMILES
O=C(c1cccc2ccccc12)c1c[nH]c2ccccc12
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
![Murcko scaffold O=C(c1cccc2ccccc12)c1c[nH]c2ccccc12](/scaffold/QIXQGVQLBPQVOR-UHFFFAOYSA-N/structure.svg)
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 49 to 96 of 211 chemicals
(1-Ethylindol-3-yl)-naphthalen-1-ylmethanone
CAS 209414-05-1C21H17NO
(1-Hexyl-1H-indol-3-yl)-1-naphthalenylmethanone
CAS 209414-08-4C25H25NO
AM 2201
CAS 335161-24-5C24H22FNO
![[2-Methyl-1-(2,2,3,3,4,4,5,5,5-nonadeuteriopentyl)indol-3-yl]-naphthalen-1-ylmethanone chemical structure, C25H25NO, CAS 1651833-48-5](/s/IBBNKINXTRKICJ-ZYWCKPJZSA-N.svg)
[2-Methyl-1-(2,2,3,3,4,4,5,5,5-nonadeuteriopentyl)indol-3-yl]-naphthalen-1-ylmethanone
CAS 1651833-48-5C25H25NO
JWH 073 2-hydroxyindole metabolite
CAS 1427325-54-9C23H21NO2
![Naphthalen-1-yl-[1-(2,2,3,3,4,4,5,5,5-nonadeuteriopentyl)indol-3-yl]methanone chemical structure, C24H23NO, CAS 1415744-44-3](/s/JDNLPKCAXICMBW-WRMMWXQOSA-N.svg)
Naphthalen-1-yl-[1-(2,2,3,3,4,4,5,5,5-nonadeuteriopentyl)indol-3-yl]methanone
CAS 1415744-44-3C24H23NO
JWH 018 2-hydroxyindole metabolite
CAS 1427325-32-3C24H23NO2
JWH 018 4-hydroxyindole metabolite
CAS 1307803-42-4C24H23NO2
JWH 018 5-hydroxyindole metabolite
CAS 1307803-43-5C24H23NO2
JWH 018 6-hydroxyindole metabolite
CAS 1307803-44-6C24H23NO2
JWH 018 7-hydroxyindole metabolite
CAS 1307803-45-7C24H23NO2
5-OH-Jwh-018
CAS 335161-21-2C24H23NO2
JWH-018 N-Pentanoic acid metabolite
CAS 1254475-87-0C24H21NO3
JWH 073 4-hydroxyindole metabolite
CAS 1307803-46-8C23H21NO2
JWH 073 5-hydroxyindole metabolite
CAS 1307803-47-9C23H21NO2
JWH 073 6-hydroxyindole metabolite
CAS 1307803-48-0C23H21NO2
JWH 073 7-hydroxyindole metabolite
CAS 1307803-49-1C23H21NO2
(1-(4-Hydroxybutyl)-1H-indol-3-yl)-1-naphthalenylmethanone
CAS 335161-14-3C23H21NO2
JWH 073 N-butanoic acid metabolite
CAS 1307803-52-6C23H19NO3
JWH 018 N-pentanoic acid metabolite-d4
CAS 1320363-49-2C24H21NO3
JWH-073 (Indole-d5) Butanoic Acid
CAS 1320363-50-5C23H19NO3
JWH 018 N-(3-methylbutyl) isomer
CAS 1346604-93-0C24H23NO
(6-Methoxy-1-pentylindol-3-yl)-naphthalen-1-ylmethanone
CAS 1427325-49-2C25H25NO2
JWH 015-d7
CAS 1346601-16-8C23H21NO
- JWH 018 2-hydroxyindole metabolite-d92749387-82-2C24H23NO2
- JWH 018 4-hydroxyindole metabolite-d92748468-70-2C24H23NO2
- JWH 073-d7 (exempt preparation)1415744-43-2C23H21NO
- JWH 018 N-(2-methylbutyl) isomer1427325-50-5C24H23NO
- JWH 018 5-hydroxyindole metabolite-d92748533-34-6C24H23NO2
- JWH 073 5-hydroxyindole metabolite-d71630022-99-9C23H21NO2
- JWH 073 2-hydroxyindole metabolite-d72748464-25-5C23H21NO2
- JWH 018 6-hydroxyindole metabolite-d92748469-12-5C24H23NO2
- (1-(4-Cyanobutyl)-3-(naphthalen-1-oyl)indole)335161-19-8C24H20N2O
- (1-(5-Fluoropentyl)-3-(naphthalen-1-oyl)-6-nitroindole)335161-27-8C24H21FN2O3
- Jwh-3981292765-18-4C24H22ClNO
- Jwh-4241366068-04-3C24H22BrNO
- (1-(5-Fluoropentyl)-1H-indol-3-yl)(4-methyl-1-naphthalenyl)methanone1354631-24-5C25H24FNO
- JWH 081 4-hydroxynaphthyl metabolite1393345-76-0C24H23NO2
- 1 suppliers3-(Naphthalene-1-carbonyl)-1H-indole-2-carboxylic acid ethyl ester942192-15-6C22H17NO3
- (2-Methyl-1H-indol-3-yl)(4-methylnaphthalen-1-yl)methanone824430-37-7C21H17NO
- (1H-Indol-3-yl)(7-methylnaphthalen-1-yl)methanone824430-40-2C20H15NO
- Jwh 210 3-ethylnaphthyl isomer1547339-60-5C26H27NO
- Jwh-116619294-64-3C26H27NO
- (4-Ethyl-1-naphthalenyl)(1-(5-fluoropentyl)-1H-indol-3-yl)methanone1364933-60-7C26H26FNO
- Naphthalen-1-yl-[1-(1,1,5,5-tetradeuterio-5-fluoropentyl)indol-3-yl]methanone1346605-10-4C24H22FNO
- Naphthalen-1-yl-[1-(1,1,2,2,3,3,4,4,4-nonadeuteriobutyl)indol-3-yl]methanone1346601-94-2C23H21NO
- Naphthalen-1-yl-[1-(1,1,2,2,3,3,4,4,5,5,6,6,6-tridecadeuteriohexyl)indol-3-yl]methanone1346598-25-1C25H25NO
- Methanone, (7-methyl-1-naphthalenyl)(1-pentyl-1H-indol-3-yl)-824960-56-7C25H25NO
Related scaffolds
Same ring framework with different atoms or bond orders
![Scaffold O=c1[nH]c(=O)c2c(ncn2Cc2cccc3ccccc23)[nH]1](/scaffold/DYOXONGUUVOGFO-UHFFFAOYSA-N/structure.svg)
O=c1[nH]c(=O)c2c(ncn2Cc2cccc3ccccc23)[nH]130 chemicals
c1ccc2c(Cn3cnc4ccccc43)cccc2c12 chemicals![Scaffold C=C1CCC2CCCCC2C1Cc1c[nH]c2ccccc12](/scaffold/ZRCTWLKZKAFCJG-UHFFFAOYSA-N/structure.svg)
C=C1CCC2CCCCC2C1Cc1c[nH]c2ccccc122 chemicals![Scaffold O=c1[nH]c(=O)c2c([nH]1)[nH]c(=S)n2Cc1cccc2ccccc12](/scaffold/FANVTHXJRJZNDP-UHFFFAOYSA-N/structure.svg)
O=c1[nH]c(=O)c2c([nH]1)[nH]c(=S)n2Cc1cccc2ccccc121 chemical
O=S(=O)(c1cccc2cccnc12)N1CCc2ccccc211 chemical![Scaffold c1ccc2c(Nc3n[nH]c4ccccc34)ccnc2c1](/scaffold/KIFNPUQVESDJDL-UHFFFAOYSA-N/structure.svg)
c1ccc2c(Nc3n[nH]c4ccccc34)ccnc2c11 chemical
c1ccc2c(Cn3nnc4ccccc43)cccc2c11 chemical
O=C1Nc2ccccc2C1=Cc1cccc2ccccc121 chemical![Scaffold O=S(=O)(c1cccc2ccccc12)c1[nH]nc2ccccc12](/scaffold/NVFIKMXFZUPGJM-UHFFFAOYSA-N/structure.svg)
O=S(=O)(c1cccc2ccccc12)c1[nH]nc2ccccc121 chemical
O=S1(=O)N=C(Oc2cccc3ccccc23)c2ccccc211 chemical![Scaffold c1ccc2c(Cc3n[nH]c4ncncc34)cccc2c1](/scaffold/QTNGCJWHIMFHRT-UHFFFAOYSA-N/structure.svg)
c1ccc2c(Cc3n[nH]c4ncncc34)cccc2c11 chemical
O=C(c1cccc2ccccc12)N1CCc2ccccc211 chemical