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Murcko scaffold

Ring system with 3 rings and 25 atoms

24 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
25
Chemicals
24
With full pages
17
Scaffold SMILES

O=C(COc1ccc(-c2ccccc2)cc1)NN=Cc1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(COc1ccc(-c2ccccc2)cc1)NN=Cc1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 24 of 24 chemicals

2-([1,1'-Biphenyl]-4-yloxy)-N'-(2,3-dichlorobenzylidene)acetohydrazide chemical structure, C21H16Cl2N2O2, CAS 351214-15-8
2-([1,1'-Biphenyl]-4-yloxy)-N'-(2,3-dichlorobenzylidene)acetohydrazide
CAS 351214-15-8C21H16Cl2N2O2
N'-(4-(Allyloxy)benzylidene)-2-((1,1'-biphenyl)-4-yloxy)acetohydrazide chemical structure, C24H22N2O3, CAS 303086-41-1
N'-(4-(Allyloxy)benzylidene)-2-((1,1'-biphenyl)-4-yloxy)acetohydrazide
CAS 303086-41-1C24H22N2O3
N'-Benzylidene-2-((1,1'-biphenyl)-4-yloxy)acetohydrazide chemical structure, C21H18N2O2, CAS 303065-96-5
N'-Benzylidene-2-((1,1'-biphenyl)-4-yloxy)acetohydrazide
CAS 303065-96-5C21H18N2O2
2-((1,1'-Biphenyl)-4-yloxy)-N'-(4-methylbenzylidene)acetohydrazide chemical structure, C22H20N2O2, CAS 303088-39-3
2-((1,1'-Biphenyl)-4-yloxy)-N'-(4-methylbenzylidene)acetohydrazide
CAS 303088-39-3C22H20N2O2
2-((1,1'-Biphenyl)-4-yloxy)-N'-(4-ethoxybenzylidene)acetohydrazide chemical structure, C23H22N2O3, CAS 303088-24-6
2-((1,1'-Biphenyl)-4-yloxy)-N'-(4-ethoxybenzylidene)acetohydrazide
CAS 303088-24-6C23H22N2O3
2-(4-Phenylphenoxy)-N'-[(2,3,4-trimethoxyphenyl)methylidene]acetohydrazide chemical structure, C24H24N2O5, CAS 305850-41-3
2-(4-Phenylphenoxy)-N'-[(2,3,4-trimethoxyphenyl)methylidene]acetohydrazide
CAS 305850-41-3C24H24N2O5
2-((1,1'-Biphenyl)-4-yloxy)-N'-(2-ethoxybenzylidene)propanohydrazide chemical structure, C24H24N2O3, CAS 303087-69-6
2-((1,1'-Biphenyl)-4-yloxy)-N'-(2-ethoxybenzylidene)propanohydrazide
CAS 303087-69-6C24H24N2O3
2-((1,1'-Biphenyl)-4-yloxy)-N'-(2-ethoxybenzylidene)acetohydrazide chemical structure, C23H22N2O3, CAS 303085-17-8
2-((1,1'-Biphenyl)-4-yloxy)-N'-(2-ethoxybenzylidene)acetohydrazide
CAS 303085-17-8C23H22N2O3
2-((1,1'-Biphenyl)-4-yloxy)-N'-(4-methylbenzylidene)propanohydrazide chemical structure, C23H22N2O2, CAS 303085-97-4
2-((1,1'-Biphenyl)-4-yloxy)-N'-(4-methylbenzylidene)propanohydrazide
CAS 303085-97-4C23H22N2O2
2-((1,1'-Biphenyl)-4-yloxy)-N'-(4-chlorobenzylidene)acetohydrazide chemical structure, C21H17ClN2O2, CAS 303086-84-2
2-((1,1'-Biphenyl)-4-yloxy)-N'-(4-chlorobenzylidene)acetohydrazide
CAS 303086-84-2C21H17ClN2O2
2-((1,1'-Biphenyl)-4-yloxy)-N'-(4-methoxybenzylidene)acetohydrazide chemical structure, C22H20N2O3, CAS 303064-43-9
2-((1,1'-Biphenyl)-4-yloxy)-N'-(4-methoxybenzylidene)acetohydrazide
CAS 303064-43-9C22H20N2O3
2-((1,1'-Biphenyl)-4-yloxy)-N'-(3-methoxybenzylidene)acetohydrazide chemical structure, C22H20N2O3, CAS 300676-38-4
2-((1,1'-Biphenyl)-4-yloxy)-N'-(3-methoxybenzylidene)acetohydrazide
CAS 300676-38-4C22H20N2O3
2-((1,1'-Biphenyl)-4-yloxy)-N'-(2-methoxybenzylidene)acetohydrazide chemical structure, C22H20N2O3, CAS 303085-21-4
2-((1,1'-Biphenyl)-4-yloxy)-N'-(2-methoxybenzylidene)acetohydrazide
CAS 303085-21-4C22H20N2O3
2-((1,1'-Biphenyl)-4-yloxy)-N'-(4-butoxybenzylidene)propanohydrazide chemical structure, C26H28N2O3, CAS 303088-13-3
2-((1,1'-Biphenyl)-4-yloxy)-N'-(4-butoxybenzylidene)propanohydrazide
CAS 303088-13-3C26H28N2O3
2-(Biphenyl-4-yloxy)-N'-[(Z)-(2-hydroxy-3-methylphenyl)methylidene]acetohydrazide chemical structure, C22H20N2O3, CAS 6101-91-3
2-(Biphenyl-4-yloxy)-N'-[(Z)-(2-hydroxy-3-methylphenyl)methylidene]acetohydrazide
CAS 6101-91-3C22H20N2O3
2-([1,1'-Biphenyl]-4-yloxy)-N'-{3-ethoxy-4-hydroxy-5-nitrobenzylidene}acetohydrazide chemical structure, C23H21N3O6, CAS 491598-26-6
2-([1,1'-Biphenyl]-4-yloxy)-N'-{3-ethoxy-4-hydroxy-5-nitrobenzylidene}acetohydrazide
CAS 491598-26-6C23H21N3O6
2-(Biphenyl-4-yloxy)-N'-[(E)-(2-hydroxy-3-methoxyphenyl)methylidene]acetohydrazide chemical structure, C22H20N2O4, CAS 303085-55-4
2-(Biphenyl-4-yloxy)-N'-[(E)-(2-hydroxy-3-methoxyphenyl)methylidene]acetohydrazide
CAS 303085-55-4C22H20N2O4
2-(Biphenyl-4-yloxy)-N'-[(E)-(3-ethoxy-4-hydroxyphenyl)methylidene]acetohydrazide chemical structure, C23H22N2O4, CAS 651707-41-4
2-(Biphenyl-4-yloxy)-N'-[(E)-(3-ethoxy-4-hydroxyphenyl)methylidene]acetohydrazide
CAS 651707-41-4C23H22N2O4
2-((1,1'-Biphenyl)-4-yloxy)-N'-(2,4-dihydroxybenzylidene)propanohydrazide chemical structure, C22H20N2O4, CAS 303088-36-0
2-((1,1'-Biphenyl)-4-yloxy)-N'-(2,4-dihydroxybenzylidene)propanohydrazide
CAS 303088-36-0C22H20N2O4
2-((1,1'-Biphenyl)-4-yloxy)-N'-(2-hydroxy-3-methoxybenzylidene)propanohydrazide chemical structure, C23H22N2O4, CAS 303086-36-4
2-((1,1'-Biphenyl)-4-yloxy)-N'-(2-hydroxy-3-methoxybenzylidene)propanohydrazide
CAS 303086-36-4C23H22N2O4
2-((1,1'-Biphenyl)-4-yloxy)-N'-(2-hydroxybenzylidene)acetohydrazide chemical structure, C21H18N2O3, CAS 303087-01-6
2-((1,1'-Biphenyl)-4-yloxy)-N'-(2-hydroxybenzylidene)acetohydrazide
CAS 303087-01-6C21H18N2O3
2-((1,1'-Biphenyl)-4-yloxy)-N'-(5-bromo-2-hydroxybenzylidene)acetohydrazide chemical structure, C21H17BrN2O3, CAS 300771-36-2
2-((1,1'-Biphenyl)-4-yloxy)-N'-(5-bromo-2-hydroxybenzylidene)acetohydrazide
CAS 300771-36-2C21H17BrN2O3
2-((1,1'-Biphenyl)-4-yloxy)-N'-(4-hydroxybenzylidene)propanohydrazide chemical structure, C22H20N2O3, CAS 303086-13-7
2-((1,1'-Biphenyl)-4-yloxy)-N'-(4-hydroxybenzylidene)propanohydrazide
CAS 303086-13-7C22H20N2O3
2-([1,1'-Biphenyl]-4-yloxy)-N'-(2,3-dibromo-5-ethoxy-4-hydroxybenzylidene)acetohydrazide chemical structure, C23H20Br2N2O4, CAS 867370-40-9
2-([1,1'-Biphenyl]-4-yloxy)-N'-(2,3-dibromo-5-ethoxy-4-hydroxybenzylidene)acetohydrazide
CAS 867370-40-9C23H20Br2N2O4