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Murcko scaffold

Ring system with 3 rings and 26 atoms

6 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
26
Chemicals
6
With full pages
1
Scaffold SMILES

O=C(COc1ccccc1)NC(=S)Nc1ccc(N2CCOCC2)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(COc1ccccc1)NC(=S)Nc1ccc(N2CCOCC2)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 6 of 6 chemicals

2-(3,4-Dimethylphenoxy)-N-[(4-morpholin-4-ylphenyl)carbamothioyl]acetamide chemical structure, C21H25N3O3S, CAS 445411-68-7
2-(3,4-Dimethylphenoxy)-N-[(4-morpholin-4-ylphenyl)carbamothioyl]acetamide
CAS 445411-68-7C21H25N3O3S
N-{[3-Chloro-4-(morpholin-4-yl)phenyl]carbamothioyl}-2-phenoxyacetamide chemical structure, C19H20ClN3O3S, CAS 443291-04-1
N-{[3-Chloro-4-(morpholin-4-yl)phenyl]carbamothioyl}-2-phenoxyacetamide
CAS 443291-04-1C19H20ClN3O3S
2-(4-Bromophenoxy)-N-{[3-chloro-4-(morpholin-4-yl)phenyl]carbamothioyl}acetamide chemical structure, C19H19BrClN3O3S, CAS 371925-40-5
2-(4-Bromophenoxy)-N-{[3-chloro-4-(morpholin-4-yl)phenyl]carbamothioyl}acetamide
CAS 371925-40-5C19H19BrClN3O3S
2-(4-Methylphenoxy)-N-[(4-morpholin-4-ylphenyl)carbamothioyl]acetamide chemical structure, C20H23N3O3S, CAS 425662-77-7
2-(4-Methylphenoxy)-N-[(4-morpholin-4-ylphenyl)carbamothioyl]acetamide
CAS 425662-77-7C20H23N3O3S
N-[(3-Chloro-4-morpholin-4-ylphenyl)carbamothioyl]-2-(4-methylphenoxy)acetamide chemical structure, C20H22ClN3O3S, CAS 426242-67-3
N-[(3-Chloro-4-morpholin-4-ylphenyl)carbamothioyl]-2-(4-methylphenoxy)acetamide
CAS 426242-67-3C20H22ClN3O3S
N-[(3-Chloro-4-morpholin-4-ylphenyl)carbamothioyl]-2-(2-methylphenoxy)acetamide chemical structure, C20H22ClN3O3S, CAS 432502-43-7
N-[(3-Chloro-4-morpholin-4-ylphenyl)carbamothioyl]-2-(2-methylphenoxy)acetamide
CAS 432502-43-7C20H22ClN3O3S