CompoundList
Sign in
Murcko scaffold

Ring system with 3 rings and 27 atoms

32 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
27
Chemicals
32
With full pages
9
Scaffold SMILES

O=C(Cc1ccccc1)NCCS(=O)(=O)N1CCN(c2ccccc2)CC1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(Cc1ccccc1)NCCS(=O)(=O)N1CCN(c2ccccc2)CC1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 32 of 32 chemicals

2-(4-Fluorophenyl)-N-[2-(4-phenylpiperazin-1-yl)sulfonylethyl]acetamide chemical structure, C20H24FN3O3S, CAS 897621-73-7
2-(4-Fluorophenyl)-N-[2-(4-phenylpiperazin-1-yl)sulfonylethyl]acetamide
CAS 897621-73-7C20H24FN3O3S
2-(4-Chlorophenyl)-N-[2-(4-phenylpiperazin-1-yl)sulfonylethyl]acetamide chemical structure, C20H24ClN3O3S, CAS 897621-75-9
2-(4-Chlorophenyl)-N-[2-(4-phenylpiperazin-1-yl)sulfonylethyl]acetamide
CAS 897621-75-9C20H24ClN3O3S
N-(2-((4-Phenylpiperazin-1-yl)sulfonyl)ethyl)-2-(m-tolyl)acetamide chemical structure, C21H27N3O3S, CAS 897621-79-3
N-(2-((4-Phenylpiperazin-1-yl)sulfonyl)ethyl)-2-(m-tolyl)acetamide
CAS 897621-79-3C21H27N3O3S
2-(3,4-Dimethoxyphenyl)-N-(2-{[4-(4-fluorophenyl)piperazin-1-yl]sulfonyl}ethyl)acetamide chemical structure, C22H28FN3O5S, CAS 933217-23-3
2-(3,4-Dimethoxyphenyl)-N-(2-{[4-(4-fluorophenyl)piperazin-1-yl]sulfonyl}ethyl)acetamide
CAS 933217-23-3C22H28FN3O5S
2-(3,4-Dimethoxyphenyl)-N-(2-{[4-(4-methoxyphenyl)piperazin-1-yl]sulfonyl}ethyl)acetamide chemical structure, C23H31N3O6S, CAS 933027-56-6
2-(3,4-Dimethoxyphenyl)-N-(2-{[4-(4-methoxyphenyl)piperazin-1-yl]sulfonyl}ethyl)acetamide
CAS 933027-56-6C23H31N3O6S
2-(4-Chlorophenyl)-N-(2-{[4-(4-methoxyphenyl)piperazin-1-yl]sulfonyl}ethyl)acetamide chemical structure, C21H26ClN3O4S, CAS 904830-23-5
2-(4-Chlorophenyl)-N-(2-{[4-(4-methoxyphenyl)piperazin-1-yl]sulfonyl}ethyl)acetamide
CAS 904830-23-5C21H26ClN3O4S
N-(2-((4-(3-Chlorophenyl)piperazin-1-yl)sulfonyl)ethyl)-2-phenylacetamide chemical structure, C20H24ClN3O3S, CAS 897613-12-6
N-(2-((4-(3-Chlorophenyl)piperazin-1-yl)sulfonyl)ethyl)-2-phenylacetamide
CAS 897613-12-6C20H24ClN3O3S
N-(2-{[4-(3-Chlorophenyl)piperazin-1-yl]sulfonyl}ethyl)-2-(4-fluorophenyl)acetamide chemical structure, C20H23ClFN3O3S, CAS 897613-15-9
N-(2-{[4-(3-Chlorophenyl)piperazin-1-yl]sulfonyl}ethyl)-2-(4-fluorophenyl)acetamide
CAS 897613-15-9C20H23ClFN3O3S
2-(4-Chlorophenyl)-N-(2-{[4-(2-fluorophenyl)piperazin-1-yl]sulfonyl}ethyl)acetamide chemical structure, C20H23ClFN3O3S, CAS 897618-29-0
2-(4-Chlorophenyl)-N-(2-{[4-(2-fluorophenyl)piperazin-1-yl]sulfonyl}ethyl)acetamide
CAS 897618-29-0C20H23ClFN3O3S
N-(2-((4-(4-Fluorophenyl)piperazin-1-yl)sulfonyl)ethyl)-2-phenylacetamide chemical structure, C20H24FN3O3S, CAS 897618-88-1
N-(2-((4-(4-Fluorophenyl)piperazin-1-yl)sulfonyl)ethyl)-2-phenylacetamide
CAS 897618-88-1C20H24FN3O3S
2-(4-Fluorophenyl)-N-(2-((4-(4-fluorophenyl)piperazin-1-yl)sulfonyl)ethyl)acetamide chemical structure, C20H23F2N3O3S, CAS 897618-91-6
2-(4-Fluorophenyl)-N-(2-((4-(4-fluorophenyl)piperazin-1-yl)sulfonyl)ethyl)acetamide
CAS 897618-91-6C20H23F2N3O3S
2-(4-Chlorophenyl)-N-(2-{[4-(4-fluorophenyl)piperazin-1-yl]sulfonyl}ethyl)acetamide chemical structure, C20H23ClFN3O3S, CAS 897618-92-7
2-(4-Chlorophenyl)-N-(2-{[4-(4-fluorophenyl)piperazin-1-yl]sulfonyl}ethyl)acetamide
CAS 897618-92-7C20H23ClFN3O3S
2-(4-Methoxyphenyl)-N-(2-{[4-(2-methoxyphenyl)piperazin-1-yl]sulfonyl}ethyl)acetamide chemical structure, C22H29N3O5S, CAS 897611-38-0
2-(4-Methoxyphenyl)-N-(2-{[4-(2-methoxyphenyl)piperazin-1-yl]sulfonyl}ethyl)acetamide
CAS 897611-38-0C22H29N3O5S
2-(3,4-Dimethoxyphenyl)-N-(2-((4-phenylpiperazin-1-yl)sulfonyl)ethyl)acetamide chemical structure, C22H29N3O5S, CAS 897621-69-1
2-(3,4-Dimethoxyphenyl)-N-(2-((4-phenylpiperazin-1-yl)sulfonyl)ethyl)acetamide
CAS 897621-69-1C22H29N3O5S
N-(2-((4-(2-Fluorophenyl)piperazin-1-yl)sulfonyl)ethyl)-2-(4-methoxyphenyl)acetamide chemical structure, C21H26FN3O4S, CAS 897618-26-7
N-(2-((4-(2-Fluorophenyl)piperazin-1-yl)sulfonyl)ethyl)-2-(4-methoxyphenyl)acetamide
CAS 897618-26-7C21H26FN3O4S
2-(4-Ethoxyphenyl)-N-(2-{[4-(2-fluorophenyl)piperazin-1-yl]sulfonyl}ethyl)acetamide chemical structure, C22H28FN3O4S, CAS 897618-27-8
2-(4-Ethoxyphenyl)-N-(2-{[4-(2-fluorophenyl)piperazin-1-yl]sulfonyl}ethyl)acetamide
CAS 897618-27-8C22H28FN3O4S
N-(2-((4-(4-Fluorophenyl)piperazin-1-yl)sulfonyl)ethyl)-2-(4-methoxyphenyl)acetamide chemical structure, C21H26FN3O4S, CAS 897618-89-2
N-(2-((4-(4-Fluorophenyl)piperazin-1-yl)sulfonyl)ethyl)-2-(4-methoxyphenyl)acetamide
CAS 897618-89-2C21H26FN3O4S
N-(2-((4-(4-Methoxyphenyl)piperazin-1-yl)sulfonyl)ethyl)-2-phenylacetamide chemical structure, C21H27N3O4S, CAS 897610-80-9
N-(2-((4-(4-Methoxyphenyl)piperazin-1-yl)sulfonyl)ethyl)-2-phenylacetamide
CAS 897610-80-9C21H27N3O4S
2-(4-Fluorophenyl)-N-(2-{[4-(4-methoxyphenyl)piperazin-1-yl]sulfonyl}ethyl)acetamide chemical structure, C21H26FN3O4S, CAS 897610-82-1
2-(4-Fluorophenyl)-N-(2-{[4-(4-methoxyphenyl)piperazin-1-yl]sulfonyl}ethyl)acetamide
CAS 897610-82-1C21H26FN3O4S
N-(2-((4-(4-Methoxyphenyl)piperazin-1-yl)sulfonyl)ethyl)-2-(m-tolyl)acetamide chemical structure, C22H29N3O4S, CAS 897610-83-2
N-(2-((4-(4-Methoxyphenyl)piperazin-1-yl)sulfonyl)ethyl)-2-(m-tolyl)acetamide
CAS 897610-83-2C22H29N3O4S
2-(4-Fluorophenyl)-N-(2-((4-(2-methoxyphenyl)piperazin-1-yl)sulfonyl)ethyl)acetamide chemical structure, C21H26FN3O4S, CAS 897611-40-4
2-(4-Fluorophenyl)-N-(2-((4-(2-methoxyphenyl)piperazin-1-yl)sulfonyl)ethyl)acetamide
CAS 897611-40-4C21H26FN3O4S
2-(4-Fluorophenyl)-N-(2-((4-(2-fluorophenyl)piperazin-1-yl)sulfonyl)ethyl)acetamide chemical structure, C20H23F2N3O3S, CAS 897618-28-9
2-(4-Fluorophenyl)-N-(2-((4-(2-fluorophenyl)piperazin-1-yl)sulfonyl)ethyl)acetamide
CAS 897618-28-9C20H23F2N3O3S
2-(4-Ethoxyphenyl)-N-(2-{[4-(4-fluorophenyl)piperazin-1-yl]sulfonyl}ethyl)acetamide chemical structure, C22H28FN3O4S, CAS 897618-90-5
2-(4-Ethoxyphenyl)-N-(2-{[4-(4-fluorophenyl)piperazin-1-yl]sulfonyl}ethyl)acetamide
CAS 897618-90-5C22H28FN3O4S
N-(2-((4-(4-Fluorophenyl)piperazin-1-yl)sulfonyl)ethyl)-2-(m-tolyl)acetamide chemical structure, C21H26FN3O3S, CAS 897618-93-8
N-(2-((4-(4-Fluorophenyl)piperazin-1-yl)sulfonyl)ethyl)-2-(m-tolyl)acetamide
CAS 897618-93-8C21H26FN3O3S