CompoundList
Sign in
Murcko scaffold

Ring system with 4 rings and 21 atoms

9 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
21
Chemicals
9
With full pages
1
Scaffold SMILES

O=C(c1ccccc1)c1cc2cc3c(nc2s1)CCCC3

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(c1ccccc1)c1cc2cc3c(nc2s1)CCCC3

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 9 of 9 chemicals

2-[(4-Chlorophenyl)carbonyl]-5H,6H,7H,8H-thieno[2,3-b]quinolin-3-amine chemical structure, C18H15ClN2OS, CAS 296797-33-6
2-[(4-Chlorophenyl)carbonyl]-5H,6H,7H,8H-thieno[2,3-b]quinolin-3-amine
CAS 296797-33-6C18H15ClN2OS
(3-Amino-5,6,7,8-tetrahydrothieno(2,3-B)quinolin-2-yl)(phenyl)methanone chemical structure, C18H16N2OS, CAS 326918-81-4
(3-Amino-5,6,7,8-tetrahydrothieno(2,3-B)quinolin-2-yl)(phenyl)methanone
CAS 326918-81-4C18H16N2OS
(3-Amino-5,6,7,8-tetrahydrothieno[2,3-b]quinolin-2-yl)(4-methylphenyl)methanone chemical structure, C19H18N2OS, CAS 330181-46-9
(3-Amino-5,6,7,8-tetrahydrothieno[2,3-b]quinolin-2-yl)(4-methylphenyl)methanone
CAS 330181-46-9C19H18N2OS
(3-Amino-6-ethyl-5,6,7,8-tetrahydrothieno[2,3-b]quinolin-2-yl)(3-methoxyphenyl)methanone chemical structure, C21H22N2O2S, CAS 445269-24-9
(3-Amino-6-ethyl-5,6,7,8-tetrahydrothieno[2,3-b]quinolin-2-yl)(3-methoxyphenyl)methanone
CAS 445269-24-9C21H22N2O2S
(3-Amino-6-ethyl-5,6,7,8-tetrahydrothieno[2,3-b]quinolin-2-yl)(4-bromophenyl)methanone chemical structure, C20H19BrN2OS, CAS 445269-21-6
(3-Amino-6-ethyl-5,6,7,8-tetrahydrothieno[2,3-b]quinolin-2-yl)(4-bromophenyl)methanone
CAS 445269-21-6C20H19BrN2OS
(3-Amino-6-ethyl-5,6,7,8-tetrahydrothieno[2,3-b]quinolin-2-yl)(4-fluorophenyl)methanone chemical structure, C20H19FN2OS, CAS 445269-22-7
(3-Amino-6-ethyl-5,6,7,8-tetrahydrothieno[2,3-b]quinolin-2-yl)(4-fluorophenyl)methanone
CAS 445269-22-7C20H19FN2OS
(3-Amino-6-ethyl-5,6,7,8-tetrahydrothieno[2,3-b]quinolin-2-yl)(3,4-dimethoxyphenyl)methanone chemical structure, C22H24N2O3S, CAS 445269-20-5
(3-Amino-6-ethyl-5,6,7,8-tetrahydrothieno[2,3-b]quinolin-2-yl)(3,4-dimethoxyphenyl)methanone
CAS 445269-20-5C22H24N2O3S
(3-Amino-6-ethyl-5,6,7,8-tetrahydrothieno[2,3-b]quinolin-2-yl)(2,5-dimethoxyphenyl)methanone chemical structure, C22H24N2O3S, CAS 664994-11-0
(3-Amino-6-ethyl-5,6,7,8-tetrahydrothieno[2,3-b]quinolin-2-yl)(2,5-dimethoxyphenyl)methanone
CAS 664994-11-0C22H24N2O3S
(3-Amino-6-ethyl-5,6,7,8-tetrahydrothieno[2,3-b]quinolin-2-yl)(4-methylphenyl)methanone chemical structure, C21H22N2OS, CAS 445269-23-8
(3-Amino-6-ethyl-5,6,7,8-tetrahydrothieno[2,3-b]quinolin-2-yl)(4-methylphenyl)methanone
CAS 445269-23-8C21H22N2OS