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Murcko scaffold

Ring system with 4 rings and 19 atoms

12 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
19
Chemicals
12
With full pages
3
Scaffold SMILES

C1=CC(c2ccccc2)c2cc3c(cc2O1)OCO3

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold C1=CC(c2ccccc2)c2cc3c(cc2O1)OCO3

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 12 of 12 chemicals

6,7-Dimethyl-8-(3,4,5-trimethoxyphenyl)-8H-[1,3]dioxolo[4,5-g]chromene chemical structure, C21H22O6, CAS 116409-24-6
6,7-Dimethyl-8-(3,4,5-trimethoxyphenyl)-8H-[1,3]dioxolo[4,5-g]chromene
CAS 116409-24-6C21H22O6
7-Methyl-8-(3,4,5-trimethoxyphenyl)-8H-1,3-dioxolo(4,5-g)(1)benzopyran chemical structure, C20H20O6, CAS 117211-87-7
7-Methyl-8-(3,4,5-trimethoxyphenyl)-8H-1,3-dioxolo(4,5-g)(1)benzopyran
CAS 117211-87-7C20H20O6
1-(6-Methyl-8-(3,4,5-trimethoxyphenyl)-8H-1,3-dioxolo(4,5-g)(1)benzopyran-7-yl)ethanone chemical structure, C22H22O7, CAS 117233-19-9
1-(6-Methyl-8-(3,4,5-trimethoxyphenyl)-8H-1,3-dioxolo(4,5-g)(1)benzopyran-7-yl)ethanone
CAS 117233-19-9C22H22O7
6-Amino-8-(5-bromo-2-prop-2-enoxyphenyl)-8H-[1,3]dioxolo[4,5-g]chromene-7-carbonitrile chemical structure, C20H15BrN2O4, CAS 663214-75-3
6-Amino-8-(5-bromo-2-prop-2-enoxyphenyl)-8H-[1,3]dioxolo[4,5-g]chromene-7-carbonitrile
CAS 663214-75-3C20H15BrN2O4
6-Amino-8-(3-bromo-5-ethoxy-4-prop-2-enoxyphenyl)-8H-[1,3]dioxolo[4,5-g]chromene-7-carbonitrile chemical structure, C22H19BrN2O5, CAS 663159-00-0
6-Amino-8-(3-bromo-5-ethoxy-4-prop-2-enoxyphenyl)-8H-[1,3]dioxolo[4,5-g]chromene-7-carbonitrile
CAS 663159-00-0C22H19BrN2O5
6-Amino-8-(3-bromo-4-ethoxy-5-methoxyphenyl)-8H-[1,3]dioxolo[4,5-g]chromene-7-carbonitrile chemical structure, C20H17BrN2O5, CAS 663214-01-5
6-Amino-8-(3-bromo-4-ethoxy-5-methoxyphenyl)-8H-[1,3]dioxolo[4,5-g]chromene-7-carbonitrile
CAS 663214-01-5C20H17BrN2O5
Methyl 4-(6-amino-7-cyano-8H-[1,3]dioxolo[4,5-g]chromen-8-yl)benzoate chemical structure, C19H14N2O5, CAS 663214-03-7
Methyl 4-(6-amino-7-cyano-8H-[1,3]dioxolo[4,5-g]chromen-8-yl)benzoate
CAS 663214-03-7C19H14N2O5
6-Amino-8-(4-chlorophenyl)-8H-[1,3]dioxolo[4,5-g]chromene-7-carbonitrile chemical structure, C17H11ClN2O3, CAS 663159-07-7
6-Amino-8-(4-chlorophenyl)-8H-[1,3]dioxolo[4,5-g]chromene-7-carbonitrile
CAS 663159-07-7C17H11ClN2O3
6-Amino-8-(2-bromo-5-ethoxy-4-methoxyphenyl)-8H-[1,3]dioxolo[4,5-g]chromene-7-carbonitrile chemical structure, C20H17BrN2O5, CAS 663207-37-2
6-Amino-8-(2-bromo-5-ethoxy-4-methoxyphenyl)-8H-[1,3]dioxolo[4,5-g]chromene-7-carbonitrile
CAS 663207-37-2C20H17BrN2O5
6-Amino-8-(3,4,5-trimethoxyphenyl)-8H-[1,3]dioxolo[4,5-g]chromene-7-carbonitrile chemical structure, C20H18N2O6, CAS 663214-48-0
6-Amino-8-(3,4,5-trimethoxyphenyl)-8H-[1,3]dioxolo[4,5-g]chromene-7-carbonitrile
CAS 663214-48-0C20H18N2O6
8-(4-(Allyloxy)-3-bromo-5-methoxyphenyl)-6-amino-8H-[1,3]dioxolo[4,5-g]chromene-7-carbonitrile chemical structure, C21H17BrN2O5, CAS 663213-98-7
8-(4-(Allyloxy)-3-bromo-5-methoxyphenyl)-6-amino-8H-[1,3]dioxolo[4,5-g]chromene-7-carbonitrile
CAS 663213-98-7C21H17BrN2O5
6-Amino-8-(3-bromo-4,5-dimethoxyphenyl)-8H-[1,3]dioxolo[4,5-g]chromene-7-carbonitrile chemical structure, C19H15BrN2O5, CAS 663214-57-1
6-Amino-8-(3-bromo-4,5-dimethoxyphenyl)-8H-[1,3]dioxolo[4,5-g]chromene-7-carbonitrile
CAS 663214-57-1C19H15BrN2O5