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Murcko scaffold

Ring system with 4 rings and 19 atoms

18 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
19
Chemicals
18
With full pages
4
Scaffold SMILES

c1ccc(C2CCCc3cc4c(cc32)OCO4)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold c1ccc(C2CCCc3cc4c(cc32)OCO4)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 18 of 18 chemicals

Podophyllic acid chemical structure, C22H24O9, CAS 1853-37-8
Podophyllic acid
CAS 1853-37-8C22H24O9
Nirtetralin chemical structure, C24H30O7, CAS 50656-78-5
Nirtetralin
CAS 50656-78-5C24H30O7
Mitopodozide chemical structure, C24H30N2O8, CAS 1508-45-8
Mitopodozide
CAS 1508-45-8C24H30N2O8
8-Hydroxy-7-(hydroxymethyl)-5-(3,4,5-trimethoxyphenyl)-5,6,7,8-tetrahydro-2H-naphtho[2,3-d][1,3]dioxole-6-carboxylic acid chemical structure, C22H24O9, CAS 4354-75-0
8-Hydroxy-7-(hydroxymethyl)-5-(3,4,5-trimethoxyphenyl)-5,6,7,8-tetrahydro-2H-naphtho[2,3-d][1,3]dioxole-6-carboxylic acid
CAS 4354-75-0C22H24O9
Picropodophyllic acid chemical structure, C22H24O9, CAS 477-67-8
Picropodophyllic acid
CAS 477-67-8C22H24O9
Podophyllum (resin) chemical structure, C88H92O34, CAS 9000-55-9
Podophyllum (resin)
CAS 9000-55-9C88H92O34
(5R,6R,7R,8S)-8-Hydroxy-7-(hydroxymethyl)-5-(3,4,5-trimethoxyphenyl)-5,6,7,8-tetrahydrobenzo[f][1,3]benzodioxole-6-carboxylic acid chemical structure, C22H24O9, CAS 113565-15-4
(5R,6R,7R,8S)-8-Hydroxy-7-(hydroxymethyl)-5-(3,4,5-trimethoxyphenyl)-5,6,7,8-tetrahydrobenzo[f][1,3]benzodioxole-6-carboxylic acid
CAS 113565-15-4C22H24O9
(-)-Nirtetralin chemical structure, C24H30O7, CAS 78185-63-4
(-)-Nirtetralin
CAS 78185-63-4C24H30O7
Podophyllinic acid hydrazide chemical structure, C22H26N2O8, CAS 78178-41-3
Podophyllinic acid hydrazide
CAS 78178-41-3C22H26N2O8
Podophyllic acid sodium salt chemical structure, C22H23NaO9, CAS 6278-06-4
Podophyllic acid sodium salt
CAS 6278-06-4C22H23NaO9
Phenol, 2-methoxy-4-[(5R,6R,7S)-5,6,7,8-tetrahydro-6,7-dimethylnaphtho[2,3-d]-1,3-dioxol-5-yl]-, rel- chemical structure, C20H22O4, CAS 80483-35-8
Phenol, 2-methoxy-4-[(5R,6R,7S)-5,6,7,8-tetrahydro-6,7-dimethylnaphtho[2,3-d]-1,3-dioxol-5-yl]-, rel-
CAS 80483-35-8C20H22O4
Podophyllic acid sodium salt chemical structure, C22H24NaO9+
Podophyllic acid sodium salt
C22H24NaO9+
Isolintetralin chemical structure, C23H28O6, CAS 145459-30-9
Isolintetralin
CAS 145459-30-9C23H28O6
Podophyllol chemical structure, C22H26O8, CAS 78339-51-2
Podophyllol
CAS 78339-51-2C22H26O8
Picropodophyllol chemical structure, C22H26O8, CAS 3811-15-2
Picropodophyllol
CAS 3811-15-2C22H26O8
(5R,6R,7R)-5-(3,4-Dimethoxyphenyl)-6,7-bis(methoxymethyl)-5,6,7,8-tetrahydrobenzo[f][1,3]benzodioxole chemical structure, C23H28O6
(5R,6R,7R)-5-(3,4-Dimethoxyphenyl)-6,7-bis(methoxymethyl)-5,6,7,8-tetrahydrobenzo[f][1,3]benzodioxole
C23H28O6
5-(3,4-Dimethoxyphenyl)-6,7-bis(methoxymethyl)-5,6,7,8-tetrahydrobenzo[f][1,3]benzodioxole chemical structure, C23H28O6
5-(3,4-Dimethoxyphenyl)-6,7-bis(methoxymethyl)-5,6,7,8-tetrahydrobenzo[f][1,3]benzodioxole
C23H28O6
(6R,7R)-5-(3,4-Dimethoxyphenyl)-6,7-bis(methoxymethyl)-5,6,7,8-tetrahydrobenzo[f][1,3]benzodioxole chemical structure, C23H28O6
(6R,7R)-5-(3,4-Dimethoxyphenyl)-6,7-bis(methoxymethyl)-5,6,7,8-tetrahydrobenzo[f][1,3]benzodioxole
C23H28O6