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Murcko scaffold

2,3,5-Triphenyldihydro-2H-pyrrolo[3,4-d][1,2]oxazole-4,6(3H,5H)-dione scaffold

213 chemicals on CompoundList share this ring system.

Rings: 5
Scaffold atoms: 28
Chemicals: 213
With full pages: 11

Scaffold SMILES

O=C1C2ON(c3ccccc3)C(c3ccccc3)C2C(=O)N1c1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold Open the 2,3,5-Triphenyldihydro-2H-pyrrolo[3,4-d][1,2]oxazole-4,6(3H,5H)-dione page

Murcko scaffold O=C1C2ON(c3ccccc3)C(c3ccccc3)C2C(=O)N1c1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 213 chemicals

2,3,5-Triphenyldihydro-2H-pyrrolo[3,4-d][1,2]oxazole-4,6(3H,5H)-dione chemical structure, C23H18N2O3, CAS 21939-12-8

2,3,5-Triphenyldihydro-2H-pyrrolo[3,4-d][1,2]oxazole-4,6(3H,5H)-dione

CAS 21939-12-8C₂₃H₁₈N₂O₃

{2-[5-(4-Fluorophenyl)-4,6-dioxo-2-phenylhexahydro-2H-pyrrolo[3,4-d][1,2]oxazol-3-yl]phenoxy}acetic acid chemical structure, C25H19FN2O6, CAS 1005082-82-5

{2-[5-(4-Fluorophenyl)-4,6-dioxo-2-phenylhexahydro-2H-pyrrolo[3,4-d][1,2]oxazol-3-yl]phenoxy}acetic acid

CAS 1005082-82-5C₂₅H₁₉FN₂O₆

3-(4-(Dimethylamino)phenyl)-5-phenyl-2-(o-tolyl)dihydro-2H-pyrrolo[3,4-d]isoxazole-4,6(5H,6aH)-dione chemical structure, C26H25N3O3, CAS 312605-65-5

3-(4-(Dimethylamino)phenyl)-5-phenyl-2-(o-tolyl)dihydro-2H-pyrrolo[3,4-d]isoxazole-4,6(5H,6aH)-dione

CAS 312605-65-5C₂₆H₂₅N₃O₃

3-(4-Fluorophenyl)-2,5-diphenyldihydro-2H-pyrrolo[3,4-d]isoxazole-4,6(5H,6aH)-dione chemical structure, C23H17FN2O3, CAS 331632-66-7

3-(4-Fluorophenyl)-2,5-diphenyldihydro-2H-pyrrolo[3,4-d]isoxazole-4,6(5H,6aH)-dione

CAS 331632-66-7C₂₃H₁₇FN₂O₃

3-(4-Methoxyphenyl)-2,5-diphenyldihydro-2H-pyrrolo[3,4-d]isoxazole-4,6(5H,6aH)-dione chemical structure, C24H20N2O4, CAS 68295-59-0

3-(4-Methoxyphenyl)-2,5-diphenyldihydro-2H-pyrrolo[3,4-d]isoxazole-4,6(5H,6aH)-dione

CAS 68295-59-0C₂₄H₂₀N₂O₄

5-(2-Chlorophenyl)-3-(4-(dimethylamino)phenyl)-2-phenyldihydro-2H-pyrrolo(3,4-D)isoxazole-4,6(3H,5H)-dione chemical structure, C25H22ClN3O3, CAS 308101-49-7

5-(2-Chlorophenyl)-3-(4-(dimethylamino)phenyl)-2-phenyldihydro-2H-pyrrolo(3,4-D)isoxazole-4,6(3H,5H)-dione

CAS 308101-49-7C₂₅H₂₂ClN₃O₃

2-(4-Chlorophenyl)-3-(4-hydroxyphenyl)-5-(2-methoxyphenyl)dihydro-2H-pyrrolo[3,4-d]isoxazole-4,6(5H,6aH)-dione chemical structure, C24H19ClN2O5, CAS 256332-72-6

2-(4-Chlorophenyl)-3-(4-hydroxyphenyl)-5-(2-methoxyphenyl)dihydro-2H-pyrrolo[3,4-d]isoxazole-4,6(5H,6aH)-dione

CAS 256332-72-6C₂₄H₁₉ClN₂O₅

3-(5-Bromo-2-hydroxyphenyl)-5-(2-chlorophenyl)-2-phenyldihydro-2H-pyrrolo[3,4-d]isoxazole-4,6(3H,5H)-dione chemical structure, C23H16BrClN2O4, CAS 353793-08-5

3-(5-Bromo-2-hydroxyphenyl)-5-(2-chlorophenyl)-2-phenyldihydro-2H-pyrrolo[3,4-d]isoxazole-4,6(3H,5H)-dione

CAS 353793-08-5C₂₃H₁₆BrClN₂O₄

3-(4-Fluorophenyl)-2-phenyl-5-(p-tolyl)dihydro-2H-pyrrolo[3,4-d]isoxazole-4,6(5H,6aH)-dione chemical structure, C24H19FN2O3, CAS 353793-09-6

3-(4-Fluorophenyl)-2-phenyl-5-(p-tolyl)dihydro-2H-pyrrolo[3,4-d]isoxazole-4,6(5H,6aH)-dione

CAS 353793-09-6C₂₄H₁₉FN₂O₃

5-(2-Methoxyphenyl)-3-(3-nitrophenyl)-2-phenyl-hexahydro-2H-pyrrolo[3,4-d][1,2]oxazole-4,6-dione chemical structure, C24H19N3O6, CAS 301534-56-5

5-(2-Methoxyphenyl)-3-(3-nitrophenyl)-2-phenyl-hexahydro-2H-pyrrolo[3,4-d][1,2]oxazole-4,6-dione

CAS 301534-56-5C₂₄H₁₉N₃O₆

5-(2-Chlorophenyl)-3-(4-methoxyphenyl)-2-phenyldihydro-2H-pyrrolo(3,4-D)isoxazole-4,6(3H,5H)-dione chemical structure, C24H19ClN2O4, CAS 301534-55-4

5-(2-Chlorophenyl)-3-(4-methoxyphenyl)-2-phenyldihydro-2H-pyrrolo(3,4-D)isoxazole-4,6(3H,5H)-dione

CAS 301534-55-4C₂₄H₁₉ClN₂O₄

3-(2,4-Dichlorophenyl)-5-(4-methoxyphenyl)-2-phenyl-hexahydro-2H-pyrrolo[3,4-d][1,2]oxazole-4,6-dione chemical structure, C24H18Cl2N2O4, CAS 353273-78-6

3-(2,4-Dichlorophenyl)-5-(4-methoxyphenyl)-2-phenyl-hexahydro-2H-pyrrolo[3,4-d][1,2]oxazole-4,6-dione

CAS 353273-78-6C₂₄H₁₈Cl₂N₂O₄

3-(3-Bromophenyl)-2,5-diphenyldihydro-2H-pyrrolo[3,4-d]isoxazole-4,6(5H,6aH)-dione chemical structure, C23H17BrN2O3, CAS 342608-75-7

3-(3-Bromophenyl)-2,5-diphenyldihydro-2H-pyrrolo[3,4-d]isoxazole-4,6(5H,6aH)-dione

CAS 342608-75-7C₂₃H₁₇BrN₂O₃

3-(3-Nitro-phenyl)-2,5-diphenyl-tetrahydro-pyrrolo[3,4-d]isoxazole-4,6-dione chemical structure, C23H17N3O5, CAS 469890-59-3

3-(3-Nitro-phenyl)-2,5-diphenyl-tetrahydro-pyrrolo[3,4-d]isoxazole-4,6-dione

CAS 469890-59-3C₂₃H₁₇N₃O₅

5-(4-Fluorophenyl)-3-(4-methoxyphenyl)-2-phenyldihydro-2H-pyrrolo[3,4-d]isoxazole-4,6(3H,5H)-dione chemical structure, C24H19FN2O4, CAS 312713-64-7

5-(4-Fluorophenyl)-3-(4-methoxyphenyl)-2-phenyldihydro-2H-pyrrolo[3,4-d]isoxazole-4,6(3H,5H)-dione

CAS 312713-64-7C₂₄H₁₉FN₂O₄

3-(3-Bromophenyl)-5-(2-methoxyphenyl)-2-(2-methylphenyl)dihydro-2H-pyrrolo[3,4-d]isoxazole-4,6(3H,5H)-dione chemical structure, C25H21BrN2O4, CAS 317330-48-6

3-(3-Bromophenyl)-5-(2-methoxyphenyl)-2-(2-methylphenyl)dihydro-2H-pyrrolo[3,4-d]isoxazole-4,6(3H,5H)-dione

CAS 317330-48-6C₂₅H₂₁BrN₂O₄

3-(5-Bromo-2-hydroxyphenyl)-2-phenyl-5-(p-tolyl)dihydro-2H-pyrrolo[3,4-d]isoxazole-4,6(5H,6aH)-dione chemical structure, C24H19BrN2O4, CAS 470469-21-7

3-(5-Bromo-2-hydroxyphenyl)-2-phenyl-5-(p-tolyl)dihydro-2H-pyrrolo[3,4-d]isoxazole-4,6(5H,6aH)-dione

CAS 470469-21-7C₂₄H₁₉BrN₂O₄

5-(4-Methoxyphenyl)-2,3-diphenyl-hexahydro-2H-pyrrolo[3,4-d][1,2]oxazole-4,6-dione chemical structure, C24H20N2O4, CAS 470469-26-2

5-(4-Methoxyphenyl)-2,3-diphenyl-hexahydro-2H-pyrrolo[3,4-d][1,2]oxazole-4,6-dione

CAS 470469-26-2C₂₄H₂₀N₂O₄

3-(5-Bromo-2-hydroxyphenyl)-2,5-diphenyldihydro-2H-pyrrolo[3,4-d]isoxazole-4,6(5H,6aH)-dione chemical structure, C23H17BrN2O4, CAS 352665-97-5

3-(5-Bromo-2-hydroxyphenyl)-2,5-diphenyldihydro-2H-pyrrolo[3,4-d]isoxazole-4,6(5H,6aH)-dione

CAS 352665-97-5C₂₃H₁₇BrN₂O₄

3-(5-Bromo-2-hydroxyphenyl)-2-(4-chlorophenyl)-5-(4-methoxyphenyl)dihydro-2H-pyrrolo[3,4-d]isoxazole-4,6(5H,6aH)-dione chemical structure, C24H18BrClN2O5, CAS 470692-71-8

3-(5-Bromo-2-hydroxyphenyl)-2-(4-chlorophenyl)-5-(4-methoxyphenyl)dihydro-2H-pyrrolo[3,4-d]isoxazole-4,6(5H,6aH)-dione

CAS 470692-71-8C₂₄H₁₈BrClN₂O₅

2-(4-Chlorophenyl)-5-(4-methoxyphenyl)-3-(3-nitrophenyl)dihydro-2H-pyrrolo[3,4-d]isoxazole-4,6(5H,6aH)-dione chemical structure, C24H18ClN3O6, CAS 354760-98-8

2-(4-Chlorophenyl)-5-(4-methoxyphenyl)-3-(3-nitrophenyl)dihydro-2H-pyrrolo[3,4-d]isoxazole-4,6(5H,6aH)-dione

CAS 354760-98-8C₂₄H₁₈ClN₃O₆

2-(4-Chlorophenyl)-3-(4-methoxyphenyl)-5-(4-methylphenyl)-hexahydro-2H-pyrrolo[3,4-d][1,2]oxazole-4,6-dione chemical structure, C25H21ClN2O4, CAS 356568-13-3

2-(4-Chlorophenyl)-3-(4-methoxyphenyl)-5-(4-methylphenyl)-hexahydro-2H-pyrrolo[3,4-d][1,2]oxazole-4,6-dione

CAS 356568-13-3C₂₅H₂₁ClN₂O₄

3-(4-Fluorophenyl)-5-(4-methoxyphenyl)-2-phenyl-hexahydro-2H-pyrrolo[3,4-d][1,2]oxazole-4,6-dione chemical structure, C24H19FN2O4, CAS 306969-39-1

3-(4-Fluorophenyl)-5-(4-methoxyphenyl)-2-phenyl-hexahydro-2H-pyrrolo[3,4-d][1,2]oxazole-4,6-dione

CAS 306969-39-1C₂₄H₁₉FN₂O₄

2-(4-Chlorophenyl)-3-[4-(dimethylamino)phenyl]-5-phenyl-hexahydro-2H-pyrrolo[3,4-d][1,2]oxazole-4,6-dione chemical structure, C25H22ClN3O3, CAS 306969-52-8

2-(4-Chlorophenyl)-3-[4-(dimethylamino)phenyl]-5-phenyl-hexahydro-2H-pyrrolo[3,4-d][1,2]oxazole-4,6-dione

CAS 306969-52-8C₂₅H₂₂ClN₃O₃