Murcko scaffold
Ring system with 3 rings and 18 atoms
6 chemicals on CompoundList share this ring system.
- Rings
- 3
- Scaffold atoms
- 18
- Chemicals
- 6
- With full pages
- 2
Scaffold SMILES
C=C1CC2OC(=O)C(=C)C2CCC2OC1=CC2=O
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 6 of 6 chemicals
Isogoiazensolide
CAS 217086-55-0C19H20O7
Isocentratherin
CAS 80377-52-2C20H22O7
![(3aR,4S,6R,11S,11aS)-11-Hydroxy-6-methyl-3,10-dimethylene-2,7-dioxo-2,3,3a,4,5,6,7,10,11,11a-decahydro-6,9-epoxycyclodeca[b]furan-4-yl methacrylate chemical structure, C19H20O7, CAS 167697-34-9](/s/QOLGSSCWXRXSJG-QFNWCWRCSA-N.svg)
(3aR,4S,6R,11S,11aS)-11-Hydroxy-6-methyl-3,10-dimethylene-2,7-dioxo-2,3,3a,4,5,6,7,10,11,11a-decahydro-6,9-epoxycyclodeca[b]furan-4-yl methacrylate
CAS 167697-34-9C19H20O7
4,15-Isoatriplicolide methylacrylate
CAS 133559-38-3C19H20O6
Isoatriplicolide tiglate
CAS 133559-39-4C20H22O6
![(3aR,4R,6R,11R,11aS)-11-Hydroxy-6-methyl-3,10-dimethylene-2,7-dioxo-2,3,3a,4,5,6,7,10,11,11a-decahydro-6,9-epoxycyclodeca[b]furan-4-yl methacrylate chemical structure, C19H20O7, CAS 1578155-10-8](/s/QOLGSSCWXRXSJG-KZYVRXGSSA-N.svg)
(3aR,4R,6R,11R,11aS)-11-Hydroxy-6-methyl-3,10-dimethylene-2,7-dioxo-2,3,3a,4,5,6,7,10,11,11a-decahydro-6,9-epoxycyclodeca[b]furan-4-yl methacrylate
CAS 1578155-10-8C19H20O7
Related scaffolds
Same ring framework with different atoms or bond orders
