Murcko scaffold

2-{[3-(2-Furylmethyl)-4-oxo-3,4-dihydro[1]benzofuro[3,2-d]pyrimidin-2-yl]thio}-N-phenylacetamide scaffold

28 chemicals on CompoundList share this ring system.

Rings: 5
Scaffold atoms: 31
Chemicals: 28
With full pages: 6

Scaffold SMILES

O=C(CSc1nc2c(oc3ccccc32)c(=O)n1Cc1ccco1)Nc1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold Open the 2-{[3-(2-Furylmethyl)-4-oxo-3,4-dihydro[1]benzofuro[3,2-d]pyrimidin-2-yl]thio}-N-phenylacetamide page

Murcko scaffold O=C(CSc1nc2c(oc3ccccc32)c(=O)n1Cc1ccco1)Nc1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 28 of 28 chemicals

N-(3-Fluoro-4-methylphenyl)-2-((3-(furan-2-ylmethyl)-4-oxo-3,4-dihydrobenzofuro[3,2-d]pyrimidin-2-yl)thio)acetamide

CAS 892300-46-8C₂₄H₁₈FN₃O₄S

2-{[3-(2-Furylmethyl)-4-oxo-3,4-dihydro[1]benzofuro[3,2-d]pyrimidin-2-yl]thio}-N-phenylacetamide

CAS 902903-77-9C₂₃H₁₇N₃O₄S

2-((3-(Furan-2-ylmethyl)-4-oxo-3,4-dihydrobenzofuro[3,2-d]pyrimidin-2-yl)thio)-N-(o-tolyl)acetamide

CAS 902903-81-5C₂₄H₁₉N₃O₄S

2-{[3-(2-Furylmethyl)-4-oxo-3,4-dihydro[1]benzofuro[3,2-d]pyrimidin-2-yl]thio}-N-(3-methylphenyl)acetamide

CAS 902903-85-9C₂₄H₁₉N₃O₄S

2-{[3-(2-Furylmethyl)-4-oxo-3,4-dihydro[1]benzofuro[3,2-d]pyrimidin-2-yl]thio}-N-(4-methylphenyl)acetamide

CAS 902903-89-3C₂₄H₁₉N₃O₄S

N-(2-Chlorophenyl)-2-{[3-(2-furylmethyl)-4-oxo-3,4-dihydro[1]benzofuro[3,2-d]pyrimidin-2-yl]thio}acetamide

CAS 902903-93-9C₂₃H₁₆ClN₃O₄S

N-(3-Chlorophenyl)-2-{[3-(2-furylmethyl)-4-oxo-3,4-dihydro[1]benzofuro[3,2-d]pyrimidin-2-yl]thio}acetamide

CAS 902903-97-3C₂₃H₁₆ClN₃O₄S

N-(3-Chloro-4-methoxyphenyl)-2-{[3-(2-furylmethyl)-4-oxo-3,4-dihydro[1]benzofuro[3,2-d]pyrimidin-2-yl]thio}acetamide

CAS 902904-61-4C₂₄H₁₈ClN₃O₅S

N-(2,3-Dimethylphenyl)-2-{[3-(2-furylmethyl)-4-oxo-3,4-dihydro[1]benzofuro[3,2-d]pyrimidin-2-yl]thio}acetamide

CAS 902904-29-4C₂₅H₂₁N₃O₄S

2-{[3-(Furan-2-ylmethyl)-4-oxo-3,4-dihydro[1]benzofuro[3,2-d]pyrimidin-2-yl]sulfanyl}-N-[2-(trifluoromethyl)phenyl]acetamide

CAS 902904-53-4C₂₄H₁₆F₃N₃O₄S

2-{[3-(Furan-2-ylmethyl)-4-oxo-3,4-dihydro[1]benzofuro[3,2-d]pyrimidin-2-yl]sulfanyl}-N-[3-(methylsulfanyl)phenyl]acetamide

CAS 902937-93-3C₂₄H₁₉N₃O₄S₂

N-(3,4-Dimethoxyphenyl)-2-{[3-(2-furylmethyl)-4-oxo-3,4-dihydro[1]benzofuro[3,2-d]pyrimidin-2-yl]thio}acetamide

CAS 902938-03-8C₂₅H₂₁N₃O₆S

Ethyl 2-(2-((3-(furan-2-ylmethyl)-4-oxo-3,4-dihydrobenzofuro[3,2-d]pyrimidin-2-yl)thio)acetamido)benzoate

CAS 893786-01-1C₂₆H₂₁N₃O₆S

2-((3-(Furan-2-ylmethyl)-4-oxo-3,4-dihydrobenzofuro[3,2-d]pyrimidin-2-yl)thio)-N-(4-methoxyphenyl)acetamide

CAS 902904-09-0C₂₄H₁₉N₃O₅S

N-(2-Fluorophenyl)-2-{[3-(2-furylmethyl)-4-oxo-3,4-dihydro[1]benzofuro[3,2-d]pyrimidin-2-yl]thio}acetamide

CAS 902904-13-6C₂₃H₁₆FN₃O₄S

N-(4-Fluorophenyl)-2-((3-(furan-2-ylmethyl)-4-oxo-3,4-dihydrobenzofuro[3,2-d]pyrimidin-2-yl)thio)acetamide

CAS 902904-17-0C₂₃H₁₆FN₃O₄S

N-(3,4-Dimethylphenyl)-2-{[3-(2-furylmethyl)-4-oxo-3,4-dihydro[1]benzofuro[3,2-d]pyrimidin-2-yl]thio}acetamide

CAS 902904-21-6C₂₅H₂₁N₃O₄S

$N-(3,5-Dimethylphenyl)-2-({5-[(furan-2-yl)methyl]-6-oxo-8-oxa-3,5-diazatricyclo[7.4.0.0^{2,7}]trideca-1(9),2(7),3,10,12-pentaen-4-yl}sulfanyl)acetamide chemical structure, C25H21N3O4S, CAS 902904-25-0$