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Murcko scaffold

1-(4-Phenyl-1,3-thiazol-2-yl)piperidine scaffold

34 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
17
Chemicals
34
With full pages
8
Scaffold SMILES

c1ccc(-c2csc(N3CCCCC3)n2)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 1-(4-Phenyl-1,3-thiazol-2-yl)piperidine page
Murcko scaffold c1ccc(-c2csc(N3CCCCC3)n2)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 34 of 34 chemicals

1-[4-(2,4-Dichlorophenyl)-1,3-thiazol-2-yl]piperidine-4-carboxamide chemical structure, C15H15Cl2N3OS, CAS 447431-12-1
1-[4-(2,4-Dichlorophenyl)-1,3-thiazol-2-yl]piperidine-4-carboxamide
CAS 447431-12-1C15H15Cl2N3OS
1-[4-(4-Fluorophenyl)-1,3-thiazol-2-yl]piperidine-4-carboxylic acid chemical structure, C15H15FN2O2S, CAS 381193-57-3
1-[4-(4-Fluorophenyl)-1,3-thiazol-2-yl]piperidine-4-carboxylic acid
CAS 381193-57-3C15H15FN2O2S
4-(4-Bromophenyl)-2-(4-methylpiperidin-1-yl)thiazole chemical structure, C15H17BrN2S, CAS 346641-89-2
4-(4-Bromophenyl)-2-(4-methylpiperidin-1-yl)thiazole
CAS 346641-89-2C15H17BrN2S
1-(4-Phenyl-5-propyl-1,3-thiazol-2-yl)piperidine-4-carboxamide chemical structure, C18H23N3OS, CAS 309266-49-7
1-(4-Phenyl-5-propyl-1,3-thiazol-2-yl)piperidine-4-carboxamide
CAS 309266-49-7C18H23N3OS
1-(4-(4-Chlorophenyl)thiazol-2-yl)piperidine-4-carboxylic acid chemical structure, C15H15ClN2O2S, CAS 345990-26-3
1-(4-(4-Chlorophenyl)thiazol-2-yl)piperidine-4-carboxylic acid
CAS 345990-26-3C15H15ClN2O2S
1-(4-Phenylthiazol-2-yl)piperidine-4-carboxylic acid chemical structure, C15H16N2O2S, CAS 299922-24-0
1-(4-Phenylthiazol-2-yl)piperidine-4-carboxylic acid
CAS 299922-24-0C15H16N2O2S
1-[4-(4-Nitrophenyl)-1,3-thiazol-2-yl]piperidine-4-carboxamide chemical structure, C15H16N4O3S, CAS 345987-67-9
1-[4-(4-Nitrophenyl)-1,3-thiazol-2-yl]piperidine-4-carboxamide
CAS 345987-67-9C15H16N4O3S
4-(4-Chlorophenyl)-2-(4-methylpiperidin-1-yl)thiazole chemical structure, C15H17ClN2S, CAS 345987-48-6
4-(4-Chlorophenyl)-2-(4-methylpiperidin-1-yl)thiazole
CAS 345987-48-6C15H17ClN2S
2-(4-Methylpiperidin-1-yl)-4-phenylthiazole chemical structure, C15H18N2S, CAS 345990-52-5
2-(4-Methylpiperidin-1-yl)-4-phenylthiazole
CAS 345990-52-5C15H18N2S
1-[4-(2,5-Dimethoxyphenyl)-1,3-thiazol-2-yl]piperidine-4-carboxamide chemical structure, C17H21N3O3S, CAS 540515-32-0
1-[4-(2,5-Dimethoxyphenyl)-1,3-thiazol-2-yl]piperidine-4-carboxamide
CAS 540515-32-0C17H21N3O3S
1-(4-Phenyl-1,3-thiazol-2-yl)piperidine chemical structure, C14H16N2S, CAS 34587-25-2
1-(4-Phenyl-1,3-thiazol-2-yl)piperidine
CAS 34587-25-2C14H16N2S
1-[4-(4-Bromophenyl)-2-thiazolyl]-4-piperidinecarboxamide chemical structure, C15H16BrN3OS, CAS 361371-42-8
1-[4-(4-Bromophenyl)-2-thiazolyl]-4-piperidinecarboxamide
CAS 361371-42-8C15H16BrN3OS
4-Phenyl-2-(piperidin-1-yl)-1,3-thiazole-5-carbaldehyde chemical structure, C15H16N2OS, CAS 65358-80-7
4-Phenyl-2-(piperidin-1-yl)-1,3-thiazole-5-carbaldehyde
CAS 65358-80-7C15H16N2OS
4-(4-Bromophenyl)-2-(piperidin-1-yl)thiazole chemical structure, C14H15BrN2S, CAS 125488-16-6
4-(4-Bromophenyl)-2-(piperidin-1-yl)thiazole
CAS 125488-16-6C14H15BrN2S
1-(4-(4-Bromophenyl)thiazol-2-yl)piperidine-4-carboxylic acid chemical structure, C15H15BrN2O2S, CAS 296899-02-0
1-(4-(4-Bromophenyl)thiazol-2-yl)piperidine-4-carboxylic acid
CAS 296899-02-0C15H15BrN2O2S
1-[4-(3-Nitrophenyl)-1,3-thiazol-2-yl]piperidine-4-carboxylic acid chemical structure, C15H15N3O4S, CAS 361371-27-9
1-[4-(3-Nitrophenyl)-1,3-thiazol-2-yl]piperidine-4-carboxylic acid
CAS 361371-27-9C15H15N3O4S
1-[4-(4-Chlorophenyl)-1,3-thiazol-2-yl]-N-(2-hydroxyethyl)-4-piperidinecarboxamide chemical structure, C17H20ClN3O2S, CAS 1033463-18-1
1-[4-(4-Chlorophenyl)-1,3-thiazol-2-yl]-N-(2-hydroxyethyl)-4-piperidinecarboxamide
CAS 1033463-18-1C17H20ClN3O2S
1-(4-Phenyl-1,3-thiazol-2-yl)piperidine hydrochloride chemical structure, C14H17ClN2S, CAS 68981-16-8
1-(4-Phenyl-1,3-thiazol-2-yl)piperidine hydrochloride
CAS 68981-16-8C14H17ClN2S
1-(4-Phenyl-1,3-thiazol-2-yl)-3-piperidinecarboxylic acid chemical structure, C15H16N2O2S, CAS 927803-58-5
1-(4-Phenyl-1,3-thiazol-2-yl)-3-piperidinecarboxylic acid
CAS 927803-58-5C15H16N2O2S
4-[2-(4,4-Difluoropiperidin-1-yl)-1,3-thiazol-4-yl]benzoic acid chemical structure, C15H14F2N2O2S, CAS 860344-58-7
4-[2-(4,4-Difluoropiperidin-1-yl)-1,3-thiazol-4-yl]benzoic acid
CAS 860344-58-7C15H14F2N2O2S
4-(2-Piperidin-1-yl-thiazol-4-yl)-benzoic acid chemical structure, C15H16N2O2S, CAS 860344-52-1
4-(2-Piperidin-1-yl-thiazol-4-yl)-benzoic acid
CAS 860344-52-1C15H16N2O2S
Ethyl 1-[4-(2-hydroxyphenyl)-2-thiazolyl]-4-piperidinecarboxylate chemical structure, C17H20N2O3S, CAS 1207618-18-5
Ethyl 1-[4-(2-hydroxyphenyl)-2-thiazolyl]-4-piperidinecarboxylate
CAS 1207618-18-5C17H20N2O3S
Ethyl 1-[4-(3-nitrophenyl)-1,3-thiazol-2-yl]piperidine-4-carboxylate chemical structure, C17H19N3O4S, CAS 1312573-00-4
Ethyl 1-[4-(3-nitrophenyl)-1,3-thiazol-2-yl]piperidine-4-carboxylate
CAS 1312573-00-4C17H19N3O4S
Ethyl 1-[4-(3-aminophenyl)-1,3-thiazol-2-yl]piperidine-4-carboxylate chemical structure, C17H21N3O2S, CAS 1312573-01-5
Ethyl 1-[4-(3-aminophenyl)-1,3-thiazol-2-yl]piperidine-4-carboxylate
CAS 1312573-01-5C17H21N3O2S