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Murcko scaffold

Ring system with 3 rings and 24 atoms

6 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
24
Chemicals
6
With full pages
5
Scaffold SMILES

O=C(CNC(=O)c1ccccc1)NN=Cc1ccc2c(c1)OCO2

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(CNC(=O)c1ccccc1)NN=Cc1ccc2c(c1)OCO2

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 6 of 6 chemicals

N-(2-(2-(1,3-Benzodioxol-5-ylmethylene)hydrazino)-2-oxoethyl)-3-bromobenzamide chemical structure, C17H14BrN3O4, CAS 324014-83-7
N-(2-(2-(1,3-Benzodioxol-5-ylmethylene)hydrazino)-2-oxoethyl)-3-bromobenzamide
CAS 324014-83-7C17H14BrN3O4
N-[2-[(2E)-2-(1,3-Benzodioxol-5-ylmethylidene)hydrazinyl]-2-oxoethyl]-3,4-dimethoxybenzamide chemical structure, C19H19N3O6, CAS 324014-91-7
N-[2-[(2E)-2-(1,3-Benzodioxol-5-ylmethylidene)hydrazinyl]-2-oxoethyl]-3,4-dimethoxybenzamide
CAS 324014-91-7C19H19N3O6
N-(2-(2-(1,3-Benzodioxol-5-ylmethylene)hydrazino)-2-oxoethyl)-4-methylbenzamide chemical structure, C18H17N3O4, CAS 443968-13-6
N-(2-(2-(1,3-Benzodioxol-5-ylmethylene)hydrazino)-2-oxoethyl)-4-methylbenzamide
CAS 443968-13-6C18H17N3O4
N-(2-(2-(1,3-Benzodioxol-5-ylmethylene)hydrazino)-2-oxoethyl)-4-fluorobenzamide chemical structure, C17H14FN3O4, CAS 324014-85-9
N-(2-(2-(1,3-Benzodioxol-5-ylmethylene)hydrazino)-2-oxoethyl)-4-fluorobenzamide
CAS 324014-85-9C17H14FN3O4
N-(2-(2-(1,3-Benzodioxol-5-ylmethylene)hydrazino)-2-oxoethyl)-2-methylbenzamide chemical structure, C18H17N3O4, CAS 444656-53-5
N-(2-(2-(1,3-Benzodioxol-5-ylmethylene)hydrazino)-2-oxoethyl)-2-methylbenzamide
CAS 444656-53-5C18H17N3O4
N-(2-(2-(1,3-Benzodioxol-5-ylmethylene)hydrazino)-2-oxoethyl)-4-methoxybenzamide chemical structure, C18H17N3O5, CAS 444767-33-3
N-(2-(2-(1,3-Benzodioxol-5-ylmethylene)hydrazino)-2-oxoethyl)-4-methoxybenzamide
CAS 444767-33-3C18H17N3O5