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Murcko scaffold

2-Benzylidene-3-quinuclidinone scaffold

39 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
16
Chemicals
39
With full pages
8
Scaffold SMILES

O=C1C(=Cc2ccccc2)N2CCC1CC2

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 2-Benzylidene-3-quinuclidinone page
Murcko scaffold O=C1C(=Cc2ccccc2)N2CCC1CC2

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 39 of 39 chemicals

2-Benzylidene-3-quinuclidinone chemical structure, C14H15NO, CAS 24123-89-5
2-Benzylidene-3-quinuclidinone
CAS 24123-89-5C14H15NO
(2E)-2-[(2-Chlorophenyl)methylidene]-1-azabicyclo[2.2.2]octan-3-one chemical structure, C14H14ClNO, CAS 106218-50-2
(2E)-2-[(2-Chlorophenyl)methylidene]-1-azabicyclo[2.2.2]octan-3-one
CAS 106218-50-2C14H14ClNO
1-Azabicyclo[2.2.2]octan-3-one, 2-[(2-chlorophenyl)methylene]-, (Z)- chemical structure, C14H14ClNO, CAS 103660-35-1
1-Azabicyclo[2.2.2]octan-3-one, 2-[(2-chlorophenyl)methylene]-, (Z)-
CAS 103660-35-1C14H14ClNO
(2E)-2-(3-Chlorobenzylidene)-1-azabicyclo[2.2.2]octan-3-one chemical structure, C14H14ClNO, CAS 102269-56-7
(2E)-2-(3-Chlorobenzylidene)-1-azabicyclo[2.2.2]octan-3-one
CAS 102269-56-7C14H14ClNO
(2Z)-2-[(4-Fluorophenyl)methylidene]-1-azabicyclo[2.2.2]octan-3-one chemical structure, C14H14FNO, CAS 209863-77-4
(2Z)-2-[(4-Fluorophenyl)methylidene]-1-azabicyclo[2.2.2]octan-3-one
CAS 209863-77-4C14H14FNO
(2E)-2-(3-Bromobenzylidene)-1-azabicyclo[2.2.2]octan-3-one chemical structure, C14H14BrNO, CAS 299440-56-5
(2E)-2-(3-Bromobenzylidene)-1-azabicyclo[2.2.2]octan-3-one
CAS 299440-56-5C14H14BrNO
(2E)-2-(2,3-Dichlorobenzylidene)-1-azabicyclo[2.2.2]octan-3-one chemical structure, C14H13Cl2NO, CAS 315244-81-6
(2E)-2-(2,3-Dichlorobenzylidene)-1-azabicyclo[2.2.2]octan-3-one
CAS 315244-81-6C14H13Cl2NO
2-{(Z)-[4-(Trifluoromethyl)phenyl]methylidene}-3-quinuclidinone chemical structure, C15H14F3NO, CAS 52407-95-1
2-{(Z)-[4-(Trifluoromethyl)phenyl]methylidene}-3-quinuclidinone
CAS 52407-95-1C15H14F3NO
(2Z)-2-(2-Methoxybenzylidene)-1-azabicyclo[2.2.2]octan-3-one chemical structure, C15H17NO2, CAS 6047-31-0
(2Z)-2-(2-Methoxybenzylidene)-1-azabicyclo[2.2.2]octan-3-one
CAS 6047-31-0C15H17NO2
(2Z)-2-[(2-Chloro-6-fluorophenyl)methylidene]-1-azabicyclo[2.2.2]octan-3-one chemical structure, C14H13ClFNO, CAS 477848-49-0
(2Z)-2-[(2-Chloro-6-fluorophenyl)methylidene]-1-azabicyclo[2.2.2]octan-3-one
CAS 477848-49-0C14H13ClFNO
2-(4-Chlorobenzylidene)quinuclidin-3-one chemical structure, C14H14ClNO, CAS 54529-43-0
2-(4-Chlorobenzylidene)quinuclidin-3-one
CAS 54529-43-0C14H14ClNO
(2E)-2-[(4-Methoxyphenyl)methylidene]-1-azabicyclo[2.2.2]octan-3-one chemical structure, C15H17NO2, CAS 52407-93-9
(2E)-2-[(4-Methoxyphenyl)methylidene]-1-azabicyclo[2.2.2]octan-3-one
CAS 52407-93-9C15H17NO2
2-[(4-Methoxyphenyl)methylene]-3-quinuclidinone chemical structure, C15H17NO2
2-[(4-Methoxyphenyl)methylene]-3-quinuclidinone
C15H17NO2
2-(4-Nitrobenzylidene)quinuclidin-3-one chemical structure, C14H14N2O3, CAS 79331-03-6
2-(4-Nitrobenzylidene)quinuclidin-3-one
CAS 79331-03-6C14H14N2O3
2-[(4-Nitrophenyl)methylene]-3-quinuclidinone chemical structure, C14H14N2O3, CAS 78961-43-0
2-[(4-Nitrophenyl)methylene]-3-quinuclidinone
CAS 78961-43-0C14H14N2O3
2-Benzylidenequinuclidin-3-one chemical structure, C14H15NO, CAS 52455-72-8
2-Benzylidenequinuclidin-3-one
CAS 52455-72-8C14H15NO
(Z)-2-Benzylidenequinuclidin-3-one chemical structure, C14H15NO, CAS 52455-71-7
(Z)-2-Benzylidenequinuclidin-3-one
CAS 52455-71-7C14H15NO
2-{[4-(Dimethylamino)phenyl]methylene}-3-quinuclidinone chemical structure, C16H20N2O, CAS 112611-39-9
2-{[4-(Dimethylamino)phenyl]methylene}-3-quinuclidinone
CAS 112611-39-9C16H20N2O
3-{[4-(Dimethylamino)phenyl]methylene}-4-azabicyclo[2.2.2]octan-2-one chemical structure, C16H20N2O, CAS 196712-97-7
3-{[4-(Dimethylamino)phenyl]methylene}-4-azabicyclo[2.2.2]octan-2-one
CAS 196712-97-7C16H20N2O
(2E)-2-[(3,4-Dichlorophenyl)methylidene]-1-azabicyclo[2.2.2]octan-3-one chemical structure, C14H13Cl2NO, CAS 102269-54-5
(2E)-2-[(3,4-Dichlorophenyl)methylidene]-1-azabicyclo[2.2.2]octan-3-one
CAS 102269-54-5C14H13Cl2NO
2-(2,6-Dichlorobenzylidene)quinuclidin-3-one chemical structure, C14H13Cl2NO, CAS 53898-73-0
2-(2,6-Dichlorobenzylidene)quinuclidin-3-one
CAS 53898-73-0C14H13Cl2NO
(2Z)-2-[(3-Nitrophenyl)methylidene]-1-azabicyclo[2.2.2]octan-3-one chemical structure, C14H14N2O3, CAS 875299-80-2
(2Z)-2-[(3-Nitrophenyl)methylidene]-1-azabicyclo[2.2.2]octan-3-one
CAS 875299-80-2C14H14N2O3
2-(3-Hydroxybenzylidene)quinuclidin-3-one chemical structure, C14H15NO2, CAS 196712-94-4
2-(3-Hydroxybenzylidene)quinuclidin-3-one
CAS 196712-94-4C14H15NO2
(2Z)-2-[(2,4-Dimethoxyphenyl)methylidene]-1-azabicyclo[2.2.2]octan-3-one chemical structure, C16H19NO3, CAS 209863-78-5
(2Z)-2-[(2,4-Dimethoxyphenyl)methylidene]-1-azabicyclo[2.2.2]octan-3-one
CAS 209863-78-5C16H19NO3