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Murcko scaffold

Ring system with 2 rings and 20 atoms

21 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
20
Chemicals
21
With full pages
8
Scaffold SMILES

O=C(C=Cc1ccccc1)NCCCc1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(C=Cc1ccccc1)NCCCc1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 21 of 21 chemicals

3-(4-Chlorophenyl)-N-(3-phenylpropyl)acrylamide chemical structure, C18H18ClNO, CAS 193219-50-0
3-(4-Chlorophenyl)-N-(3-phenylpropyl)acrylamide
CAS 193219-50-0C18H18ClNO
3-(4-Isopropylphenyl)-N-(3-phenylpropyl)acrylamide chemical structure, C21H25NO, CAS 1164519-34-9
3-(4-Isopropylphenyl)-N-(3-phenylpropyl)acrylamide
CAS 1164519-34-9C21H25NO
3-(3,4-Dimethoxyphenyl)-N-(3-phenylpropyl)acrylamide chemical structure, C20H23NO3, CAS 1164519-26-9
3-(3,4-Dimethoxyphenyl)-N-(3-phenylpropyl)acrylamide
CAS 1164519-26-9C20H23NO3
3-(4-Methylphenyl)-N-(3-phenylpropyl)acrylamide chemical structure, C19H21NO, CAS 1164534-30-8
3-(4-Methylphenyl)-N-(3-phenylpropyl)acrylamide
CAS 1164534-30-8C19H21NO
3-(4-Bromophenyl)-N-(3-phenylpropyl)acrylamide chemical structure, C18H18BrNO, CAS 545366-25-4
3-(4-Bromophenyl)-N-(3-phenylpropyl)acrylamide
CAS 545366-25-4C18H18BrNO
Tyrphostin AG 555 chemical structure, C19H18N2O3, CAS 133550-34-2
Tyrphostin AG 555
CAS 133550-34-2C19H18N2O3
(E)-N-(4-Phenylbutan-2-yl)-3-(3,4,5-trimethoxyphenyl)prop-2-enamide chemical structure, C22H27NO4, CAS 1164491-58-0
(E)-N-(4-Phenylbutan-2-yl)-3-(3,4,5-trimethoxyphenyl)prop-2-enamide
CAS 1164491-58-0C22H27NO4
(E)-3-(4-Bromophenyl)-N-(4-phenylbutan-2-yl)prop-2-enamide chemical structure, C19H20BrNO, CAS 546063-14-3
(E)-3-(4-Bromophenyl)-N-(4-phenylbutan-2-yl)prop-2-enamide
CAS 546063-14-3C19H20BrNO
(E)-3-(2,4-Dichlorophenyl)-N-(4-phenylbutan-2-yl)prop-2-enamide chemical structure, C19H19Cl2NO, CAS 546098-46-8
(E)-3-(2,4-Dichlorophenyl)-N-(4-phenylbutan-2-yl)prop-2-enamide
CAS 546098-46-8C19H19Cl2NO
(E)-3-(4-Methoxyphenyl)-N-(4-phenylbutan-2-yl)prop-2-enamide chemical structure, C20H23NO2, CAS 1164547-98-1
(E)-3-(4-Methoxyphenyl)-N-(4-phenylbutan-2-yl)prop-2-enamide
CAS 1164547-98-1C20H23NO2
3-(4-Fluorophenyl)-N-(1-methyl-3-phenylpropyl)acrylamide chemical structure, C19H20FNO, CAS 545371-08-2
3-(4-Fluorophenyl)-N-(1-methyl-3-phenylpropyl)acrylamide
CAS 545371-08-2C19H20FNO
(E)-3-(2-Nitrophenyl)-N-(4-phenylbutan-2-yl)prop-2-enamide chemical structure, C19H20N2O3, CAS 600123-98-6
(E)-3-(2-Nitrophenyl)-N-(4-phenylbutan-2-yl)prop-2-enamide
CAS 600123-98-6C19H20N2O3
(E)-2-Methyl-3-phenyl-N-(4-phenylbutan-2-yl)prop-2-enamide chemical structure, C20H23NO, CAS 587845-73-6
(E)-2-Methyl-3-phenyl-N-(4-phenylbutan-2-yl)prop-2-enamide
CAS 587845-73-6C20H23NO
(E)-3-(3,4-Dimethoxyphenyl)-N-(4-phenylbutan-2-yl)prop-2-enamide chemical structure, C21H25NO3, CAS 844900-58-9
(E)-3-(3,4-Dimethoxyphenyl)-N-(4-phenylbutan-2-yl)prop-2-enamide
CAS 844900-58-9C21H25NO3
SU 1498 chemical structure, C25H30N2O2, CAS 168835-82-3
SU 1498
CAS 168835-82-3C25H30N2O2
(2E)-2-Cyano-3-(4-hydroxyphenyl)-N-(3-phenylpropyl)prop-2-enamide chemical structure, C19H18N2O2, CAS 178925-66-1
(2E)-2-Cyano-3-(4-hydroxyphenyl)-N-(3-phenylpropyl)prop-2-enamide
CAS 178925-66-1C19H18N2O2
N-(2-Hydroxy-3-phenylpropyl)cinnamamide chemical structure, C18H19NO2, CAS 1351664-35-1
N-(2-Hydroxy-3-phenylpropyl)cinnamamide
CAS 1351664-35-1C18H19NO2
(E)-3-(2-Chlorophenyl)-N-(2-hydroxy-3-phenylpropyl)acrylamide chemical structure, C18H18ClNO2, CAS 1351663-47-2
(E)-3-(2-Chlorophenyl)-N-(2-hydroxy-3-phenylpropyl)acrylamide
CAS 1351663-47-2C18H18ClNO2
(E)-N-(2-Hydroxy-3-(4-methoxyphenyl)-2-methylpropyl)-3-(4-(methylthio)phenyl)acrylamide chemical structure, C21H25NO3S, CAS 1798981-43-7
(E)-N-(2-Hydroxy-3-(4-methoxyphenyl)-2-methylpropyl)-3-(4-(methylthio)phenyl)acrylamide
CAS 1798981-43-7C21H25NO3S
(E)-N-(2-Hydroxy-3-phenylpropyl)-3-(4-(methylthio)phenyl)acrylamide chemical structure, C19H21NO2S, CAS 1799268-41-9
(E)-N-(2-Hydroxy-3-phenylpropyl)-3-(4-(methylthio)phenyl)acrylamide
CAS 1799268-41-9C19H21NO2S
N-(3-(3-Chlorophenyl)-3-hydroxypropyl)cinnamamide chemical structure, C18H18ClNO2, CAS 2035019-55-5
N-(3-(3-Chlorophenyl)-3-hydroxypropyl)cinnamamide
CAS 2035019-55-5C18H18ClNO2