CompoundList
Sign in
Murcko scaffold

Ring system with 6 rings and 30 atoms

6 chemicals on CompoundList share this ring system.

Rings
6
Scaffold atoms
30
Chemicals
6
With full pages
3
Scaffold SMILES

O=C(Nc1ccccc1)c1ccc2c(c1)C1C3CCC(C3)C1C(c1ccccc1)N2

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(Nc1ccccc1)c1ccc2c(c1)C1C3CCC(C3)C1C(c1ccccc1)N2

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 6 of 6 chemicals

N-(2-Chlorophenyl)-6-phenyl-5,6,6a,7,8,9,10,10a-octahydro-7,10-methanophenanthridine-2-carboxamide chemical structure, C27H25ClN2O, CAS 1005108-02-0
N-(2-Chlorophenyl)-6-phenyl-5,6,6a,7,8,9,10,10a-octahydro-7,10-methanophenanthridine-2-carboxamide
CAS 1005108-02-0C27H25ClN2O
N-(4-Methoxyphenyl)-6-phenyl-5,6,6a,7,8,9,10,10a-octahydro-7,10-methanophenanthridine-2-carboxamide chemical structure, C28H28N2O2, CAS 1005243-13-9
N-(4-Methoxyphenyl)-6-phenyl-5,6,6a,7,8,9,10,10a-octahydro-7,10-methanophenanthridine-2-carboxamide
CAS 1005243-13-9C28H28N2O2
rac-(1R,2S,10R,11R,12S)-N-(4-Fluorophenyl)-10-phenyl-9-azatetracyclo[10.2.1.0^{2,11}.0^{3,8}]pentadeca-3,5,7-triene-5-carboxamide chemical structure, C27H25FN2O, CAS 2416218-93-2
rac-(1R,2S,10R,11R,12S)-N-(4-Fluorophenyl)-10-phenyl-9-azatetracyclo[10.2.1.0^{2,11}.0^{3,8}]pentadeca-3,5,7-triene-5-carboxamide
CAS 2416218-93-2C27H25FN2O
(1R,2S,10R,11R,12S)-N-(3,4-Dimethylphenyl)-10-phenyl-9-azatetracyclo[10.2.1.02,11.03,8]pentadeca-3(8),4,6-triene-5-carboxamide chemical structure, C29H30N2O, CAS 2361574-31-2
(1R,2S,10R,11R,12S)-N-(3,4-Dimethylphenyl)-10-phenyl-9-azatetracyclo[10.2.1.02,11.03,8]pentadeca-3(8),4,6-triene-5-carboxamide
CAS 2361574-31-2C29H30N2O
rac-(1R,2S,10R,11R,12S)-N-(3,4-Dimethylphenyl)-10-phenyl-9-azatetracyclo(10.2.1.0^(2,11).0^(3,8))pentadeca-3,5,7-triene-5-carboxamide chemical structure, C29H30N2O, CAS 2624109-46-0
rac-(1R,2S,10R,11R,12S)-N-(3,4-Dimethylphenyl)-10-phenyl-9-azatetracyclo(10.2.1.0^(2,11).0^(3,8))pentadeca-3,5,7-triene-5-carboxamide
CAS 2624109-46-0C29H30N2O
rac-(1R,2S,10R,11R,12S)-N-(4-Bromo-3-chlorophenyl)-10-phenyl-9-azatetracyclo(10.2.1.0^(2,11).0^(3,8))pentadeca-3,5,7-triene-5-carboxamide chemical structure, C27H24BrClN2O, CAS 2624109-05-1
rac-(1R,2S,10R,11R,12S)-N-(4-Bromo-3-chlorophenyl)-10-phenyl-9-azatetracyclo(10.2.1.0^(2,11).0^(3,8))pentadeca-3,5,7-triene-5-carboxamide
CAS 2624109-05-1C27H24BrClN2O