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Murcko scaffold

Ring system with 8 rings and 29 atoms

7 chemicals on CompoundList share this ring system.

Rings
8
Scaffold atoms
29
Chemicals
7
With full pages
3
Scaffold SMILES

O=C1Nc2c(ccc3c2C=CCO3)C12CC1CC34CCCN3C(=O)C1(C2)NC4=O

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C1Nc2c(ccc3c2C=CCO3)C12CC1CC34CCCN3C(=O)C1(C2)NC4=O

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 7 of 7 chemicals

Sclerotiamide chemical structure, C26H29N3O5, CAS 184025-39-6
Sclerotiamide
CAS 184025-39-6C26H29N3O5
Notoamide B chemical structure, C26H29N3O4, CAS 937791-52-1
Notoamide B
CAS 937791-52-1C26H29N3O4
Notoamide A chemical structure, C26H29N3O5, CAS 937810-92-9
Notoamide A
CAS 937810-92-9C26H29N3O5
Notoamide H chemical structure, C26H29N3O6, CAS 1092808-30-4
Notoamide H
CAS 1092808-30-4C26H29N3O6
(3S,7'S,9'R)-7,7,10',10'-Tetramethylspiro[1H-pyrano[2,3-g]indole-3,11'-3,13-diazatetracyclo[5.5.2.01,9.03,7]tetradecane]-2,2',14'-trione chemical structure, C26H29N3O4, CAS 1041767-77-4
(3S,7'S,9'R)-7,7,10',10'-Tetramethylspiro[1H-pyrano[2,3-g]indole-3,11'-3,13-diazatetracyclo[5.5.2.01,9.03,7]tetradecane]-2,2',14'-trione
CAS 1041767-77-4C26H29N3O4
(3R,7'R,9'S)-7,7,10',10'-Tetramethylspiro[1H-pyrano[2,3-g]indole-3,11'-3,13-diazatetracyclo[5.5.2.01,9.03,7]tetradecane]-2,2',14'-trione chemical structure, C26H29N3O4, CAS 1134155-01-3
(3R,7'R,9'S)-7,7,10',10'-Tetramethylspiro[1H-pyrano[2,3-g]indole-3,11'-3,13-diazatetracyclo[5.5.2.01,9.03,7]tetradecane]-2,2',14'-trione
CAS 1134155-01-3C26H29N3O4
(3S,7'R,9'R)-7,7,10',10'-Tetramethylspiro[1H-pyrano[2,3-g]indole-3,11'-3,13-diazatetracyclo[5.5.2.01,9.03,7]tetradecane]-2,2',14'-trione chemical structure, C26H29N3O4, CAS 1041767-79-6
(3S,7'R,9'R)-7,7,10',10'-Tetramethylspiro[1H-pyrano[2,3-g]indole-3,11'-3,13-diazatetracyclo[5.5.2.01,9.03,7]tetradecane]-2,2',14'-trione
CAS 1041767-79-6C26H29N3O4