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Murcko scaffold

Ring system with 4 rings and 21 atoms

6 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
21
Chemicals
6
With full pages
3
Scaffold SMILES

O=C1c2cc3ccccc3cc2C(=O)C2C(=O)C=CCC12

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C1c2cc3ccccc3cc2C(=O)C2C(=O)C=CCC12

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 6 of 6 chemicals

Methyl (6aR,7S,10aR)-6,6a,7,10,10a,11-hexahydro-6a,7,10a,12-tetrahydroxy-3,8-dimethoxy-1-methyl-6,10,11-trioxo-2-naphthacenecarboxylate chemical structure, C23H20O11, CAS 71135-22-3
Methyl (6aR,7S,10aR)-6,6a,7,10,10a,11-hexahydro-6a,7,10a,12-tetrahydroxy-3,8-dimethoxy-1-methyl-6,10,11-trioxo-2-naphthacenecarboxylate
CAS 71135-22-3C23H20O11
5838 Dni chemical structure, C23H20O11, CAS 146864-75-7
5838 Dni
CAS 146864-75-7C23H20O11
3-Demethoxy-3-ethoxytetracenomycin C chemical structure, C24H22O11, CAS 79495-72-0
3-Demethoxy-3-ethoxytetracenomycin C
CAS 79495-72-0C24H22O11
Methyl (6aR,7S,10aR)-6,6a,7,10,10a,11-hexahydro-6a,7,12-trihydroxy-3,8,10a-trimethoxy-1-methyl-6,10,11-trioxo-2-naphthacenecarboxylate chemical structure, C24H22O11, CAS 121245-07-6
Methyl (6aR,7S,10aR)-6,6a,7,10,10a,11-hexahydro-6a,7,12-trihydroxy-3,8,10a-trimethoxy-1-methyl-6,10,11-trioxo-2-naphthacenecarboxylate
CAS 121245-07-6C24H22O11
Elloramycinone chemical structure, C23H20O11, CAS 99524-25-1
Elloramycinone
CAS 99524-25-1C23H20O11
Tetracenomycin C, 6-chloro- chemical structure, C23H19ClO11, CAS 82277-60-9
Tetracenomycin C, 6-chloro-
CAS 82277-60-9C23H19ClO11