Murcko scaffold
Ring system with 4 rings and 19 atoms
44 chemicals on CompoundList share this ring system.
- Rings
- 4
- Scaffold atoms
- 19
- Chemicals
- 44
- With full pages
- 14
Scaffold SMILES
O=c1c2ccccc2oc2cc3c(cc12)C=CCO3
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 44 of 44 chemicals
Trapezifolixanthone
CAS 50816-23-4C23H22O5
Calabaxanthone
CAS 39011-96-6C24H24O5
Demethylcalabaxanthone
CAS 106897-03-4C23H22O5
6-Deoxyjacareubin
CAS 16265-56-8C18H14O5
Jacareubin
CAS 3811-29-8C18H14O6
Macluraxanthone
CAS 5848-14-6C23H22O6
Fuscaxanthone A
CAS 499777-91-2C29H32O6
2H,6H-Pyrano(3,2-b)xanthen-6-one, 7,12-dihydroxy-2,2-dimethyl-
CAS 82667-93-4C18H14O5
Mangostanin
CAS 35349-68-9C24H24O6
Osajaxanthone
CAS 1043-08-9C18H14O5
Manglexanthone
CAS 62326-62-9C24H24O6
Brasixanthone C
CAS 407622-63-3C23H22O7
Brasixanthone B
CAS 327041-73-6C23H22O5
Dulxanthone F
CAS 263249-30-5C21H20O7
Dulxanthone H
CAS 263249-36-1C22H22O8
Latisxanthone C
CAS 197447-32-8C28H30O6
Atroviridin
CAS 207984-34-7C18H14O6
Nigrolineaxanthone M
CAS 643026-14-6C23H24O6
Nigrolineaxanthone K
CAS 643026-12-4C23H22O5
Acetyl blancoxanthone
CAS 853105-08-5C25H24O6
Nigrolineaxanthone V
CAS 864516-31-4C24H24O6
Formoxanthone A
CAS 869880-32-0C23H22O6
Blancoxanthone
CAS 155566-36-2C23H22O5
Gaboxanthone
CAS 876171-25-4C25H26O7
- Dulxanthone E261896-23-5C22H22O7
- Dulxanthone G263249-33-8C22H22O8
- 5-O-Methylxanthone V1865205-02-3C24H24O6
- Gerontoxanthone B121825-53-4C23H22O6
- Termicalcicolanone A929548-30-1C23H22O6
- Butyraxanthone B1141754-81-5C28H30O6
- Staudtiixanthone B1149336-08-2C23H22O6
- O-Demethylforbexanthone92609-77-3C18H14O6
- Forbexanthone150527-30-3C19H16O6
- Allanxanthone E1169496-98-3C24H24O7
- 2,2-Dimethyl-6-oxo-2H,6H-pyrano[3,2-b]xanthene-5,8-diyl diacetate3257-09-8C22H18O7
- 7,12-Dimethoxy-2,2-dimethyl-2H,6H-pyrano[3,2-b]xanthen-6-one88147-98-2C20H18O5
- 2,2-Dimethyl-6-oxo-2H,6H-pyrano[3,2-b]xanthene-7,12-diyl diacetate88147-96-0C22H18O7
- 10-O-Methylmacluraxanthone856428-88-1C24H24O6
- Demethylmangostanin2289591-37-1C23H22O6
- 7-Prenyljacareubin94513-60-7C23H22O6
- Garcinexanthone G2170885-47-7C23H22O7
- Xanthone V1103339-69-1C24H26O7
- Garcimangosxanthone F1632448-64-6C28H32O7
- 5,8,9-Trihydroxy-7,10-bis[(Z)-4-hydroxy-3-methylbut-2-enyl]-2,2-dimethylpyrano[3,2-b]xanthen-6-one2035475-14-8C28H30O8
Related scaffolds
Same ring framework with different atoms or bond orders
O=C1C=CC2C(=O)C3=Cc4ccccc4CC3CC2C163 chemicals
O=C1c2ccccc2C(=O)c2cc3c(cc21)CCCC313 chemicals
O=C1c2ccccc2C(=O)c2cc3ccccc3cc2111 chemicals
O=C1C=CC2C(=O)c3cc4ccccc4cc3CC2C16 chemicals
O=c1c2ccccc2oc2cc3c(cc12)CCCO34 chemicals
O=c1c2ccccc2oc2nc3n(c(=O)c12)CCCS33 chemicals
O=C1c2cc3ccccc3cc2C(=O)C2C(=O)C=CCC123 chemicals
C=C1c2ccccc2C=C2C(=O)C3C=CC(=O)CC3CC123 chemicals
O=C1CCCc2cc3c(cc21)C(=O)c1ccccc1C3=O2 chemicals![Scaffold O=c1[nH]cnc2c1NC1CC3O[PH](=O)OCC3OC1N2](/scaffold/JGCXBWNZYNTBBR-UHFFFAOYSA-N/structure.svg)
O=c1[nH]cnc2c1NC1CC3O[PH](=O)OCC3OC1N22 chemicals
O=C1c2ccccc2C(=O)c2cc3c(=O)ccoc3cc212 chemicals
c1cnc2c(c1)Nc1nc3ccccc3nc1S21 chemical