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Murcko scaffold

Ring system with 4 rings and 20 atoms

25 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
20
Chemicals
25
With full pages
6
Scaffold SMILES

O=C1C=CC2C(=O)c3cc4ccccc4cc3CC2C1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C1C=CC2C(=O)c3cc4ccccc4cc3CC2C1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 25 of 25 chemicals

Cetocycline chemical structure, C22H21NO7, CAS 29144-42-1
Cetocycline
CAS 29144-42-1C22H21NO7
Cetocycline hydrochloride chemical structure, C22H22ClNO7, CAS 56433-46-6
Cetocycline hydrochloride
CAS 56433-46-6C22H22ClNO7
Bms-192548 chemical structure, C21H18O9, CAS 170663-42-0
Bms-192548
CAS 170663-42-0C21H18O9
Hypomycetin chemical structure, C26H26O10, CAS 178885-61-5
Hypomycetin
CAS 178885-61-5C26H26O10
Anhydrotetracycline chemical structure, C22H22N2O7, CAS 1665-56-1
Anhydrotetracycline
CAS 1665-56-1C22H22N2O7
4-Epianhydrotetracycline chemical structure, C22H22N2O7, CAS 7518-17-4
4-Epianhydrotetracycline
CAS 7518-17-4C22H22N2O7
4-(Dimethylamino)-1,11,12a-trihydroxy-6-methyl-3,12-dioxo-3,4,4a,5,12,12a-hexahydrotetracene-2-carboxamide--hydrogen chloride (1/1) chemical structure, C22H23ClN2O6, CAS 101812-44-6
4-(Dimethylamino)-1,11,12a-trihydroxy-6-methyl-3,12-dioxo-3,4,4a,5,12,12a-hexahydrotetracene-2-carboxamide--hydrogen chloride (1/1)
CAS 101812-44-6C22H23ClN2O6
4-Epianhydrotetracycline hydrochloride chemical structure, C22H23ClN2O7, CAS 4465-65-0
4-Epianhydrotetracycline hydrochloride
CAS 4465-65-0C22H23ClN2O7
Anthrotainin chemical structure, C20H17NO9, CAS 148084-40-6
Anthrotainin
CAS 148084-40-6C20H17NO9
Anhydrochlortetracycline chemical structure, C22H21ClN2O7, CAS 4497-08-9
Anhydrochlortetracycline
CAS 4497-08-9C22H21ClN2O7
4-Epianhydrochlortetracycline chemical structure, C22H21ClN2O7, CAS 81163-11-3
4-Epianhydrochlortetracycline
CAS 81163-11-3C22H21ClN2O7
Anhydro-6-demethyltetracycline chemical structure, C21H20N2O7, CAS 4496-85-9
Anhydro-6-demethyltetracycline
CAS 4496-85-9C21H20N2O7
Anhydrotetracycline hydrochloride chemical structure, C22H23ClN2O7, CAS 13803-65-1
Anhydrotetracycline hydrochloride
CAS 13803-65-1C22H23ClN2O7
Anhydro chlortetracycline hydrochloride chemical structure, C22H22Cl2N2O7, CAS 65490-24-6
Anhydro chlortetracycline hydrochloride
CAS 65490-24-6C22H22Cl2N2O7
4-Epianhydrochlortetracycline hydrochloride chemical structure, C22H22Cl2N2O7, CAS 158018-53-2
4-Epianhydrochlortetracycline hydrochloride
CAS 158018-53-2C22H22Cl2N2O7
4-Amino-7-chloro-1,10,11,12a-tetrahydroxy-3,12-dioxo-3,4,4a,5,12,12a-hexahydrotetracene-2-carboxamide chemical structure, C19H15ClN2O7, CAS 13977-41-8
4-Amino-7-chloro-1,10,11,12a-tetrahydroxy-3,12-dioxo-3,4,4a,5,12,12a-hexahydrotetracene-2-carboxamide
CAS 13977-41-8C19H15ClN2O7
Demeclocycline EP impurity G chemical structure, C21H19ClN2O7, CAS 22688-73-9
Demeclocycline EP impurity G
CAS 22688-73-9C21H19ClN2O7
Omadacycline 5,6-dehydro impurity chemical structure, C29H38N4O7, CAS 2272886-35-6
Omadacycline 5,6-dehydro impurity
CAS 2272886-35-6C29H38N4O7
Previridicatumtoxin chemical structure, C30H33NO10, CAS 1379585-81-5
Previridicatumtoxin
CAS 1379585-81-5C30H33NO10
Minocycline EP impurity H chemical structure, C23H25N3O7, CAS 19119-14-3
Minocycline EP impurity H
CAS 19119-14-3C23H25N3O7
Anhydrooxytetracycline chemical structure, C22H22N2O8, CAS 4660-26-8
Anhydrooxytetracycline
CAS 4660-26-8C22H22N2O8
5,6-Dehydro-tigecycline chemical structure, C29H37N5O8, CAS 1633815-62-9
5,6-Dehydro-tigecycline
CAS 1633815-62-9C29H37N5O8
2-Naphthacenecarbonitrile, 1,4,4a,5,12,12a-hexahydro-3,10,12a-trihydroxy-11-methoxy-6-methyl-1,12-dioxo-, (4aS-cis)- chemical structure, C21H19NO7, CAS 61695-17-8
2-Naphthacenecarbonitrile, 1,4,4a,5,12,12a-hexahydro-3,10,12a-trihydroxy-11-methoxy-6-methyl-1,12-dioxo-, (4aS-cis)-
CAS 61695-17-8C21H19NO7
(4S,4aR,5R,12aS)-4-(Dimethylamino)-3,5,10,11,12a-pentahydroxy-6-methyl-1,12-dioxo-1,4,4a,5,12,12a-hexahydrotetracene-2-carboxamide hydrochloride chemical structure, C22H23ClN2O8, CAS 51596-09-9
(4S,4aR,5R,12aS)-4-(Dimethylamino)-3,5,10,11,12a-pentahydroxy-6-methyl-1,12-dioxo-1,4,4a,5,12,12a-hexahydrotetracene-2-carboxamide hydrochloride
CAS 51596-09-9C22H23ClN2O8