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Murcko scaffold

1-(Phenylsulfonyl)piperidin-4-one scaffold

43 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
16
Chemicals
43
With full pages
4
Scaffold SMILES

O=C1CCN(S(=O)(=O)c2ccccc2)CC1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 1-(Phenylsulfonyl)piperidin-4-one page
Murcko scaffold O=C1CCN(S(=O)(=O)c2ccccc2)CC1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 43 of 43 chemicals

1-Tosylpiperidin-4-one chemical structure, C12H15NO3S, CAS 33439-27-9
1-Tosylpiperidin-4-one
CAS 33439-27-9C12H15NO3S
2-Methyl-1-tosylpiperidin-4-one chemical structure, C13H17NO3S, CAS 13729-78-7
2-Methyl-1-tosylpiperidin-4-one
CAS 13729-78-7C13H17NO3S
1-[(4-Chlorophenyl)sulfonyl]tetrahydro-4(1H)-pyridinone chemical structure, C11H12ClNO3S, CAS 156634-92-3
1-[(4-Chlorophenyl)sulfonyl]tetrahydro-4(1H)-pyridinone
CAS 156634-92-3C11H12ClNO3S
3-Methyl-1-tosylpiperidin-4-one chemical structure, C13H17NO3S, CAS 13729-79-8
3-Methyl-1-tosylpiperidin-4-one
CAS 13729-79-8C13H17NO3S
1-((2-Nitrophenyl)sulfonyl)-4-piperidinone chemical structure, C11H12N2O5S, CAS 267666-09-1
1-((2-Nitrophenyl)sulfonyl)-4-piperidinone
CAS 267666-09-1C11H12N2O5S
3-Bromo-1-tosylpiperidin-4-one chemical structure, C12H14BrNO3S, CAS 171009-41-9
3-Bromo-1-tosylpiperidin-4-one
CAS 171009-41-9C12H14BrNO3S
1-(Phenylsulfonyl)piperidin-4-one chemical structure, C11H13NO3S, CAS 34259-86-4
1-(Phenylsulfonyl)piperidin-4-one
CAS 34259-86-4C11H13NO3S
1-(3,4-Dichlorobenzenesulfonyl)piperidin-4-one chemical structure, C11H11Cl2NO3S, CAS 871216-74-9
1-(3,4-Dichlorobenzenesulfonyl)piperidin-4-one
CAS 871216-74-9C11H11Cl2NO3S
1-(4-Fluoro-benzenesulfonyl)-piperidin-4-one chemical structure, C11H12FNO3S, CAS 216983-39-0
1-(4-Fluoro-benzenesulfonyl)-piperidin-4-one
CAS 216983-39-0C11H12FNO3S
Ethyl 4-oxo-1-tosylpiperidine-3-carboxylate chemical structure, C15H19NO5S, CAS 95034-88-1
Ethyl 4-oxo-1-tosylpiperidine-3-carboxylate
CAS 95034-88-1C15H19NO5S
1-[(4-Nitrophenyl)sulfonyl]tetrahydro-4(1H)-pyridinone chemical structure, C11H12N2O5S, CAS 924869-20-5
1-[(4-Nitrophenyl)sulfonyl]tetrahydro-4(1H)-pyridinone
CAS 924869-20-5C11H12N2O5S
1-(3-Chloro-benzenesulfonyl)-piperidin-4-one chemical structure, C11H12ClNO3S, CAS 1152527-56-4
1-(3-Chloro-benzenesulfonyl)-piperidin-4-one
CAS 1152527-56-4C11H12ClNO3S
1-(4-Methoxybenzenesulfonyl)piperidin-4-one chemical structure, C12H15NO4S, CAS 196085-08-2
1-(4-Methoxybenzenesulfonyl)piperidin-4-one
CAS 196085-08-2C12H15NO4S
1-((4-Bromophenyl)sulfonyl)piperidin-4-one chemical structure, C11H12BrNO3S, CAS 929000-54-4
1-((4-Bromophenyl)sulfonyl)piperidin-4-one
CAS 929000-54-4C11H12BrNO3S
1-[(3,4-Dimethylphenyl)sulfonyl]piperidin-4-one chemical structure, C13H17NO3S, CAS 1018302-24-3
1-[(3,4-Dimethylphenyl)sulfonyl]piperidin-4-one
CAS 1018302-24-3C13H17NO3S
1-[(2,4-Dimethylphenyl)sulfonyl]piperidin-4-one chemical structure, C13H17NO3S, CAS 1018261-39-6
1-[(2,4-Dimethylphenyl)sulfonyl]piperidin-4-one
CAS 1018261-39-6C13H17NO3S
1-[(2,5-Dimethylphenyl)sulfonyl]piperidin-4-one chemical structure, C13H17NO3S, CAS 1018581-06-0
1-[(2,5-Dimethylphenyl)sulfonyl]piperidin-4-one
CAS 1018581-06-0C13H17NO3S
1-[(4-Ethylphenyl)sulfonyl]piperidin-4-one chemical structure, C13H17NO3S, CAS 1018524-26-9
1-[(4-Ethylphenyl)sulfonyl]piperidin-4-one
CAS 1018524-26-9C13H17NO3S
1-[(4-Isopropylphenyl)sulfonyl]piperidin-4-one chemical structure, C14H19NO3S, CAS 1018261-42-1
1-[(4-Isopropylphenyl)sulfonyl]piperidin-4-one
CAS 1018261-42-1C14H19NO3S
1-(Mesitylsulfonyl)piperidin-4-one chemical structure, C14H19NO3S, CAS 1018581-09-3
1-(Mesitylsulfonyl)piperidin-4-one
CAS 1018581-09-3C14H19NO3S
N-{4-[(4-Oxopiperidin-1-yl)sulfonyl]phenyl}acetamide chemical structure, C13H16N2O4S, CAS 145729-15-3
N-{4-[(4-Oxopiperidin-1-yl)sulfonyl]phenyl}acetamide
CAS 145729-15-3C13H16N2O4S
1-[(4-tert-Butylphenyl)sulfonyl]piperidin-4-one chemical structure, C15H21NO3S, CAS 1018302-46-9
1-[(4-tert-Butylphenyl)sulfonyl]piperidin-4-one
CAS 1018302-46-9C15H21NO3S
1-(4-Bromo-2-chlorobenzenesulfonyl)piperidin-4-one chemical structure, C11H11BrClNO3S, CAS 1152584-39-8
1-(4-Bromo-2-chlorobenzenesulfonyl)piperidin-4-one
CAS 1152584-39-8C11H11BrClNO3S
1-(2-Chlorobenzenesulfonyl)piperidin-4-one chemical structure, C11H12ClNO3S, CAS 911644-00-3
1-(2-Chlorobenzenesulfonyl)piperidin-4-one
CAS 911644-00-3C11H12ClNO3S