Murcko scaffold
1-(Phenylsulfonyl)piperidine scaffold
2,210 chemicals on CompoundList share this ring system.
- Rings
- 2
- Scaffold atoms
- 15
- Chemicals
- 2,210
- With full pages
- 266
Scaffold SMILES
O=S(=O)(c1ccccc1)N1CCCCC1
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 48 of 2,210 chemicals
1-(4-Isothiocyanatophenylsulfonyl)piperidine
CAS 7356-55-0C12H14N2O2S2
rel-2-Chloro-5-(((3R,5S)-3,5-dimethyl-1-piperidinyl)sulfonyl)benzoic acid
CAS 37087-94-8C14H18ClNO4S
Piperidine, 1-(p-tolylsulfonyl)-
CAS 4703-22-4C12H17NO2S
1-(Phenylsulfonyl)piperidine
CAS 5033-23-8C11H15NO2S
N-(4-(1-Piperidinylsulfonyl)phenyl)acetamide
CAS 5702-82-9C13H18N2O3S
1-((4-Bromophenyl)sulfonyl)piperidine
CAS 834-66-2C11H14BrNO2S
4-(Piperidine-1-sulfonyl)aniline
CAS 6336-68-1C11H16N2O2S
1-((p-Methoxyphenyl)sulfonyl)piperidine
CAS 35088-89-2C12H17NO3S
1-(4-Ethoxyphenyl)sulfonylpiperidine
CAS 32176-33-3C13H19NO3S
1-(Phenylsulfonyl)piperidine-4-carboxamide
CAS 304668-32-4C12H16N2O3S
1-(Phenylsulfonyl)-4,4-piperidinedicarboxylic acid
CAS 225517-21-5C13H15NO6S
Methyl 1-(phenylsulfonyl)-4-piperidinecarboxylate
CAS 311794-15-7C13H17NO4S
Ethyl 1-(phenylsulfonyl)piperidine-4-carboxylate
CAS 111627-26-0C14H19NO4S
1-(Phenylsulfonyl)-4-piperidinecarboxylic acid hydrazide
CAS 312534-14-8C12H17N3O3S
1-(3-Nitrophenylsulfonyl)piperidine
CAS 91619-31-7C11H14N2O4S
1-(4-Chlorophenylsulfonyl)-4-methylpiperidine
CAS 197512-74-6C12H16ClNO2S
4-(Piperidine-1-sulfonyl)benzene-1-sulfonamide
CAS 1150-21-6C11H16N2O4S2
![1-[(4-Fluorophenyl)sulfonyl]-4-piperidinecarboxamide chemical structure, C12H15FN2O3S, CAS 309279-85-4](/s/UBCOXBOQTVXGEK-UHFFFAOYSA-N.svg)
1-[(4-Fluorophenyl)sulfonyl]-4-piperidinecarboxamide
CAS 309279-85-4C12H15FN2O3S
![1-[(4-Methylphenyl)sulfonyl]-4-piperidinecarboxamide chemical structure, C13H18N2O3S, CAS 309279-87-6](/s/MKLKAEFDIVQLTD-UHFFFAOYSA-N.svg)
1-[(4-Methylphenyl)sulfonyl]-4-piperidinecarboxamide
CAS 309279-87-6C13H18N2O3S
1-(4-Chloro-3-methoxy-benzenesulfonyl)-4-methyl-piperidine
CAS 409357-29-5C13H18ClNO3S
![1-[(4-Chlorophenyl)sulfonyl]piperidine-4-carbohydrazide chemical structure, C12H16ClN3O3S, CAS 332400-85-8](/s/OFPWIKXAQKSKPL-UHFFFAOYSA-N.svg)
1-[(4-Chlorophenyl)sulfonyl]piperidine-4-carbohydrazide
CAS 332400-85-8C12H16ClN3O3S
![2-[4-(2-Methyl-piperidine-1-sulfonyl)-phenyl]-ethylamine chemical structure, C14H22N2O2S, CAS 498530-53-3](/s/AKNMFKYHSBWRLH-UHFFFAOYSA-N.svg)
2-[4-(2-Methyl-piperidine-1-sulfonyl)-phenyl]-ethylamine
CAS 498530-53-3C14H22N2O2S
![2-Ethyl-1-[(2-nitrophenyl)sulfonyl]piperidine chemical structure, C13H18N2O4S, CAS 331256-11-2](/s/FTPHIBITRUCWJT-UHFFFAOYSA-N.svg)
2-Ethyl-1-[(2-nitrophenyl)sulfonyl]piperidine
CAS 331256-11-2C13H18N2O4S
![Piperidine, 1-[(2,5-dichlorophenyl)sulfonyl]- chemical structure, C11H13Cl2NO2S, CAS 88522-24-1](/s/BXSVOWIFQVJUKH-UHFFFAOYSA-N.svg)
Piperidine, 1-[(2,5-dichlorophenyl)sulfonyl]-
CAS 88522-24-1C11H13Cl2NO2S
- 1-(4-Chloro-3-ethoxyphenyl)sulfonylpiperidine723741-37-5C13H18ClNO3S
- 1-[(2,5-Diethoxyphenyl)sulfonyl]-2-methylpiperidine325811-04-9C16H25NO4S
- (3R)-3-Methyl-1-((4-methylphenyl)sulfonyl)piperidine37675-22-2C13H19NO2S
- (2S)-2-Methyl-1-[(4-methylphenyl)sulfonyl]piperidine3197-43-1C13H19NO2S
- 1-{[4-(Acetylamino)phenyl]sulfonyl}piperidine-4-carboxamide304668-29-9C14H19N3O4S
- 4-Fluoro-3-(1-piperidinylsulfonyl)benzoic acid311785-51-0C12H14FNO4S
- Methyl 1-[(4-methylphenyl)sulfonyl]-4-piperidinecarboxylate311794-12-4C14H19NO4S
- Ethyl 1-((4-chlorophenyl)sulfonyl)piperidine-4-carboxylate313685-03-9C14H18ClNO4S
- 2-Hydroxy-5-(piperidin-1-ylsulfonyl)benzoic acid91642-62-5C12H15NO5S
- Ethyl 1-(4-fluorophenyl)sulfonylpiperidine-4-carboxylate5352-24-9C14H18FNO4S
- 4-Methyl-1-{[3-(trifluoromethyl)phenyl]sulfonyl}piperidine613657-79-7C13H16F3NO2S
- 1-(3-Chloro-4-fluorophenyl)sulfonylpiperidine612043-25-1C11H13ClFNO2S
- 1-((4-Chloro-3-(trifluoromethyl)phenyl)sulfonyl)piperidine612041-95-9C12H13ClF3NO2S
- {[2-(Trifluoromethyl)phenyl]sulfonyl}piperidine612042-59-8C12H14F3NO2S
- 2-(Piperidine-1-sulfonyl)benzonitrile440353-70-8C12H14N2O2S
- 1-[(2,4,5-Trichlorophenyl)sulfonyl]piperidine92847-52-4C11H12Cl3NO2S
- 1-[(4-Methoxy-2,3,5-trimethylphenyl)sulfonyl]piperidine-4-carboxamide691380-74-2C16H24N2O4S
- 1-((4-Methoxy-2,3-dimethylphenyl)sulfonyl)piperidine-4-carboxamide691380-75-3C15H22N2O4S
- (2E)-4-Oxo-4-{[4-(piperidin-1-ylsulfonyl)phenyl]amino}but-2-enoic acid315671-16-0C15H18N2O5S
- RefChem:31392556099-73-1C13H17NO4S
- 1-[(4-Ethoxyphenyl)sulfonyl]-4-piperidinecarboxamide380459-27-8C14H20N2O4S
- 1-[(4-Chloro-3-methoxyphenyl)sulfonyl]-4-piperidinecarboxamide681853-42-9C13H17ClN2O4S
- 1-(2-Methoxy-5-methylphenyl)sulfonylpiperidine-4-carboxamide681853-43-0C14H20N2O4S
- 1-(5-Chloro-2-methoxybenzenesulfonyl)piperidine-4-carboxamide681853-44-1C13H17ClN2O4S
Related scaffolds
Same ring framework with different atoms or bond orders
c1ccc(Cc2ccccc2)cc1952 chemicals
c1ccc(Oc2ccccc2)cc1933 chemicals
O=C(c1ccccc1)c1ccccc1537 chemicals
c1ccc(Nc2ccccc2)cc1395 chemicals
c1ccc(CN2CCCCC2)cc1283 chemicals
c1ccc(CN2CCNCC2)cc1267 chemicals
c1ccc(Oc2ccccn2)cc1238 chemicals
c1ccc(Sc2ccccc2)cc1195 chemicals
O=S(=O)(c1ccccc1)N1CCNCC1195 chemicals
c1ccc(OC2CCCCO2)cc1164 chemicals
O=C(c1ccccc1)N1CCCCC1164 chemicals
O=S(=O)(c1ccccc1)N1CCOCC1148 chemicals