Murcko scaffold
3-Cyclopropyl-1H-pyrazolo[3,4-b]pyridine scaffold
38 chemicals on CompoundList share this ring system.
- Rings
- 3
- Scaffold atoms
- 12
- Chemicals
- 38
- With full pages
- 2
Scaffold SMILES
c1cnc2[nH]nc(C3CC3)c2c1
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
![Murcko scaffold c1cnc2[nH]nc(C3CC3)c2c1](/scaffold/RIIYEVCNRJZSTG-UHFFFAOYSA-N/structure.svg)
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 38 of 38 chemicals
![(3-Cyclopropyl-1H-pyrazolo[3,4-b]pyridin-1-yl)acetic acid chemical structure, C11H11N3O2, CAS 937605-64-6](/s/XDJRMHRPJVGPIW-UHFFFAOYSA-N.svg)
(3-Cyclopropyl-1H-pyrazolo[3,4-b]pyridin-1-yl)acetic acid
CAS 937605-64-6C11H11N3O2
![(3-Cyclopropyl-4,6-dimethyl-1H-pyrazolo[3,4-b]pyridin-1-yl)acetic acid chemical structure, C13H15N3O2, CAS 937605-66-8](/s/KHRQTNIJKWGROM-UHFFFAOYSA-N.svg)
(3-Cyclopropyl-4,6-dimethyl-1H-pyrazolo[3,4-b]pyridin-1-yl)acetic acid
CAS 937605-66-8C13H15N3O2
![(3-Cyclopropyl-5-methyl-1H-pyrazolo[3,4-b]pyridin-1-yl)acetic acid chemical structure, C12H13N3O2, CAS 937605-70-4](/s/UEKXNTDSZUISKK-UHFFFAOYSA-N.svg)
(3-Cyclopropyl-5-methyl-1H-pyrazolo[3,4-b]pyridin-1-yl)acetic acid
CAS 937605-70-4C12H13N3O2
![2-(3-Cyclopropyl-6-methyl-4-(trifluoromethyl)-1H-pyrazolo[3,4-b]pyridin-1-yl)acetic acid chemical structure, C13H12F3N3O2, CAS 937606-00-3](/s/PDEKKKQBJUJOQT-UHFFFAOYSA-N.svg)
2-(3-Cyclopropyl-6-methyl-4-(trifluoromethyl)-1H-pyrazolo[3,4-b]pyridin-1-yl)acetic acid
CAS 937606-00-3C13H12F3N3O2
![2-(3-Cyclopropyl-4-(difluoromethyl)-6-methyl-1H-pyrazolo[3,4-b]pyridin-1-yl)acetic acid chemical structure, C13H13F2N3O2, CAS 937607-22-2](/s/JLWORTBHQDPDEQ-UHFFFAOYSA-N.svg)
2-(3-Cyclopropyl-4-(difluoromethyl)-6-methyl-1H-pyrazolo[3,4-b]pyridin-1-yl)acetic acid
CAS 937607-22-2C13H13F2N3O2
![Ethyl 2-(3-cyclopropyl-4-(difluoromethyl)-6-methyl-1H-pyrazolo[3,4-b]pyridin-1-yl)acetate chemical structure, C15H17F2N3O2, CAS 1018050-81-1](/s/DLOKRUMEALBWRA-UHFFFAOYSA-N.svg)
Ethyl 2-(3-cyclopropyl-4-(difluoromethyl)-6-methyl-1H-pyrazolo[3,4-b]pyridin-1-yl)acetate
CAS 1018050-81-1C15H17F2N3O2
![Ethyl 2-(3-cyclopropyl-6-methyl-4-(trifluoromethyl)-1H-pyrazolo[3,4-b]pyridin-1-yl)acetate chemical structure, C15H16F3N3O2, CAS 1018141-86-0](/s/PNBOUPPYLNNMKQ-UHFFFAOYSA-N.svg)
Ethyl 2-(3-cyclopropyl-6-methyl-4-(trifluoromethyl)-1H-pyrazolo[3,4-b]pyridin-1-yl)acetate
CAS 1018141-86-0C15H16F3N3O2
![2-(3-Cyclopropyl-4-(methoxycarbonyl)-6-methyl-1H-pyrazolo[3,4-b]pyridin-1-yl)acetic acid chemical structure, C14H15N3O4, CAS 1018141-95-1](/s/YYRCOJWETHBGFO-UHFFFAOYSA-N.svg)
2-(3-Cyclopropyl-4-(methoxycarbonyl)-6-methyl-1H-pyrazolo[3,4-b]pyridin-1-yl)acetic acid
CAS 1018141-95-1C14H15N3O4
![Methyl 3-cyclopropyl-1-(2-(isopropylamino)-2-oxoethyl)-6-methyl-1H-pyrazolo[3,4-b]pyridine-4-carboxylate chemical structure, C17H22N4O3, CAS 1018141-99-5](/s/SFLPQSIGWAKCTI-UHFFFAOYSA-N.svg)
Methyl 3-cyclopropyl-1-(2-(isopropylamino)-2-oxoethyl)-6-methyl-1H-pyrazolo[3,4-b]pyridine-4-carboxylate
CAS 1018141-99-5C17H22N4O3
![3-Cyclopropyl-1-(2-(isopropylamino)-2-oxoethyl)-6-methyl-1H-pyrazolo[3,4-b]pyridine-4-carboxylic acid chemical structure, C16H20N4O3, CAS 1018052-62-4](/s/FDTLMGDLQFBPDP-UHFFFAOYSA-N.svg)
3-Cyclopropyl-1-(2-(isopropylamino)-2-oxoethyl)-6-methyl-1H-pyrazolo[3,4-b]pyridine-4-carboxylic acid
CAS 1018052-62-4C16H20N4O3
![Methyl 3-cyclopropyl-1-{2-[(2-methoxyethyl)amino]-2-oxoethyl}-6-methyl-1H-pyrazolo[3,4-b]pyridine-4-carboxylate chemical structure, C17H22N4O4, CAS 1018142-77-2](/s/NZEHEONQJQVVJZ-UHFFFAOYSA-N.svg)
Methyl 3-cyclopropyl-1-{2-[(2-methoxyethyl)amino]-2-oxoethyl}-6-methyl-1H-pyrazolo[3,4-b]pyridine-4-carboxylate
CAS 1018142-77-2C17H22N4O4
![3-Cyclopropyl-1-(2-((2-methoxyethyl)amino)-2-oxoethyl)-6-methyl-1H-pyrazolo[3,4-b]pyridine-4-carboxylic acid chemical structure, C16H20N4O4, CAS 1018142-80-7](/s/SXYDLFZRZKRIQW-UHFFFAOYSA-N.svg)
3-Cyclopropyl-1-(2-((2-methoxyethyl)amino)-2-oxoethyl)-6-methyl-1H-pyrazolo[3,4-b]pyridine-4-carboxylic acid
CAS 1018142-80-7C16H20N4O4
![2-(3-Cyclopropyl-6-ethyl-4-(trifluoromethyl)-1H-pyrazolo[3,4-b]pyridin-1-yl)acetic acid chemical structure, C14H14F3N3O2, CAS 1018125-49-9](/s/LQYSIDBOBXQTPN-UHFFFAOYSA-N.svg)
2-(3-Cyclopropyl-6-ethyl-4-(trifluoromethyl)-1H-pyrazolo[3,4-b]pyridin-1-yl)acetic acid
CAS 1018125-49-9C14H14F3N3O2
![2-(3-Cyclopropyl-6-isopropyl-4-(trifluoromethyl)-1H-pyrazolo[3,4-b]pyridin-1-yl)acetic acid chemical structure, C15H16F3N3O2, CAS 1018144-00-7](/s/HZAYSKLDMAVKLR-UHFFFAOYSA-N.svg)
2-(3-Cyclopropyl-6-isopropyl-4-(trifluoromethyl)-1H-pyrazolo[3,4-b]pyridin-1-yl)acetic acid
CAS 1018144-00-7C15H16F3N3O2
![Ethyl 2-(3-cyclopropyl-6-ethyl-4-(trifluoromethyl)-1H-pyrazolo[3,4-b]pyridin-1-yl)acetate chemical structure, C16H18F3N3O2, CAS 1011378-45-2](/s/LZYJPOLNAKTNOB-UHFFFAOYSA-N.svg)
Ethyl 2-(3-cyclopropyl-6-ethyl-4-(trifluoromethyl)-1H-pyrazolo[3,4-b]pyridin-1-yl)acetate
CAS 1011378-45-2C16H18F3N3O2
![3-Cyclopropyl-1,6-diethyl-1H-pyrazolo[3,4-b]pyridine-4-carboxylic acid chemical structure, C14H17N3O2, CAS 1119429-08-1](/s/DMJNUAXNPYFJIG-UHFFFAOYSA-N.svg)
3-Cyclopropyl-1,6-diethyl-1H-pyrazolo[3,4-b]pyridine-4-carboxylic acid
CAS 1119429-08-1C14H17N3O2
3-Cyclopropyl-6-ethyl-1-methyl-4-(trifluoromethyl)-1H-pyrazolo(3,4-b)pyridine
CAS 1011397-33-3C13H14F3N3
![3-(2,2-Difluorocyclopropyl)-1H-pyrazolo[3,4-b]pyridin-5-amine chemical structure, C9H8F2N4, CAS 1186609-93-7](/s/CZUHLHOULVBWLN-UHFFFAOYSA-N.svg)
3-(2,2-Difluorocyclopropyl)-1H-pyrazolo[3,4-b]pyridin-5-amine
CAS 1186609-93-7C9H8F2N4
![3-Cyclopropyl-1H-pyrazolo[3,4-b]pyridin-5-amine chemical structure, C9H10N4, CAS 1186608-75-2](/s/XLUCOJFGPLYLKB-UHFFFAOYSA-N.svg)
3-Cyclopropyl-1H-pyrazolo[3,4-b]pyridin-5-amine
CAS 1186608-75-2C9H10N4
![3-Cyclopropyl-5-nitro-1H-pyrazolo[3,4-b]pyridine chemical structure, C9H8N4O2, CAS 1186608-74-1](/s/MPPCYRLHEBJLSG-UHFFFAOYSA-N.svg)
3-Cyclopropyl-5-nitro-1H-pyrazolo[3,4-b]pyridine
CAS 1186608-74-1C9H8N4O2
![(3-Cyclopropyl-1,4-dimethyl-1H-pyrazolo[3,4-b]pyridin-6-yloxy)acetic acid chemical structure, C13H15N3O3, CAS 1312949-36-2](/s/KFFXDDXSMBVGNP-UHFFFAOYSA-N.svg)
(3-Cyclopropyl-1,4-dimethyl-1H-pyrazolo[3,4-b]pyridin-6-yloxy)acetic acid
CAS 1312949-36-2C13H15N3O3
![(3-Cyclopropyl-1-methyl-1H-pyrazolo[3,4-b]pyridin-6-yloxy)-acetic acid chemical structure, C12H13N3O3, CAS 1312949-43-1](/s/AHTWVKQQYUFNAK-UHFFFAOYSA-N.svg)
(3-Cyclopropyl-1-methyl-1H-pyrazolo[3,4-b]pyridin-6-yloxy)-acetic acid
CAS 1312949-43-1C12H13N3O3
![(3-Cyclopropyl-1,5-dimethyl-1H-pyrazolo[3,4-b]pyridin-6-yloxy)acetic acid chemical structure, C13H15N3O3, CAS 1312949-38-4](/s/IIMRNQAKTPFWOW-UHFFFAOYSA-N.svg)
(3-Cyclopropyl-1,5-dimethyl-1H-pyrazolo[3,4-b]pyridin-6-yloxy)acetic acid
CAS 1312949-38-4C13H15N3O3
![5-Bromo-3-cyclopropyl-1-[[2-(trimethylsilyl)ethoxy]methyl]-1H-pyrazolo[3,4-b]pyridine chemical structure, C15H22BrN3OSi, CAS 1421685-10-0](/s/VZVNSJAWJAXJHX-UHFFFAOYSA-N.svg)
5-Bromo-3-cyclopropyl-1-[[2-(trimethylsilyl)ethoxy]methyl]-1H-pyrazolo[3,4-b]pyridine
CAS 1421685-10-0C15H22BrN3OSi
- 3-Cyclopropyl-1H-pyrazolo[3,4-b]pyridine-5-carboxylic acid1256811-84-3C10H9N3O2
- 3-Cyclopropyl-1-methyl-1H-pyrazolo[3,4-b]pyridine-4-carboxylic acid1781983-41-2C11H11N3O2
- 5-Bromo-3-cyclopropyl-1-methyl-1H-pyrazolo[3,4-b]pyridine1780327-06-1C10H10BrN3
- 5-Bromo-3-cyclopropyl-1H-pyrazolo[3,4-b]pyridine1211537-03-9C9H8BrN3
- 6-Chloro-3-cyclopropyl-1H-pyrazolo(3,4-b)pyridine1803591-69-6C9H8ClN3
- 3-Cyclopropyl-1-methyl-1H-pyrazolo[3,4-b]pyridine-5-sulfonyl chloride1909310-07-1C10H10ClN3O2S
- 3-Cyclopropyl-1H-pyrazolo[3,4-b]pyridin-5-amine hydrochloride2251053-43-5C9H11ClN4
- 3-Cyclopropyl-1H-pyrazolo[3,4-b]pyridine2386070-77-3C9H9N3
- 3-Cyclopropyl-1-methyl-1H-pyrazolo[3,4-b]pyridine-5-sulfonyl fluoride2138192-68-2C10H10FN3O2S
- Methyl 4-chloro-3-cyclopropyl-1H-pyrazolo[3,4-B]pyridine-6-carboxylate2708278-73-1C11H10ClN3O2
- Methyl 3-cyclopropyl-1H-pyrazolo[3,4-B]pyridine-6-carboxylate2705222-65-5C11H11N3O2
- Sodium 3-cyclopropyl-1-methyl-1H-pyrazolo[3,4-b]pyridine-5-sulfinate2138147-46-1C10H10N3NaO2S
- 3-Cyclopropyl-1-methyl-1H-pyrazolo[3,4-b]pyridine-5-sulfonamide2639426-05-2C10H12N4O2S
- 3-Cyclopropyl-1-[[2-(trimethylsilyl)ethoxy]methyl]-1H-pyrazolo[3,4-b]pyridin-5-ol2795141-56-7C15H23N3O2Si
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