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Murcko scaffold

Ring system with 3 rings and 19 atoms

27 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
19
Chemicals
27
With full pages
9
Scaffold SMILES

O=c1cc(CNc2ccccc2)c2ccccc2o1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=c1cc(CNc2ccccc2)c2ccccc2o1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 27 of 27 chemicals

4-(Anilinomethyl)-3-nitrochromen-2-one chemical structure, C16H12N2O4, CAS 336168-49-1
4-(Anilinomethyl)-3-nitrochromen-2-one
CAS 336168-49-1C16H12N2O4
4-(((4-Ethoxyphenyl)amino)methyl)-7,8-dimethyl-2H-chromen-2-one chemical structure, C20H21NO3, CAS 848740-02-3
4-(((4-Ethoxyphenyl)amino)methyl)-7,8-dimethyl-2H-chromen-2-one
CAS 848740-02-3C20H21NO3
Methyl 2-{[(7-methoxy-2-oxo-2H-chromen-4-yl)methyl]amino}benzoate chemical structure, C19H17NO5, CAS 859142-27-1
Methyl 2-{[(7-methoxy-2-oxo-2H-chromen-4-yl)methyl]amino}benzoate
CAS 859142-27-1C19H17NO5
Methyl 2-{[(6-hydroxy-7-methyl-2-oxochromen-4-yl)methyl]amino}benzoate chemical structure, C19H17NO5, CAS 859142-97-5
Methyl 2-{[(6-hydroxy-7-methyl-2-oxochromen-4-yl)methyl]amino}benzoate
CAS 859142-97-5C19H17NO5
6-Hydroxy-4-{[(3-methoxyphenyl)amino]methyl}-7-methyl-2H-chromen-2-one chemical structure, C18H17NO4, CAS 859859-11-3
6-Hydroxy-4-{[(3-methoxyphenyl)amino]methyl}-7-methyl-2H-chromen-2-one
CAS 859859-11-3C18H17NO4
6-Hydroxy-7-methyl-4-{[(2-methylphenyl)amino]methyl}-2H-chromen-2-one chemical structure, C18H17NO3, CAS 859861-10-2
6-Hydroxy-7-methyl-4-{[(2-methylphenyl)amino]methyl}-2H-chromen-2-one
CAS 859861-10-2C18H17NO3
Methyl 2-{[(6-hydroxy-7-methyl-2-oxo-2H-chromen-4-yl)methyl]amino}-4,5-dimethoxybenzoate chemical structure, C21H21NO7, CAS 859861-39-5
Methyl 2-{[(6-hydroxy-7-methyl-2-oxo-2H-chromen-4-yl)methyl]amino}-4,5-dimethoxybenzoate
CAS 859861-39-5C21H21NO7
N-(4-{[(7-Methoxy-2-oxo-2H-chromen-4-yl)methyl]amino}phenyl)-N-methylacetamide chemical structure, C20H20N2O4, CAS 859859-65-7
N-(4-{[(7-Methoxy-2-oxo-2H-chromen-4-yl)methyl]amino}phenyl)-N-methylacetamide
CAS 859859-65-7C20H20N2O4
7-Methoxy-4-{[(2-methylphenyl)amino]methyl}-2H-chromen-2-one chemical structure, C18H17NO3, CAS 859864-25-8
7-Methoxy-4-{[(2-methylphenyl)amino]methyl}-2H-chromen-2-one
CAS 859864-25-8C18H17NO3
6-Hydroxy-7-methyl-4-({[3-(trifluoromethyl)phenyl]amino}methyl)chromen-2-one chemical structure, C18H14F3NO3, CAS 859866-37-8
6-Hydroxy-7-methyl-4-({[3-(trifluoromethyl)phenyl]amino}methyl)chromen-2-one
CAS 859866-37-8C18H14F3NO3
4-{[(2-Fluorophenyl)amino]methyl}-6-hydroxy-7-methyl-2H-chromen-2-one chemical structure, C17H14FNO3, CAS 859108-08-0
4-{[(2-Fluorophenyl)amino]methyl}-6-hydroxy-7-methyl-2H-chromen-2-one
CAS 859108-08-0C17H14FNO3
Dimethyl 2-(((6-hydroxy-7-methyl-2-oxo-2H-chromen-4-yl)methyl)amino)terephthalate chemical structure, C21H19NO7, CAS 859108-16-0
Dimethyl 2-(((6-hydroxy-7-methyl-2-oxo-2H-chromen-4-yl)methyl)amino)terephthalate
CAS 859108-16-0C21H19NO7
Ethyl 2-{[(7-methoxy-2-oxo-2H-chromen-4-yl)methyl]amino}benzoate chemical structure, C20H19NO5, CAS 859108-43-3
Ethyl 2-{[(7-methoxy-2-oxo-2H-chromen-4-yl)methyl]amino}benzoate
CAS 859108-43-3C20H19NO5
4-{[(2,3-Dimethylphenyl)amino]methyl}-7-methoxy-2H-chromen-2-one chemical structure, C19H19NO3, CAS 859109-71-0
4-{[(2,3-Dimethylphenyl)amino]methyl}-7-methoxy-2H-chromen-2-one
CAS 859109-71-0C19H19NO3
4-{[(3,5-Dimethylphenyl)amino]methyl}-6-hydroxy-7-methyl-2H-chromen-2-one chemical structure, C19H19NO3, CAS 859111-32-3
4-{[(3,5-Dimethylphenyl)amino]methyl}-6-hydroxy-7-methyl-2H-chromen-2-one
CAS 859111-32-3C19H19NO3
Ethyl 2-{[(6-hydroxy-7-methyl-2-oxo-2H-chromen-4-yl)methyl]amino}benzoate chemical structure, C20H19NO5, CAS 859114-17-3
Ethyl 2-{[(6-hydroxy-7-methyl-2-oxo-2H-chromen-4-yl)methyl]amino}benzoate
CAS 859114-17-3C20H19NO5
7-Methoxy-4-{[(3-methoxyphenyl)amino]methyl}-2H-chromen-2-one chemical structure, C18H17NO4, CAS 859129-31-0
7-Methoxy-4-{[(3-methoxyphenyl)amino]methyl}-2H-chromen-2-one
CAS 859129-31-0C18H17NO4
4-{[(2,4-Dimethylphenyl)amino]methyl}-7-methoxy-2H-chromen-2-one chemical structure, C19H19NO3, CAS 859129-35-4
4-{[(2,4-Dimethylphenyl)amino]methyl}-7-methoxy-2H-chromen-2-one
CAS 859129-35-4C19H19NO3
7-Methoxy-4-{[(4-methylphenyl)amino]methyl}-2H-chromen-2-one chemical structure, C18H17NO3, CAS 79344-52-8
7-Methoxy-4-{[(4-methylphenyl)amino]methyl}-2H-chromen-2-one
CAS 79344-52-8C18H17NO3
4-{[(2,3-Dimethylphenyl)amino]methyl}-6-hydroxy-7-methyl-2H-chromen-2-one chemical structure, C19H19NO3, CAS 859129-58-1
4-{[(2,3-Dimethylphenyl)amino]methyl}-6-hydroxy-7-methyl-2H-chromen-2-one
CAS 859129-58-1C19H19NO3
4-(((2-Ethoxyphenyl)amino)methyl)-6-hydroxy-7-methyl-2H-chromen-2-one chemical structure, C19H19NO4, CAS 859112-52-0
4-(((2-Ethoxyphenyl)amino)methyl)-6-hydroxy-7-methyl-2H-chromen-2-one
CAS 859112-52-0C19H19NO4
4-[(3-Methoxyanilino)methyl]-7-methyl-6-propan-2-ylchromen-2-one chemical structure, C21H23NO3, CAS 854027-71-7
4-[(3-Methoxyanilino)methyl]-7-methyl-6-propan-2-ylchromen-2-one
CAS 854027-71-7C21H23NO3
Methyl 2-{[(6,7-dihydroxy-2-oxo-2H-chromen-4-yl)methyl]amino}benzoate chemical structure, C18H15NO6, CAS 859141-94-9
Methyl 2-{[(6,7-dihydroxy-2-oxo-2H-chromen-4-yl)methyl]amino}benzoate
CAS 859141-94-9C18H15NO6
6,7-Dihydroxy-4-{[(2-methylphenyl)amino]methyl}-2H-chromen-2-one chemical structure, C17H15NO4, CAS 859860-91-6
6,7-Dihydroxy-4-{[(2-methylphenyl)amino]methyl}-2H-chromen-2-one
CAS 859860-91-6C17H15NO4