CompoundList
Sign in
Murcko scaffold

Ring system with 3 rings and 20 atoms

14 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
20
Chemicals
14
With full pages
5
Scaffold SMILES

O=C(Cc1ccccc1)N=Nc1c[nH]c2ccccc12

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(Cc1ccccc1)N=Nc1c[nH]c2ccccc12

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 14 of 14 chemicals

N'-(2-Oxo-1,2-dihydro-3H-indol-3-ylidene)-2-phenylacetohydrazide chemical structure, C16H13N3O2, CAS 300805-68-9
N'-(2-Oxo-1,2-dihydro-3H-indol-3-ylidene)-2-phenylacetohydrazide
CAS 300805-68-9C16H13N3O2
2-(4-Methoxyphenyl)-N'-(2-oxo-1,2-dihydro-3H-indol-3-ylidene)acetohydrazide chemical structure, C17H15N3O3, CAS 828252-49-9
2-(4-Methoxyphenyl)-N'-(2-oxo-1,2-dihydro-3H-indol-3-ylidene)acetohydrazide
CAS 828252-49-9C17H15N3O3
Phenyl-acetic acid (5,7-dibromo-2-oxo-1,2-dihydro-indol-3-ylidene)-hydrazide chemical structure, C16H11Br2N3O2, CAS 300567-86-6
Phenyl-acetic acid (5,7-dibromo-2-oxo-1,2-dihydro-indol-3-ylidene)-hydrazide
CAS 300567-86-6C16H11Br2N3O2
Methyl (2-oxo-3-((phenylacetyl)hydrazono)-2,3-dihydro-1H-indol-1-yl)acetate chemical structure, C19H17N3O4, CAS 341975-22-2
Methyl (2-oxo-3-((phenylacetyl)hydrazono)-2,3-dihydro-1H-indol-1-yl)acetate
CAS 341975-22-2C19H17N3O4
2-(2-Chlorophenyl)-N'-(2-oxoindol-3-yl)acetohydrazide chemical structure, C16H12ClN3O2, CAS 1159976-54-1
2-(2-Chlorophenyl)-N'-(2-oxoindol-3-yl)acetohydrazide
CAS 1159976-54-1C16H12ClN3O2
Ethyl ((3Z)-3-{[(4-hydroxy-3-methoxyphenyl)acetyl]hydrazono}-2-oxo-2,3-dihydro-1H-indol-1-yl)acetate chemical structure, C21H21N3O6, CAS 624726-32-5
Ethyl ((3Z)-3-{[(4-hydroxy-3-methoxyphenyl)acetyl]hydrazono}-2-oxo-2,3-dihydro-1H-indol-1-yl)acetate
CAS 624726-32-5C21H21N3O6
ET (3-(((4-CL-Phenyl)acetyl)hydrazono)-2-oxo-2,3-dihydro-1H-indol-1-yl)acetate chemical structure, C20H18ClN3O4, CAS 624726-30-3
ET (3-(((4-CL-Phenyl)acetyl)hydrazono)-2-oxo-2,3-dihydro-1H-indol-1-yl)acetate
CAS 624726-30-3C20H18ClN3O4
N'-[(3Z)-5-Bromo-2-oxo-1,2-dihydro-3H-indol-3-ylidene]-2-(3,4-dimethoxyphenyl)acetohydrazide chemical structure, C18H16BrN3O4, CAS 828251-08-7
N'-[(3Z)-5-Bromo-2-oxo-1,2-dihydro-3H-indol-3-ylidene]-2-(3,4-dimethoxyphenyl)acetohydrazide
CAS 828251-08-7C18H16BrN3O4
(Z)-2-(4-Nitrophenyl)-N'-(2-oxoindolin-3-ylidene)acetohydrazide chemical structure, C16H12N4O4, CAS 95059-95-3
(Z)-2-(4-Nitrophenyl)-N'-(2-oxoindolin-3-ylidene)acetohydrazide
CAS 95059-95-3C16H12N4O4
Benzeneacetic acid, 2-(1-butyl-1,2-dihydro-5-methyl-2-oxo-3H-indol-3-ylidene)hydrazide chemical structure, C21H23N3O2, CAS 609781-35-3
Benzeneacetic acid, 2-(1-butyl-1,2-dihydro-5-methyl-2-oxo-3H-indol-3-ylidene)hydrazide
CAS 609781-35-3C21H23N3O2
N-(Aza(5-iodo-2-oxoindolin-3-ylidene)methyl)-2-(2-chlorophenyl)ethanamide chemical structure, C16H11ClIN3O2, CAS 1024534-81-3
N-(Aza(5-iodo-2-oxoindolin-3-ylidene)methyl)-2-(2-chlorophenyl)ethanamide
CAS 1024534-81-3C16H11ClIN3O2
2-(4-CL-PH)-N'-(5-Nitro-2-oxo-1,2-dihydro-3H-indol-3-ylidene)acetohydrazide chemical structure, C16H11ClN4O4, CAS 328902-38-1
2-(4-CL-PH)-N'-(5-Nitro-2-oxo-1,2-dihydro-3H-indol-3-ylidene)acetohydrazide
CAS 328902-38-1C16H11ClN4O4
2-(3-Chlorophenyl)-N'-(2-oxo-1,2-dihydro-3H-indol-3-yliden)acetohydrazide chemical structure, C16H12ClN3O2, CAS 828251-06-5
2-(3-Chlorophenyl)-N'-(2-oxo-1,2-dihydro-3H-indol-3-yliden)acetohydrazide
CAS 828251-06-5C16H12ClN3O2
5-Bromo-3-(2-(3-chlorophenyl)acetylhydrazidyl)-2-oxoindoline chemical structure, C16H11BrClN3O2, CAS 828251-07-6
5-Bromo-3-(2-(3-chlorophenyl)acetylhydrazidyl)-2-oxoindoline
CAS 828251-07-6C16H11BrClN3O2