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Murcko scaffold

Ring system with 2 rings and 16 atoms

13 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
16
Chemicals
13
With full pages
4
Scaffold SMILES

O=C1NCCNC1=CC(=O)c1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C1NCCNC1=CC(=O)c1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 13 of 13 chemicals

Piperazinone, 3-(2-oxo-2-phenylethylidene)- chemical structure, C12H12N2O2, CAS 55135-12-1
Piperazinone, 3-(2-oxo-2-phenylethylidene)-
CAS 55135-12-1C12H12N2O2
Piperazinone, 3-(2-(4-methylphenyl)-2-oxoethylidene)- chemical structure, C13H14N2O2, CAS 63656-21-3
Piperazinone, 3-(2-(4-methylphenyl)-2-oxoethylidene)-
CAS 63656-21-3C13H14N2O2
(3E)-3-[2-(4-Chlorophenyl)-2-oxoethylidene]piperazin-2-one chemical structure, C12H11ClN2O2
(3E)-3-[2-(4-Chlorophenyl)-2-oxoethylidene]piperazin-2-one
C12H11ClN2O2
Piperazinone, 3-(2-(4-bromophenyl)-2-oxoethylidene)- chemical structure, C12H11BrN2O2, CAS 63656-19-9
Piperazinone, 3-(2-(4-bromophenyl)-2-oxoethylidene)-
CAS 63656-19-9C12H11BrN2O2
Piperazinone, 3-(2-(4-chlorophenyl)-2-oxoethylidene)- chemical structure, C12H11ClN2O2, CAS 63656-20-2
Piperazinone, 3-(2-(4-chlorophenyl)-2-oxoethylidene)-
CAS 63656-20-2C12H11ClN2O2
Piperazinone, 3-(2-(4-methoxyphenyl)-2-oxoethylidene)- chemical structure, C13H14N2O3, CAS 63656-22-4
Piperazinone, 3-(2-(4-methoxyphenyl)-2-oxoethylidene)-
CAS 63656-22-4C13H14N2O3
3-[2-(4-Chlorophenyl)-2-oxoethylidene]piperazin-2-one chemical structure, C12H11ClN2O2
3-[2-(4-Chlorophenyl)-2-oxoethylidene]piperazin-2-one
C12H11ClN2O2
3-(2-(2,4-Dimethylphenyl)-2-oxoethylidene)-1-methyl-2-piperazinone chemical structure, C15H18N2O2, CAS 178408-17-8
3-(2-(2,4-Dimethylphenyl)-2-oxoethylidene)-1-methyl-2-piperazinone
CAS 178408-17-8C15H18N2O2
(3E)-3-[2-(4-Ethoxyphenyl)-2-oxoethylidene]piperazin-2-one chemical structure, C14H16N2O3, CAS 177901-88-1
(3E)-3-[2-(4-Ethoxyphenyl)-2-oxoethylidene]piperazin-2-one
CAS 177901-88-1C14H16N2O3
Piperazinone, 1-methyl-3-(2-(4-methylphenyl)-2-oxoethylidene)- chemical structure, C14H16N2O2, CAS 178408-16-7
Piperazinone, 1-methyl-3-(2-(4-methylphenyl)-2-oxoethylidene)-
CAS 178408-16-7C14H16N2O2
Piperazinone, 3-(2-(4-methoxyphenyl)-2-oxoethylidene)-1-methyl- chemical structure, C14H16N2O3, CAS 178408-18-9
Piperazinone, 3-(2-(4-methoxyphenyl)-2-oxoethylidene)-1-methyl-
CAS 178408-18-9C14H16N2O3
Piperazinone, 3-(2-(4-fluorophenyl)-2-oxoethylidene)-1-methyl- chemical structure, C13H13FN2O2, CAS 178408-19-0
Piperazinone, 3-(2-(4-fluorophenyl)-2-oxoethylidene)-1-methyl-
CAS 178408-19-0C13H13FN2O2
Piperazinone, 3-(2-(4-bromophenyl)-2-oxoethylidene)-1-methyl- chemical structure, C13H13BrN2O2, CAS 178408-21-4
Piperazinone, 3-(2-(4-bromophenyl)-2-oxoethylidene)-1-methyl-
CAS 178408-21-4C13H13BrN2O2