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Murcko scaffold

Ring system with 3 rings and 15 atoms

5 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
15
Chemicals
5
With full pages
3
Scaffold SMILES

O=C1CCC2(c3ccccc3)SCCN12

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C1CCC2(c3ccccc3)SCCN12

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 5 of 5 chemicals

rac-(3R,7aR)-7a-(4-fluorophenyl)-5-oxo-hexahydropyrrolo[2,1-b][1,3]thiazole-3-carboxylic acid chemical structure, C13H12FNO3S, CAS 2832887-87-1
rac-(3R,7aR)-7a-(4-fluorophenyl)-5-oxo-hexahydropyrrolo[2,1-b][1,3]thiazole-3-carboxylic acid
CAS 2832887-87-1C13H12FNO3S
7A-(4-Methylphenyl)-5-oxo-hexahydropyrrolo[2,1-b][1,3]thiazole-3-carboxylic acid chemical structure, C14H15NO3S, CAS 1008704-37-7
7A-(4-Methylphenyl)-5-oxo-hexahydropyrrolo[2,1-b][1,3]thiazole-3-carboxylic acid
CAS 1008704-37-7C14H15NO3S
7a-(4-Fluorophenyl)-5-oxo-hexahydropyrrolo[2,1-b][1,3]thiazole-3-carboxylic acid chemical structure, C13H12FNO3S, CAS 1009269-94-6
7a-(4-Fluorophenyl)-5-oxo-hexahydropyrrolo[2,1-b][1,3]thiazole-3-carboxylic acid
CAS 1009269-94-6C13H12FNO3S
7a-(4-Bromophenyl)-5-oxo-hexahydropyrrolo[2,1-b][1,3]thiazole-3-carboxylic acid chemical structure, C13H12BrNO3S, CAS 1007999-08-7
7a-(4-Bromophenyl)-5-oxo-hexahydropyrrolo[2,1-b][1,3]thiazole-3-carboxylic acid
CAS 1007999-08-7C13H12BrNO3S
5-Oxo-7a-phenyl-hexahydropyrrolo(2,1-b)(1,3)thiazole-3-carboxylic acid chemical structure, C13H13NO3S, CAS 1008946-76-6
5-Oxo-7a-phenyl-hexahydropyrrolo(2,1-b)(1,3)thiazole-3-carboxylic acid
CAS 1008946-76-6C13H13NO3S