CompoundList
Sign in
Murcko scaffold

Ring system with 4 rings and 24 atoms

12 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
24
Chemicals
12
With full pages
3
Scaffold SMILES

O=C(Nc1ccc(Oc2ccnc3ccccc23)cc1)NC1CC1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(Nc1ccc(Oc2ccnc3ccccc23)cc1)NC1CC1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 12 of 12 chemicals

Lenvatinib chemical structure, C21H19ClN4O4, CAS 417716-92-8
Lenvatinib
CAS 417716-92-8C21H19ClN4O4
4-[3-Chloro-4-[[(cyclopropylamino)carbonyl]amino]phenoxy]-N,7-dimethoxy-6-quinolinecarboxamide chemical structure, C22H21ClN4O5, CAS 417717-44-3
4-[3-Chloro-4-[[(cyclopropylamino)carbonyl]amino]phenoxy]-N,7-dimethoxy-6-quinolinecarboxamide
CAS 417717-44-3C22H21ClN4O5
Lenvatinib mesylate chemical structure, C22H23ClN4O7S, CAS 857890-39-2
Lenvatinib mesylate
CAS 857890-39-2C22H23ClN4O7S
4-(3-Chloro-4-(cyclopropylaminocarbonyl)aminophenoxy)-7-methoxy-6-quinolinecarboxamide hydrochloride chemical structure, C21H20Cl2N4O4, CAS 857890-31-4
4-(3-Chloro-4-(cyclopropylaminocarbonyl)aminophenoxy)-7-methoxy-6-quinolinecarboxamide hydrochloride
CAS 857890-31-4C21H20Cl2N4O4
Lenvatinib impurity g chemical structure, C21H20N4O4, CAS 417714-14-8
Lenvatinib impurity g
CAS 417714-14-8C21H20N4O4
Methyl 4-(3-chloro-4-(3-cyclopropylureido)phenoxy)-7-methoxyquinoline-6-carboxylate chemical structure, C22H20ClN3O5, CAS 417717-20-5
Methyl 4-(3-chloro-4-(3-cyclopropylureido)phenoxy)-7-methoxyquinoline-6-carboxylate
CAS 417717-20-5C22H20ClN3O5
Lenvatinib impurity F chemical structure, C21H18ClN3O5, CAS 417717-21-6
Lenvatinib impurity F
CAS 417717-21-6C21H18ClN3O5
Lenvatinib N-oxide chemical structure, C21H19ClN4O5, CAS 1788901-86-9
Lenvatinib N-oxide
CAS 1788901-86-9C21H19ClN4O5
1-(2-Chloro-4-((6-cyano-7-methoxyquinolin-4-yl)oxy)phenyl)-3-cyclopropylurea chemical structure, C21H17ClN4O3, CAS 1882873-21-3
1-(2-Chloro-4-((6-cyano-7-methoxyquinolin-4-yl)oxy)phenyl)-3-cyclopropylurea
CAS 1882873-21-3C21H17ClN4O3
4-(3-Chloro-4-(((cyclopropylamino)carbonyl)amino)phenoxy)-7-hydroxy-6-quinolinecarboxamide chemical structure, C20H17ClN4O4, CAS 417717-04-5
4-(3-Chloro-4-(((cyclopropylamino)carbonyl)amino)phenoxy)-7-hydroxy-6-quinolinecarboxamide
CAS 417717-04-5C20H17ClN4O4
Lenvatinib-d4 chemical structure, C21H19ClN4O4, CAS 2264050-65-7
Lenvatinib-d4
CAS 2264050-65-7C21H19ClN4O4
Lenvatinib besylate chemical structure, C27H25ClN4O7S, CAS 2414382-25-3
Lenvatinib besylate
CAS 2414382-25-3C27H25ClN4O7S